Search Results - "S. Zaghlool, Sameh"
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The protective effect of thymoquinone or/and thymol against monosodium glutamate-induced attention-deficit/hyperactivity disorder (ADHD)-like behavior in rats: Modulation of Nrf2/HO-1, TLR4/NF-κB/NLRP3/caspase-1 and Wnt/β-Catenin signaling pathways in rat model
Published in Biomedicine & pharmacotherapy (01-11-2022)“…Both thymoquinone (TQ) and thymol (T) have been proved to possess a positive impact on human health. In this research, we aimed to investigate the effect of…”
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The protective effects of sesamol and/or the probiotic, Lactobacillus rhamnosus, against aluminum chloride-induced neurotoxicity and hepatotoxicity in rats: Modulation of Wnt/β-catenin/GSK-3β, JAK-2/STAT-3, PPAR-γ, inflammatory, and apoptotic pathways
Published in Frontiers in pharmacology (02-08-2023)“…Introduction: Aluminium (Al) is accumulated in the brain causing neurotoxicity and neurodegenerative disease like Alzheimer's disease (AD), multiple sclerosis,…”
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Neuroprotective Effects of Phytochemicals against Aluminum Chloride-Induced Alzheimer’s Disease through ApoE4/LRP1, Wnt3/β-Catenin/GSK3β, and TLR4/NLRP3 Pathways with Physical and Mental Activities in a Rat Model
Published in Pharmaceuticals (Basel, Switzerland) (01-08-2022)“…Background: Alzheimer’s disease (AD) is a neurodegenerative disorder that is associated with abnormal cognition. AD is aided in its initiation and progression…”
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Nifuroxazide-loaded cubosomes exhibit an advancement in pulmonary delivery and attenuate bleomycin-induced lung fibrosis by regulating the STAT3 and NF-κB signaling: A new challenge for unmet therapeutic needs
Published in Biomedicine & pharmacotherapy (01-04-2022)“…Pulmonary fibrosis (PF) is a chronic progressive disease that portends a very poor prognosis. It has been suggested that STAT3 is a potential target in PF…”
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Corrigendum to “The protective effect of thymoquinone or/and thymol against monosodium glutamate-induced attention-deficit/hyperactivity disorder (ADHD)-like behavior in rats: Modulation of Nrf2/HO-1, TLR4/NF-κB/NLRP3/caspase-1 and Wnt/β-Catenin signaling pathways in rat model” [Biomed. Pharmacother. 155 (2022) 113799]
Published in Biomedicine & pharmacotherapy (01-06-2023)Get full text
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Neuroprotective Effects of Some Nutraceuticals against Manganese-Induced Parkinson's Disease in Rats: Possible Modulatory Effects on TLR4/NLRP3/NF-κB, GSK-3β, Nrf2/HO-1, and Apoptotic Pathways
Published in Pharmaceuticals (Basel, Switzerland) (01-12-2022)“…Parkinson's disease (PD) is a progressive neurodegenerative disorder affecting the substantia nigra where functions controlling body movement take place…”
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Emerging Anthelmintic Resistance in Poultry: Can Ethnopharmacological Approaches Offer a Solution?
Published in Frontiers in pharmacology (14-02-2022)“…Limited pharmacological studies have been conducted on plant species used against poultry helminths. The objective of this study was to provide a basis for…”
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Gastro-Protective and Anti-Oxidant Potential of Althaea officinalis and Solanum nigrum on Pyloric Ligation/Indomethacin-Induced Ulceration in Rats
Published in Antioxidants (25-10-2019)“…Recently, an alternative disease treatment approach is the research of medicaments from traditional medicine. Plants with anti-oxidant capabilities are used as…”
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Advancements in SARS-CoV-2 detection: Navigating the molecular landscape and diagnostic technologies
Published in Heliyon (15-05-2024)“…According to information from the World Health Organization, the world has experienced about 430 million cases of COVID-19, a world-wide health crisis caused…”
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Melatonin and zinc supplements with physical and mental activities subside neurodegeneration and hepatorenal injury induced by aluminum chloride in rats: Inclusion of GSK-3β-Wnt/β-catenin signaling pathway
Published in Neurotoxicology (Park Forest South) (01-07-2022)“…Alzheimer's disease (AD) is an irreversible, progressive cognitive dysfunction. Inflammaging is the greatest common factor between AD and hepatorenal…”
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Restoring glomerular filtration rate by sulforaphane modulates ERK1/2/JNK/p38MAPK, IRF3/iNOS, Nrf2/HO-1 signaling pathways against folic acid-induced acute renal injury in rats
Published in International immunopharmacology (01-10-2023)“…Folic acid (FA)-induced acute renal injury (AKI) is a commonly and highly reproducible model used to study AKI. The current study aims to evaluate the possible…”
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Optimization and clinical evaluation of hyaluronic acid proniosome loaded in-situ gel for the management of recurrent aphthous stomatitis
Published in Journal of drug delivery science and technology (01-10-2024)“…Recurrent aphthous stomatitis (RAS) is a frequent unpleasant oral condition that causes ulcers. Hyaluronic acid (HY) is an inherent polymer owing antioxidant,…”
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Protective effects of ginger and marshmallow extracts on indomethacin-induced peptic ulcer in rats
Published in Journal of natural science, biology and medicine (01-07-2015)“…Background: Gastric ulcer is one of the most serious diseases. Most classic treatment lines produce adverse drug reactions. Therefore, this study aimed to…”
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