Search Results - "S. Mook"
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Online adaptive MR-guided radiotherapy for rectal cancer; feasibility of the workflow on a 1.5T MR-linac: clinical implementation and initial experience
Published in Radiotherapy and oncology (01-01-2021)“…•MR-guided radiotherapy for rectal cancer on a 1.5T MR-linac is feasible.•An online adaptive workflow takes about 48 min each fraction.•Treatment of rectal…”
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Endobronchial Ultrasonography to Assess and Evaluate Tracheobronchial Tree Invasion in cT4b Esophageal Cancer Patients Treated with Definitive Chemoradiotherapy: Assessment of Resectability
Published in Annals of surgical oncology (06-07-2024)“…In cT4b esophageal cancer, accurate assessment of tracheobronchial tree invasion after definitive chemoradiotherapy (dCRT) aids in the selection of patients…”
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The 70-gene prognosis signature predicts early metastasis in breast cancer patients between 55 and 70 years of age
Published in Annals of oncology (01-04-2010)“…The majority of breast cancer patients are postmenopausal women who are increasingly being offered adjuvant chemotherapy. Since the beneficial effect of…”
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Technical feasibility of magnetic resonance fingerprinting on a 1.5T MRI-linac
Published in Physics in medicine & biology (21-11-2020)“…Hybrid MRI-linac (MRL) systems enable daily multiparametric quantitative MRI to assess tumor response to radiotherapy. Magnetic resonance fingerprinting (MRF)…”
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Salvage Robot-Assisted Minimally Invasive Esophagectomy (RAMIE) for T4b Esophageal Cancer After Definitive Chemoradiotherapy
Published in Annals of surgical oncology (01-05-2021)“…Background Patients with esophageal cancer that invades adjacent structures (cT4b) are precluded from surgery and usually treated with definitive…”
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Safety and Feasibility of Robot-Assisted Minimally Invasive Esophagectomy (RAMIE) with Three-Field Lymphadenectomy and Neoadjuvant Chemoradiotherapy in Patients with Resectable Esophageal Cancer and Cervical Lymph Node Metastasis
Published in Annals of surgical oncology (01-05-2023)“…Background In the West, patients with cervical lymph node metastasis of resectable esophageal cancer at diagnosis are generally precluded from curative…”
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ASO Visual Abstract: Safety and Feasibility of Robot-Assisted Minimally Invasive Esophagectomy (RAMIE) with Three-Field Lymphadenectomy and Neoadjuvant Chemoradiotherapy in Patients with Resectable Esophageal Cancer and Cervical Lymph Node Metastasis
Published in Annals of surgical oncology (01-05-2023)Get full text
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Diagnostic performance of MRI for assessment of response to neoadjuvant chemoradiotherapy in oesophageal cancer
Published in British journal of surgery (01-04-2019)“…Background Patients with a pathological complete response (pCR) after neoadjuvant chemoradiotherapy (nCRT) for oesophageal cancer may benefit from non‐surgical…”
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CTV-to-PTV margin assessment for esophageal cancer radiotherapy based on an accumulated dose analysis
Published in Radiotherapy and oncology (01-08-2021)“…•The smallest clinical target volume (CTV) to planned target volume (PTV) margins that yielded full dosimetric coverage for esophageal cancer radiotherapy were…”
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3-Dimensional target coverage assessment for MRI guided esophageal cancer radiotherapy
Published in Radiotherapy and oncology (01-06-2020)“…•Online MR-guided soft-tissue registration protocols exhibited modest improvements of the geometric target coverage probability as compared to online…”
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Clinical implementation and feasibility of long-course fractionated MR-guided chemoradiotherapy for patients with esophageal cancer: An R-IDEAL stage 1b/2a evaluation of technical innovation
Published in Clinical and translational radiation oncology (01-05-2022)“…•Online MR-guided long-course fractionated chemoradiotherapy for patients with esophageal cancer was feasible in 7 out of 9 patients.•Median treatment time was…”
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ypT0N+ status in oesophageal cancer patients: Location of residual metastatic lymph nodes with regard to the neoadjuvant radiation field
Published in European journal of surgical oncology (01-03-2019)“…A subset of oesophageal cancer patients has residual nodal disease despite complete pathologic response of the primary tumour after neoadjuvant chemoradiation…”
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Additional prognostic value of the 70-gene signature (MammaPrint® ) among breast cancer patients with 4–9 positive lymph nodes
Published in Breast (Edinburgh) (01-10-2013)“…Abstract Background The 70 gene-signature (MammaPrint® ) is a prognostic profile of distant recurrence and survival of primary breast cancer (BC). BC patients…”
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PO-0703: Perioperative chemotherapy versus neoadjuvant chemoradiotherapy for esophageal adenocarcinoma
Published in Radiotherapy and oncology (01-04-2016)Get full text
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Effect of a prediction tool and communication skills training on communication of treatment outcomes: a multicenter stepped wedge clinical trial (the SOURCE trial)
Published in EClinicalMedicine (01-10-2023)“…For cancer patients to effectively engage in decision making, they require comprehensive and understandable information regarding treatment options and their…”
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Daily clinical practice of fresh tumour tissue freezing and gene expression profiling; logistics pilot study preceding the MINDACT trial
Published in European Journal of Cancer (01-05-2009)“…Abstract Purpose The 70-gene prognosis-signature is a prognostic tool for early breast cancer analysis. In addition to scientific evidence, implementation of…”
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Additional value of the 70-gene signature and levels of ER and PR for the prediction of outcome in tamoxifen-treated ER-positive breast cancer
Published in Breast (Edinburgh) (01-12-2012)“…Abstract Background Breast cancer patients with node positive disease can have an excellent outcome with tamoxifen only. It is unclear whether analysing both…”
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In vivo regulation of plasma free fatty acids in insulin resistance
Published in Metabolism, clinical and experimental (01-09-2004)“…Elevated plasma free fatty acid (FFA) concentrations as seen in obesity, insulin resistance, and type 2 diabetes are partly caused by impaired inhibition of…”
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SP-0393: Clinical opportunities with MR guided external beam RT
Published in Radiotherapy and oncology (01-05-2017)Get full text
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