Search Results - "S. Leucht"

Validation of the rating scales for negative symptoms: new strategies by Leucht, S, Wehr, S

“…Negative symptoms of schizophrenia are linked with poor functioning and quality of life. Therefore, appropriate measurement tools to assess negative symptoms…”
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Physical illness and schizophrenia: a review of the literature by Leucht, S., Burkard, T., Henderson, J., Maj, M., Sartorius, N.

“…Objective:  The lifespan of people with schizophrenia is shortened compared to the general population. We reviewed the literature on comorbid physical diseases…”
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How effective are second-generation antipsychotic drugs? A meta-analysis of placebo-controlled trials by Leucht, S, Arbter, D, Engel, R R, Kissling, W, Davis, J M

“…We conducted a systematic review and meta-analysis of randomized controlled trials that compared second-generation antipsychotic (SGA) drugs with placebo in…”
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Long-Acting Injectable vs Oral Antipsychotics for Relapse Prevention in Schizophrenia: A Meta-Analysis of Randomized Trials by KISHIMOTO, Taishiro, ROBENZADEH, Alfred, LEUCHT, Claudia, LEUCHT, Stefan, WATANABE, Koichiro, MIMURA, Masaru, BORENSTEIN, Michael, KANE, John M, CORRELL, Christoph U

“…While long-acting injectable antipsychotics (LAIs) are hoped to reduce high relapse rates in schizophrenia, recent randomized controlled trials (RCTs)…”
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Clozapine as a first‐ or second‐line treatment in schizophrenia: a systematic review and meta‐analysis by Okhuijsen‐Pfeifer, C., Huijsman, E. A. H., Hasan, A., Sommer, I. E. C., Leucht, S., Kahn, R. S., Luykx, J. J.

“…Objective No consensus exists on whether clozapine should be prescribed in early stages of psychosis. This systematic review and meta‐analysis therefore focus…”
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Relapse prevention in schizophrenia: a systematic review and meta-analysis of second-generation antipsychotics versus first-generation antipsychotics by Kishimoto, T, Agarwal, V, Kishi, T, Leucht, S, Kane, J M, Correll, C U

“…Few controlled trials compared second-generation antipsychotics (SGAs) with first-generation antipsychotics (FGAs) regarding relapse prevention in…”
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Dose Equivalents for Second-Generation Antipsychotics: The Minimum Effective Dose Method by LEUCHT, Stefan, SAMARA, Myrto, HERES, Stephan, PATEL, Maxine X, WOODS, Scott W, DAVIS, John M

“…Clinicians need to know the right antipsychotic dose for optimized treatment, and the concept of dose equivalence is important for many clinical and scientific…”
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Second-generation antipsychotics for schizophrenia: can we resolve the conflict? by Leucht, S, Kissling, W, Davis, J M

“…The initial enthusiasm about the second-generation or atypical antipsychotic drugs soon changed into criticism and debate, culminating in the controversial…”
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Second-generation antipsychotic effect on cognition in patients with schizophrenia-a meta-analysis of randomized clinical trials by Nielsen, R. E., Levander, S., Kjaersdam Telléus, G., Jensen, S. O. W., Østergaard Christensen, T., Leucht, S.

“…Objective To investigate the effect of second‐generation antipsychotics on cognitive function in patients diagnosed with schizophrenia or schizoaffective…”
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Efficacy, acceptability, and tolerability of all available treatments for insomnia in the elderly: a systematic review and network meta‐analysis by Samara, M. T., Huhn, M., Chiocchia, V., Schneider‐Thoma, J., Wiegand, M., Salanti, G., Leucht, S.

“…Objectives Symptoms of insomnia are highly prevalent in the elderly. A significant number of pharmacological and non‐pharmacological interventions exist, but,…”
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S.05.03 Atypical antipsychotics in bipolar disorder and schizophrenia: similarities and discrepancies by Leucht, S

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Initial severity of major depression and efficacy of new generation antidepressants: individual participant data meta‐analysis by Furukawa, T. A., Maruo, K., Noma, H., Tanaka, S., Imai, H., Shinohara, K., Ikeda, K., Yamawaki, S., Levine, S. Z., Goldberg, Y., Leucht, S., Cipriani, A.

“…Objective The role of baseline severity as effect modifier in various psychiatric disorders is a topic of controversy and of clinical import. This study aims…”
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Equipercentile linking of the BPRS and the PANSS by Leucht, S, Rothe, P, Davis, J.M, Engel, R.R

“…Abstract The Positive and Negative Syndrome Scale (PANSS) and the Brief Psychiatric Rating Scale (BPRS) are the most frequently used scales to rate the…”
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No benefit from flexible titration above minimum licensed dose in prescribing antidepressants for major depression: systematic review by Furukawa, T. A., Salanti, G., Cowen, P. J., Leucht, S., Cipriani, A.

“…Background In fixed‐dose antidepressant trials, the lower range of the licensed dose achieves the optimal balance between efficacy and tolerability. Whether…”
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A white paper on a neurodevelopmental framework for drug discovery in autism and other neurodevelopmental disorders by Díaz-Caneja, CM, State, MW, Hagerman, RJ, Jacquemont, S, Marín, O, Bagni, C, Umbricht, D, Simonoff, E, de Andrés-Trelles, F, Kaale, A, Pandina, G, Gómez-Mancilla, B, Wang, PP, Cusak, J, Siafis, S, Leucht, S, Parellada, M, Loth, E, Charman, T, Buitelaar, JK, Murphy, D, Arango, C

“…In the last decade there has been a revolution in terms of genetic findings in neurodevelopmental disorders (NDDs), with many discoveries critical for…”
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C.13.03 Translating the evidence on the clinical benefits of antipsychotics for routine practice by Leucht, S

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Definitions of response and remission in schizophrenia: recommendations for their use and their presentation by Leucht, S., Davis, J. M., Engel, R. R., Kissling, W., Kane, J. M.

“…Objective:  To review and make recommendations for the definition and presentation of the terms ‘response’ and ‘remission’ in schizophrenia. Method:  Selective…”
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Antipsychotic Combinations vs Monotherapy in Schizophrenia: A Meta-analysis of Randomized Controlled Trials by Correll, Christoph U., Rummel-Kluge, Christine, Corves, Caroline, Kane, John M., Leucht, Stefan

“…Context: Despite lacking evidence for its safety and efficacy, antipsychotic cotreatment is common in schizophrenia. Objective: To evaluate therapeutic and…”
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The concepts of remission and recovery in schizophrenia by Leucht, S, Lasser, R

“…To examine the past and current research into the concepts of remission and recovery in schizophrenia. An electronic literature search of studies published…”
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Magnetic resonance imaging and the prediction of outcome in first-episode schizophrenia: a review of current evidence and directions for future research by Dazzan, Paola, Arango, Celso, Fleischacker, Wolfgang, Galderisi, Silvana, Glenthøj, Birte, Leucht, Stephan, Meyer-Lindenberg, Andreas, Kahn, Rene, Rujescu, Dan, Sommer, Iris, Winter, Inge, McGuire, Philip

“…Magnetic Resonance Imaging (MRI) measures are promising outcome markers for schizophrenia, since regional frontal and temporal grey matter volumes reductions,…”
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