Search Results - "S. Kitara"

Blockade of oncogenic notch1 with the new serca inhibitor cad204520 in t-cell acute lymphoblastic leukemia by M. Marchesini, A. Gherli, A. Montanaro, C. Sorrentino, L. Pagliaro, C. Rompietti, S. Kitara, F. Rizzi, D. Stilli, R. La Starza, C. Mecucci, K. Stegmaier, A.M. Lund Winter, P. Sportoletti, M. Bublitz, W. Dalby-Brown, G. Roti

“…The discovery of the P-type ATPase Sarco/Endoplasmic Reticulum Ca2+-ATPase (SERCA) as a bidirectional modulator of oncogenic NOTCH1 suggests an innovative…”
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PF158 TARGETING ONCOGENIC NOTCH1 IN T‐CELL ACUTE LYMPHOBLASTIC LEUKEMIA WITH A NEW SELECTIVE SERCA INHIBITOR CAD204520 by Marchesini, M., Gherli, A., Winter, A.‐M. Lund, Patrizi, L., Kitara, S., Montanaro, A., Rompietti, C., Sorrentino, C., Stilli, D., Rizzi, F., Loiacono, C., Pagliaro, L., La Starza, R., Mecucci, C., Aversa, F., Sportoletti, P., Dalby‐Brown, W., Roti, G.

“…Background: Several studies support the development of NOTCH1 inhibitors for targeted cancer therapy. This idea is most compelling for T‐cell acute…”
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