Search Results - "S Scheucher, P."

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    CCAAT/enhancer-binding protein alpha (CEBPA) gene haploinsufficiency does not alter hematopoiesis or induce leukemia in Lck-CALM/AF10 transgenic mice by Lange, A P, Almeida, L Y, Araújo Silva, C L, Scheucher, P S, Chahud, F, Krause, A, Bohlander, S K, Rego, E M

    “…Although rare, CALM/AF10 is a chromosomal rearrangement found in immature T-cell acute lymphoblastic leukemia (T-ALL), acute myeloid leukemia, and mixed…”
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    Telomere length analysis in monoclonal B-cell lymphocytosis and chronic lymphocytic leukemia Binet A by Furtado, F M, Scheucher, P S, Santana, B A, Scatena, N F, Calado, R T, Rego, E M, Matos, D M, Falcão, R P

    “…Monoclonal B-cell lymphocytosis (MBL) is an asymptomatic clinical entity characterized by the proliferation of monoclonal B cells not meeting the diagnosis…”
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    IMMUNOPHENOTYPIC SIGNATURE OF LEUKEMIA ARREST STAGE IS ASSOCIATED WITH NPM1/FLT3 MUTATIONAL PROFILE AND PROGNOSIS IN ACUTE MYELOID LEUKEMIA by AG Carvalho, LO Marani, CAB Garcia, M Medeiros, LS Binelli, AFO Costa, EVB Ferreira, JLS Schiavinato, PS Scheucher, LL Figueiredo-Pontes

    Published in Hematology, Transfusion and Cell Therapy (01-10-2024)
    “…Acute Myeloid Leukemia (AML) is a severe hematopoietic disorder marked by uncontrolled proliferation of immature myeloid progenitors due to differentiation…”
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    CYTOTOXIC IMMUNE CELLS MATURATION IN MYELOFIBROSIS: IMPLICATIONS FOR DISEASE PROGRESSION by M Medeiros, CAB Garcia, LS Binelli, AG Carvalho, LO Marani, PS Scheucher, JLDS Schiavinato, LC Palma, PMM Garibaldi, LL Figueiredo-Pontes

    Published in Hematology, Transfusion and Cell Therapy (01-10-2024)
    “…Myelofibrosis (MF), driven by JAK/STAT signaling mutations in hematopoietic stem cells, has the worst survival rates among myeloproliferative neoplasms (MPNs),…”
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    IMMUNOLOGICAL PROFILES OF CYTOTOXIC CELLS IS ASSOCIATED WITH TREATMENT-FREE REMISSION IN CHRONIC MYELOID LEUKEMIA by LS Binelli, LC Palma, CAB Garcia, LO Marani, M Medeiros, AG Carvalho, PS Scheucher, JLS Schiavinato, PMM Garibaldi, RS Welner, FA Castro, KBB Pagnano, LL Figueiredo-Pontes

    Published in Hematology, Transfusion and Cell Therapy (01-10-2024)
    “…Patients with Chronic Myeloid Leukemia (CML) who achieve sustained deep molecular response (DMR) to Tyrosine Kinase Inhibitors (TKIs) are eligible for…”
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    ABSENT CD33 IN AML PATIENT MIMICS MRD POSITIVE: A SINGLE CASE REPORT by LO Marani, AFO Costa, FB Silva, MIA Madeira, PS Scheucher, JL Schiavinato, ASG Lima, KBB Pagnano, BK Duarte, S Freeman, F Traina, EM Rego, LL Figueiredo-Pontes

    Published in Hematology, Transfusion and Cell Therapy (01-10-2021)
    “…Background: Diagnosis and treatment of acute myeloid leukemia (AML) remains difficult to this day, cure rates remain low and measurable residual disease (MRD)…”
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    PERFIS IMUNOFENOTÍPICOS NA LEUCEMIA LINFOIDE AGUDA DE LINHAGEM B: UMA ANÁLISE RETROSPECTIVA UTILIZANDO CITOMETRIA DE FLUXO MULTIPARAMÉTRICA by LO Marani, MG Rosa, RL Pacca, JTB Faria, PS Scheucher, JL Schiavinato, TE Gonçalves, LL Figueiredo-Pontes

    Published in Hematology, Transfusion and Cell Therapy (01-10-2024)
    “…A Leucemia Linfoide Aguda (LLA) é uma neoplasia hematológica caracterizada pela proliferação descontrolada de células progenitoras linfoides B ou T,…”
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    VALIDAÇÃO METODOLÓGICA NA ANÁLISE DE SUBPOPULAÇÕES LINFOCITÁRIAS ENTRE CITÔMETROS DE FLUXO by LO Marani, MG Rosa, PS Scheucher, JL Schiavinato, TE Gonçalves, LL Figueiredo-Pontes

    Published in Hematology, Transfusion and Cell Therapy (01-10-2024)
    “…Introdução: A quantificação de linfócitos T, B e Natural Killer (NK) por citometria de fluxo é o confiável para avaliar a imunocompetência do organismo,…”
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    A CLOROQUINA REVERTE RESISTÊNCIA E POTENCIALIZA O EFEITO ANTILEUCÊMICO DOS INIBIDORES DE FLT3 EM LEUCEMIA MIELOIDE AGUDA by MA Melo, DA Pereira-Martins, BGS Macedo, PS Scheucher, JA Machado-Neto, F Traina

    Published in Hematology, Transfusion and Cell Therapy (01-10-2024)
    “…Objetivos: A autofagia foi recentemente postulada como um potencial mecanismo que contribui para o desenvolvimento de resistência aos inibidores de FLT3…”
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    O NOCAUTE DE IRS2 IMPACTA A CONSTITUIÇÃO EM LONGO PRAZO DAS SUBPOPULAÇÕES DE CÉLULAS-TRONCO HEMATOPOETICAS by BA Fenerich, AB Alves-Silva, NP Fonseca, JC Fernandes, JL Coelho-Silva, CLA Silva, PS Scheucher, JA Machado-Neto, F Traina

    Published in Hematology, Transfusion and Cell Therapy (01-10-2021)
    “…Objetivos: O substrato do receptor de insulina 2 (IRS2) interage com receptores envolvidos no processo hematopoético e sua expressão é reduzida em pacientes…”
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    MATURAÇÃO FUNCIONAL E ATIVAÇÃO DE CÉLULAS NATURAL KILLER DISTINGUEM MIELOFIBROSE PRÉ-FIBRÓTICA E FIBRÓTICA by M Medeiros, CAB Garcia, LS Binélli, IA Lopes, JTB Faria, PS Scheucher, JLDS Schiavinato, LL Figueired-Pontes

    Published in Hematology, Transfusion and Cell Therapy (01-10-2023)
    “…A Mielofibrose Primária (MFP) é uma neoplasia mieloproliferativa iniciada por mutações na célula-tronco hematopoética (e. g. JAK2V617F) e pode ser classificada…”
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    RECLASSIFICAÇÃO DA LEUCEMIA MIELOIDE AGUDA DE ACORDO COM A CÉLULA DE ORIGEM FENOTIPICAMENTE DEFINIDA by RCB Macedo, CAB Garcia, MIA Madeira, AFO Costa, LO Marani, PS Scheucher, J Schiavinato, K Pagnano, BK Lino, F Kerbaury, E Nunes, ABF Glória, EM Rego, F Traina, LL Figueired-Pontes

    Published in Hematology, Transfusion and Cell Therapy (01-10-2023)
    “…A Leucemia Mieloide Aguda (LMA) se origina de anormalidades genéticas ao nível das células-tronco hematopoéticas (CTH), que adquirem propriedades de…”
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    AVALIAÇÃO DE VIABILIDADE DE DETECÇÃO DE DRM EM LLA-B POR CITOMETRIA DE FLUXO MULTIPARAMÉTRICA INDEPENDENTE DE CD19 by R Pacca, LO Marani, LFB Catto, TE Gonçalves, JL Schiavinato, PS Scheucher, CAB Garcia, MIA Madeira, DV Clé, LL Figueired-Pontes

    Published in Hematology, Transfusion and Cell Therapy (01-10-2023)
    “…A Leucemia Linfoblástica Aguda (LLA) é uma neoplasia de células linfoides imaturas T ou B, sendo a segunda leucemia aguda mais comum no adulto. Acomete cerca…”
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