Search Results - "S Scheucher, P."
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(+)α-Tocopheryl succinate inhibits the mitochondrial respiratory chain complex I and is as effective as arsenic trioxide or ATRA against acute promyelocytic leukemia in vivo
Published in Leukemia (01-03-2012)“…The vitamin E derivative (+)α-tocopheryl succinate (α-TOS) exerts pro-apoptotic effects in a wide range of tumors and is well tolerated by normal tissues…”
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CCAAT/enhancer-binding protein alpha (CEBPA) gene haploinsufficiency does not alter hematopoiesis or induce leukemia in Lck-CALM/AF10 transgenic mice
Published in Brazilian journal of medical and biological research (01-01-2019)“…Although rare, CALM/AF10 is a chromosomal rearrangement found in immature T-cell acute lymphoblastic leukemia (T-ALL), acute myeloid leukemia, and mixed…”
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Telomere length analysis in monoclonal B-cell lymphocytosis and chronic lymphocytic leukemia Binet A
Published in Brazilian journal of medical and biological research (01-01-2017)“…Monoclonal B-cell lymphocytosis (MBL) is an asymptomatic clinical entity characterized by the proliferation of monoclonal B cells not meeting the diagnosis…”
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P396: DYSREGULATED DNAM‐1 AND KIR2DL1 EXPRESSION IN NATURAL KILLER CELLS CORRELATES WITH POOR OUTCOME IN ACUTE MYELOID LEUKEMIA
Published in HemaSphere (23-06-2022)Get full text
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PB1814: RARE PHENOTYPE WITH CD33 ABSENT IN ACUTE MYELOID LEUKEMIA MIMICKING MRD POSITIVITY: A CASE REPORT
Published in HemaSphere (23-06-2022)Get full text
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IMMUNOPHENOTYPIC SIGNATURE OF LEUKEMIA ARREST STAGE IS ASSOCIATED WITH NPM1/FLT3 MUTATIONAL PROFILE AND PROGNOSIS IN ACUTE MYELOID LEUKEMIA
Published in Hematology, Transfusion and Cell Therapy (01-10-2024)“…Acute Myeloid Leukemia (AML) is a severe hematopoietic disorder marked by uncontrolled proliferation of immature myeloid progenitors due to differentiation…”
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CYTOTOXIC IMMUNE CELLS MATURATION IN MYELOFIBROSIS: IMPLICATIONS FOR DISEASE PROGRESSION
Published in Hematology, Transfusion and Cell Therapy (01-10-2024)“…Myelofibrosis (MF), driven by JAK/STAT signaling mutations in hematopoietic stem cells, has the worst survival rates among myeloproliferative neoplasms (MPNs),…”
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IMMUNOLOGICAL PROFILES OF CYTOTOXIC CELLS IS ASSOCIATED WITH TREATMENT-FREE REMISSION IN CHRONIC MYELOID LEUKEMIA
Published in Hematology, Transfusion and Cell Therapy (01-10-2024)“…Patients with Chronic Myeloid Leukemia (CML) who achieve sustained deep molecular response (DMR) to Tyrosine Kinase Inhibitors (TKIs) are eligible for…”
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ABSENT CD33 IN AML PATIENT MIMICS MRD POSITIVE: A SINGLE CASE REPORT
Published in Hematology, Transfusion and Cell Therapy (01-10-2021)“…Background: Diagnosis and treatment of acute myeloid leukemia (AML) remains difficult to this day, cure rates remain low and measurable residual disease (MRD)…”
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Interaction of 10-(octyloxy) decyl-2-(trimethylammonium) ethyl phosphate with mimetic membranes and cytotoxic effect on leukemic cells
Published in Biochimica et biophysica acta (01-09-2010)“…10-(Octyloxy) decyl-2-(trimethylammonium) ethyl phosphate (ODPC) is an alkylphospholipid that can interact with cell membranes because of its amphiphilic…”
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UNRAVELLING THE HIGH INCIDENCE OF ACUTE MYELOID LEUKEMIA WITH MONOCYTIC BLAST DIFFERENTIATION IN A BRAZILIAN MULTICENTER STUDY
Published in Hematology, Transfusion and Cell Therapy (01-10-2021)“…Background: Acute myeloid leukemia with monocytic blast differentiation (AML-MC) is a rare malignancy (5-10% incidence) with a challenging diagnosis,…”
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PERFIS IMUNOFENOTÍPICOS NA LEUCEMIA LINFOIDE AGUDA DE LINHAGEM B: UMA ANÁLISE RETROSPECTIVA UTILIZANDO CITOMETRIA DE FLUXO MULTIPARAMÉTRICA
Published in Hematology, Transfusion and Cell Therapy (01-10-2024)“…A Leucemia Linfoide Aguda (LLA) é uma neoplasia hematológica caracterizada pela proliferação descontrolada de células progenitoras linfoides B ou T,…”
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VALIDAÇÃO METODOLÓGICA NA ANÁLISE DE SUBPOPULAÇÕES LINFOCITÁRIAS ENTRE CITÔMETROS DE FLUXO
Published in Hematology, Transfusion and Cell Therapy (01-10-2024)“…Introdução: A quantificação de linfócitos T, B e Natural Killer (NK) por citometria de fluxo é o confiável para avaliar a imunocompetência do organismo,…”
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A CLOROQUINA REVERTE RESISTÊNCIA E POTENCIALIZA O EFEITO ANTILEUCÊMICO DOS INIBIDORES DE FLT3 EM LEUCEMIA MIELOIDE AGUDA
Published in Hematology, Transfusion and Cell Therapy (01-10-2024)“…Objetivos: A autofagia foi recentemente postulada como um potencial mecanismo que contribui para o desenvolvimento de resistência aos inibidores de FLT3…”
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DOENÇA RESIDUAL MENSURÁVEL POR CITOMETRIA DE FLUXO MULTIPARAMÉTRICA É VIÁVEL E DETERMINA RISCO PROGNÓSTICO DINÂMICO EM PACIENTES DE UMA COORTE BRASILEIRA DE LEUCEMIA MIELOIDE AGUDA
Published in Hematology, Transfusion and Cell Therapy (01-10-2023)“…O monitoramento da Leucemia Mieloide Aguda (LMA) é uma estratégia de avaliação prognóstica para identificar Doença Residual Mensurável (DRM). Indica-se o…”
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FREQUÊNCIA E ATIVAÇÃO DE CÉLULAS CITOTÓXICAS ANTITUMORAIS SÃO BIOMARCADORES DE RESPOSTA E REMISSÃO LIVRE DE TRATAMENTO NA LEUCEMIA MIELOIDE CRÔNICA
Published in Hematology, Transfusion and Cell Therapy (01-10-2023)“…Na Leucemia Mieloide Crônica (LMC), pacientes que alcançam resposta molecular profunda sustentada (RMP) com inibidor de tirosinoquinase (ITQ) podem ter o…”
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O NOCAUTE DE IRS2 IMPACTA A CONSTITUIÇÃO EM LONGO PRAZO DAS SUBPOPULAÇÕES DE CÉLULAS-TRONCO HEMATOPOETICAS
Published in Hematology, Transfusion and Cell Therapy (01-10-2021)“…Objetivos: O substrato do receptor de insulina 2 (IRS2) interage com receptores envolvidos no processo hematopoético e sua expressão é reduzida em pacientes…”
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MATURAÇÃO FUNCIONAL E ATIVAÇÃO DE CÉLULAS NATURAL KILLER DISTINGUEM MIELOFIBROSE PRÉ-FIBRÓTICA E FIBRÓTICA
Published in Hematology, Transfusion and Cell Therapy (01-10-2023)“…A Mielofibrose Primária (MFP) é uma neoplasia mieloproliferativa iniciada por mutações na célula-tronco hematopoética (e. g. JAK2V617F) e pode ser classificada…”
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RECLASSIFICAÇÃO DA LEUCEMIA MIELOIDE AGUDA DE ACORDO COM A CÉLULA DE ORIGEM FENOTIPICAMENTE DEFINIDA
Published in Hematology, Transfusion and Cell Therapy (01-10-2023)“…A Leucemia Mieloide Aguda (LMA) se origina de anormalidades genéticas ao nível das células-tronco hematopoéticas (CTH), que adquirem propriedades de…”
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AVALIAÇÃO DE VIABILIDADE DE DETECÇÃO DE DRM EM LLA-B POR CITOMETRIA DE FLUXO MULTIPARAMÉTRICA INDEPENDENTE DE CD19
Published in Hematology, Transfusion and Cell Therapy (01-10-2023)“…A Leucemia Linfoblástica Aguda (LLA) é uma neoplasia de células linfoides imaturas T ou B, sendo a segunda leucemia aguda mais comum no adulto. Acomete cerca…”
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