Search Results - "S Niranjana Murthy, Ashitha"

SHH Signaling as a Key Player in Endometrial Cancer: Unveiling the Correlation with Good Prognosis, Low Proliferation, and Anti-Tumor Immune Milieu by Snijesh, V P, Krishnamurthy, Shivakumar, Bhardwaj, Vipul, Punya, K M, Niranjana Murthy, Ashitha S, Almutadares, Mahmoud, Habhab, Wisam Tahir, Nasser, Khalidah Khalid, Banaganapalli, Babajan, Shaik, Noor Ahmad, Albaqami, Walaa F

“…Endometrial Cancer (EC) is one of the most common gynecological malignancies. Despite its prevalence, molecular pathways, such as the Sonic Hedgehog (SHH)…”
Get full text

Comprehensive in silico mutational-sensitivity analysis of PTEN establishes signature regions implicated in pathogenesis of Autism Spectrum Disorders by S Niranjana Murthy, Ashitha, V Suresh, Raviraj, Nallur B, Ramachandra

“…An extensively studied cancer and Autism Spectrum Disorders (ASD) gene like PTEN provided an exclusive opportunity to map its mutational-landscape, compare and…”
Get full text

Visceral adiposity index and lipid accumulation product as diagnostic markers of metabolic syndrome in South Indians with polycystic ovary syndrome by Naghshband, Zeinab, Kumar, Lakshmi, Mandappa, Sonia, Niranjana Murthy, Ashitha, Malini, Suttur

“…Background: Cardiovascular disease (CVD) is one of the debilitating consequences of polycystic ovary syndrome (PCOS). Early diagnosis of metabolic syndrome…”
Get full text

Assessment and establishment of correlation between reactive oxidation species, citric acid, and fructose level in infertile male individuals: A machine-learning approach by Shemshaki, Golnaz, Murthy, Ashitha, Malini, Suttur

“…Background: Biochemical complexity of seminal plasma and obesity has an important role in male infertility (MI); so far, it has not been possible to provide…”
Get full text

Integrated Functional Analysis Implicates Syndromic and Rare Copy Number Variation Genes as Prominent Molecular Players in Pathogenesis of Autism Spectrum Disorders by Ashitha, S. Niranjana Murthy, Ramachandra, Nallur B.

“…•Identified 105 ‘Prominent CNV regions’ for ASD that were located across 56 loci and 20 chromosomes encompassing 537 genes.•Chromosome 16 contained highest…”
Get full text

Integrated in silico functional analysis predicts autism spectrum disorders to be burdened by deleterious variations within CHD8 core domains and its CHD7-binding motif by S. Niranjana Murthy, Ashitha, Thangalazhi Balakrishnan, Suryanarayanan, Nallur B., Ramachandra

“…Autism spectrum disorder (ASD) is a neurodevelopmental disorder presenting with social and communication deficits, restricted, repetitive behaviours and…”
Get full text

Novel association of PhosphoSerine PHosphatase (PSPH) gene mutations with male infertility identified through whole exome sequencing of South Indians by Shemshaki, Golnaz, Najafi, Mohsen, Niranjana Murthy, Ashitha S., Malini, Suttur S.

“…Male infertility (MI) is mainly caused by spermatogenic failure, and despite long years of assisted reproductive therapy, a significant number of cases remain…”
Get full text

Whole exome sequencing of discordant diseases in Monozygotic twins with Down syndrome reveals mutations for Congenital Heart Defect and epileptic seizures by Niranjana Murthy, Ashitha S., Veerappa, Avinash M., Ramachandra, Nallur B.

“…Discordant phenotypes and diseases in Monozygotic twins (MZ) are always intriguing and genetics is the exclusive reason. Down syndrome is one such disorder,…”
Get full text