Search Results - "S Elzinga, C R"

Virodhamine and CP55,940 modulate cAMP production and IL‐8 release in human bronchial epithelial cells by Gkoumassi, E, Dekkers, B G J, Dröge, M J, Elzinga, C R S, Schmidt, M, Meurs, H, Zaagsma, J, Nelemans, S A

“…Background and purpose: We investigated expression of cannabinoid receptors and the effects of the endogenous cannabinoid virodhamine and the synthetic agonist…”
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D55 LAB METHODOLOGY AND BIOENGINEERING: JUST DO IT: Small Airway Hyperresponsiveness In Precision-Cut Lung Slices Of Patients With Mild To Moderate COPD: Relationship Between Tissue Structure And Function by Meurs, H, Zuidhof, A B, S Elzinga, C R, Smit, M, Oldenburger, A, Bidan, C M, Gosens, R, Timens, W, Maarsingh, H

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Modulation of agonist‐induced phosphoinositide metabolism, Ca2+ signalling and contraction of airway smooth muscle by cyclic AMP‐dependent mechanisms by Hoiting, B.H., Meurs, H., Schuiling, M., Kuipers, R., Elzinga, C.R.S., Zaagsma, J.

“…1 The effects of increased cellular cyclic AMP levels induced by isoprenaline, forskolin and 8‐bromoadenosine 3′:5′‐cyclic monophosphate (8‐Br‐cyclic AMP) on…”
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No evidence for a role of muscarinic M2 receptors in functional antagonism in bovine trachea by Roffel, Ad F., Meurs, Herman, Elzinga, Carolina R.S., Zaagsma, Johan

“…1 The functional antagonism between methacholine‐ or histamine‐induced contraction and β‐adrenoceptor‐mediated relaxation was evaluated in bovine tracheal…”
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Muscarinic M2 receptors in bovine tracheal smooth muscle: discrepancies between binding and function by Roffel, A F, Elzinga, C R, Van Amsterdam, R G, De Zeeuw, R A, Zaagsma, J

“…Previous work showing that AF-DX 116, a cardioselective muscarinic antagonist in functional experiments, does not discriminate between muscarinic receptors in…”
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Characterization of the muscarinic receptor subtype(s) mediating contraction of the guinea‐pig lung strip and inhibition of acetylcholine release in the guinea‐pig trachea with the selective muscarinic receptor antagonist tripitramine by Roffel, Ad F., Davids, Joost H., Elzinga, Carolina R. S., Wolf, Doris, Zaagsma, Johan, Kilbinger, Heinz

“…1 The muscarinic receptor subtypes mediating contraction of the guinea‐pig lung strip and inhibition of the release of acetylcholine from cholinergic vagus…”
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Characterization of the muscarinic receptor subtype involved in phosphoinositide metabolism in bovine tracheal smooth muscle by Roffel, A.F., Meurs, H., Elzinga, C.R.S., Zaagsma, J.

“…1 The muscarinic receptor subtype involved in the methacholine‐induced enhancement of phosphoinositide metabolism in bovine tracheal smooth muscle was…”
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Muscarinic M2 receptors do not participate in the functional antagonism between methacholine and isoprenaline in guinea pig tracheal smooth muscle by Roffel, A F, Meurs, H, Elzinga, C R, Zaagsma, J

“…We investigated whether muscarinic M2 receptors, known to inhibit adenylyl cyclase activity in airway smooth muscle, also inhibit isoprenaline-induced…”
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Cholinergic contraction of the guinea pig lung strip is mediated by muscarinic M2-like receptors by Roffel, A F, Elzinga, C R, Zaagsma, J

“…The muscarinic receptor subtype mediating contraction of the guinea pig lung strip preparation was investigated and compared with that in guinea pig tracheal…”
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Feedforward control of agonist-induced Ca2+ signalling by protein kinase C in airway smooth muscle cells by HOITING, B. H, KUIPERS, R, ELZINGA, C. R. S, ZAAGSMA, J, MEURS, H

“…In isolated bovine tracheal smooth muscle cells, the potent and specific protein kinase C inhibitor GF 109203X caused an inhibition of methacholine-and…”
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Evidence for a direct relationship between phosphoinositide metabolism and airway smooth muscle contraction induced by muscarinic agonists by Meurs, H, Roffel, A F, Postema, J B, Timmermans, A, Elzinga, C R, Kauffman, H F, Zaagsma, J

“…The relationship between bovine tracheal muscle contraction and phosphoinositide metabolism was studied with the muscarinic agonists, methacholine,…”
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Allosteric interactions of three muscarine antagonists at bovine tracheal smooth muscle and cardiac M2 receptors by Roffel, A F, Elzinga, C R, Meurs, H, Zaagsma, J

“…The kinetics of [3H]dexetimide dissociation from muscarine receptors in bovine cardiac left ventricular and tracheal smooth muscle membranes were studied in…”
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Positive cooperative interaction of quaternary anticholinergics with functional muscarinic receptors in bovine tracheal smooth muscle by ROFFEL, A. F, ELZINGA, C. R. S, BELTMAN, W, VAN TINTELEN, E. J. J, ZAAGSMA, J

“…The interaction of quaternary anticholinergics with muscarinic receptors in bovine tracheal smooth muscle strips was investigated because some of these…”
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Selectivity profile of some recent muscarinic antagonists in bovine and guinea-pig trachea and heart by Roffel, A F, Hamstra, J J, Elzinga, C R, Zaagsma, J

“…The functional affinities of some recently developed subtype-selective muscarinic antagonists towards bovine tracheal smooth muscle muscarinic M3 receptors…”
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