Search Results - "S Cho, Steve"
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Targeting Neurovascular Interaction in Retinal Disorders
Published in International journal of molecular sciences (22-02-2020)“…The tightly structured neural retina has a unique vascular network comprised of three interconnected plexuses in the inner retina (and choroid for outer…”
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2
Indocyanine-Green for Fluorescence-Guided Surgery of Brain Tumors: Evidence, Techniques, and Practical Experience
Published in Frontiers in surgery (12-03-2019)“…The primary treatment for brain tumors often involves surgical resection for diagnosis, relief of mass effect, and prolonged survival. In neurosurgery, it is…”
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3
Review of clinical trials in intraoperative molecular imaging during cancer surgery
Published in Journal of biomedical optics (01-12-2019)“…Most solid cancers are treated by surgical resections to reduce the burden of disease. Surgeons often face the challenge of detecting small areas of residual…”
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4
Fibroblast Growth Factor 21 Protects Photoreceptor Function in Type 1 Diabetic Mice
Published in Diabetes (New York, N.Y.) (01-05-2018)“…Retinal neuronal abnormalities occur before vascular changes in diabetic retinopathy. Accumulating experimental evidence suggests that neurons control vascular…”
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5
Dyslipidemia in retinal metabolic disorders
Published in EMBO molecular medicine (01-10-2019)“…The light‐sensitive photoreceptors in the retina are extremely metabolically demanding and have the highest density of mitochondria of any cell in the body…”
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Intraoperative Near-Infrared Optical Contrast Can Localize Brain Metastases
Published in World neurosurgery (01-10-2017)“…Approximately 100,000 brain metastases are diagnosed annually in the United States. Our laboratory has pioneered a novel technique, second window indocyanine…”
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7
Amino acid transporter SLC38A5 regulates developmental and pathological retinal angiogenesis
Published in eLife (01-12-2022)“…Amino acid (AA) metabolism in vascular endothelium is important for sprouting angiogenesis. SLC38A5 (solute carrier family 38 member 5), an AA transporter,…”
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Long-Acting FGF21 Inhibits Retinal Vascular Leakage in In Vivo and In Vitro Models
Published in International journal of molecular sciences (11-02-2020)“…The aim of the current study was to investigate the impact of long-acting fibroblast growth factor 21 (FGF21) on retinal vascular leakage utilizing machine…”
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Photoreceptor glucose metabolism determines normal retinal vascular growth
Published in EMBO molecular medicine (01-01-2018)“…The neural cells and factors determining normal vascular growth are not well defined even though vision‐threatening neovessel growth, a major cause of…”
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10
Free fatty acid receptor 4 activation protects against choroidal neovascularization in mice
Published in Angiogenesis (London) (01-08-2020)“…To examine whether free fatty acid receptor 4 (FFAR4) activation can protect against choroidal neovascularization (CNV), which is a common cause of blindness,…”
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11
The Evolution of 5-Aminolevulinic Acid Fluorescence Visualization: Time for a Headlamp/Loupe Combination
Published in World neurosurgery (01-03-2022)“…The use of 5-aminolevulinic acid (5-ALA) for intraoperative protoporphyrin IX fluorescent imaging in the resection of malignant gliomas has been demonstrated…”
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12
Intraoperative Fluorescent Visualization of Pituitary Adenomas
Published in Neurosurgery clinics of North America (01-10-2019)“…Tumor recurrence in pituitary adenomas is as high as 20% after surgery. Conventional neuronavigation and white light visualization are not sufficiently…”
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13
The Effects of Balloon-Guide Catheters on Outcomes after Mechanical Thrombectomy in Acute Ischemic Strokes : A Meta-Analysis
Published in Journal of Korean Neurosurgical Society (01-07-2019)“…Mechanical thrombectomies with balloon-guide catheters (BGC) are thought to improve successful recanalization rates and to decrease the incidence of distal…”
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14
Delta-Aminolevulinic Acid-Mediated Photodiagnoses in Surgical Oncology: A Historical Review of Clinical Trials
Published in Frontiers in surgery (04-09-2019)“…Fluorescence imaging is an emerging clinical technique for real-time intraoperative visualization of tumors and their boundaries. Though multiple fluorescent…”
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15
Two-Level Anterior Cervical Discectomy and Fusion Performed Using a Three-Dimensional Exoscope
Published in World neurosurgery (01-05-2024)“…Anterior cervical discectomy and fusion (ACDF) is a common neurosurgical procedure. Portions of the procedure, such as the discectomy, foraminotomy, graft…”
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Applications of indocyanine green in brain tumor surgery: review of clinical evidence and emerging technologies
Published in Neurosurgical focus (01-01-2021)“…Indocyanine green (ICG) is a water-soluble dye that was approved by the FDA for biomedical purposes in 1956. Initially used to measure cardiocirculatory and…”
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Intraoperative near-infrared imaging with receptor-specific versus passive delivery of fluorescent agents in pituitary adenomas
Published in Journal of neurosurgery (01-12-2019)“…Intraoperative molecular imaging with tumor-targeted fluorescent dyes can enhance resection rates. In contrast to visible-light fluorophores (e.g.,…”
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18
Regional Hyperexcitability and Chronic Neuropathic Pain Following Spinal Cord Injury
Published in Cellular and molecular neurobiology (01-08-2020)“…Spinal cord injury (SCI) causes maladaptive changes to nociceptive synaptic circuits within the injured spinal cord. Changes also occur at remote regions…”
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Second window ICG predicts gross-total resection and progression-free survival during brain metastasis surgery
Published in Journal of neurosurgery (01-10-2021)“…Metastases are the most common intracranial malignancies and complete resection can provide relief of neurological symptoms and reduce recurrence. The authors'…”
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Folate receptor overexpression can be visualized in real time during pituitary adenoma endoscopic transsphenoidal surgery with near-infrared imaging
Published in Journal of neurosurgery (01-08-2018)“…OBJECTIVE Pituitary adenomas account for approximately 10% of intracranial tumors and have an estimated prevalence of 15%-20% in the general US population…”
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