Search Results - "S A Passos, Livia"
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Innate and adaptive immunity in cardiovascular calcification
Published in Atherosclerosis (01-08-2020)“…Despite the focus placed on cardiovascular research, the prevalence of vascular and valvular calcification is increasing and remains a leading contributor of…”
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Rheumatic Heart Valve Disease Pathophysiology and Underlying Mechanisms
Published in Frontiers in cardiovascular medicine (18-01-2021)“…Rheumatic heart valve disease (RHVD) is a post-infectious sequel of acute rheumatic fever resulting from an abnormal immune response to a streptococcal…”
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3
Systemic cytokines, chemokines and growth factors reveal specific and shared immunological characteristics in infectious cardiomyopathies
Published in Cytokine (Philadelphia, Pa.) (01-12-2021)“…Heart disease is a major cause of death worldwide. Chronic Chagas cardiomyopathy (CCC) caused by infection with Trypanosoma cruzi leading to high mortality in…”
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4
Human CD8+ T Cells Release Extracellular Traps Co-Localized With Cytotoxic Vesicles That Are Associated With Lesion Progression and Severity in Human Leishmaniasis
Published in Frontiers in immunology (08-10-2020)“…Cell death plays a fundamental role in mounting protective and pathogenic immunity. Etosis is a cell death mechanism defined by the release of extracellular…”
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5
Progression of Mitral Regurgitation in Rheumatic Valve Disease: Role of Left Atrial Remodeling
Published in Frontiers in cardiovascular medicine (11-03-2022)“…Mitral regurgitation (MR) is the most common valve abnormality in rheumatic heart disease (RHD) often associated with stenosis. Although the mechanism by which…”
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Integration of Functional Imaging, Cytometry, and Unbiased Proteomics Reveals New Features of Endothelial-to-Mesenchymal Transition in Ischemic Mitral Valve Regurgitation in Human Patients
Published in Frontiers in cardiovascular medicine (12-08-2021)“…Following myocardial infarction, mitral regurgitation (MR) is a common complication. Previous animal studies demonstrated the association of…”
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Proinflammatory Matrix Metalloproteinase-1 Associates With Mitral Valve Leaflet Disruption Following Percutaneous Mitral Valvuloplasty
Published in Frontiers in cardiovascular medicine (20-01-2022)“…Mitral regurgitation (MR) is a major complication of the percutaneous mitral valvuloplasty (PMV). Despite high technical expertise and cumulative experience…”
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Lymphangiogenesis in Rheumatic Heart Valve Disease: A New Factor in the Pathogenic Conundrum
Published in Arteriosclerosis, thrombosis, and vascular biology (01-04-2024)Get full text
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9
CD4+ T cells apoptosis in Plasmodium vivax infection is mediated by activation of both intrinsic and extrinsic pathways
Published in Malaria journal (05-01-2015)“…Reduction in the number of circulating blood lymphocytes (lymphocytopaenia) has been reported during clinical episodes of malaria and is normalized after…”
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10
Can we diagnose acute rheumatic fever early to maximize the success of secondary prophylaxis in rheumatic heart valve disease?
Published in Cardiovascular research (20-07-2022)Get full text
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11
Sortilin enhances fibrosis and calcification in aortic valve disease by inducing interstitial cell heterogeneity
Published in European heart journal (07-03-2023)“…Abstract Aims Calcific aortic valve disease (CAVD) is the most common valve disease, which consists of a chronic interplay of inflammation, fibrosis, and…”
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12
Proprotein Convertase Subtilisin/Kexin 9 (PCSK9) Promotes Macrophage Activation via LDL Receptor-Independent Mechanisms
Published in Circulation research (11-11-2022)“…Activated macrophages contribute to the pathogenesis of vascular disease. Vein graft failure is a major clinical problem with limited therapeutic options…”
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13
Prothymosin Alpha: A Novel Contributor to Estradiol Receptor Alpha–Mediated CD8+ T-Cell Pathogenic Responses and Recognition of Type 1 Collagen in Rheumatic Heart Valve Disease
Published in Circulation (New York, N.Y.) (15-02-2022)“…Rheumatic heart valve disease (RHVD) is a leading cause of cardiovascular death in low- and middle-income countries and affects predominantly women. The…”
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14
Co‐infection with distinct Trypanosoma cruzi strains induces an activated immune response in human monocytes
Published in Parasite immunology (01-11-2019)“…Aims The aim of the study was to evaluate the immune response triggered by the first contact of human monocytes with two T cruzi strains from distinct discrete…”
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Mitral Regurgitation After Percutaneous Mitral Valvuloplasty: Insights Into Mechanisms and Impact on Clinical Outcomes
Published in JACC. Cardiovascular imaging (01-12-2020)“…The aim of this study was to assess the incidence, mechanisms, and outcomes of mitral regurgitation (MR) after percutaneous mitral valvuloplasty (PMV)…”
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16
Histopathological Characterization of Mitral Valvular Lesions from Patients with Rheumatic Heart Disease
Published in Arquivos brasileiros de cardiologia (01-03-2021)“…The underlying mechanisms by which rheumatic heart disease (RHD) lead to severe valve dysfunction are not completely understood. The present study evaluated…”
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17
Raising awareness for rheumatic mitral valve disease
Published in Global Cardiology Science & Practice (30-11-2020)“…Rheumatic heart disease (RHD) is a major burden in low- to mid-income countries, where each year it accounts for over a million premature deaths associated…”
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Caracterização Histológica das Lesões da Valva Mitral de Pacientes com Cardiopatia Reumática
Published in Arquivos brasileiros de cardiologia (01-03-2021)“…Resumo Fundamentos: Os mecanismos subjacentes pelos quais a doença cardíaca reumática (DCR) levam à disfunção valvar grave não são totalmente compreendidos…”
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Caracterização Histológica das Lesões da Valva Mitral de Pacientes com Cardiopatia Reumática
Published in Arquivos brasileiros de cardiologia (03-03-2021)Get full text
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20
CD4 super(+) T cells apoptosis in Plasmodium vivax infection is mediated by activation of both intrinsic and extrinsic pathways
Published in Malaria journal (01-01-2015)“…Background: Reduction in the number of circulating blood lymphocytes (lymphocytopaenia) has been reported during clinical episodes of malaria and is normalized…”
Get full text
Journal Article