Search Results - "Şensoy, Özge"
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The single nucleotide β -arrestin2 variant, A248T, resembles dynamical properties of activated arrestin
Published in Turkish journal of chemistry (01-01-2020)“…β -arrestins are responsible for termination of G protein-coupled receptor (GPCR)-mediated signaling. Association of single nucleotide variants with onset of…”
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Synthesis, Structural Investigations, DNA/BSA Interactions, Molecular Docking Studies, and Anticancer Activity of a New 1,4-Disubstituted 1,2,3-Triazole Derivative
Published in ACS omega (05-09-2023)“…We report herein a new 1,2,3-triazole derivative, namely, 4-((1-(3,4-dichlorophenyl)-1H-1,2,3-triazol-4-yl)methoxy)-2-hydroxybenzaldehyde, which was…”
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A New Ratio-Metric pH Probe, “ThiAKS Green” for Live-Cell pH Measurements
Published in Photonic sensors (Berlin) (01-03-2023)“…Deviation of the H + concentration from optimum values within the organelles is closely associated with irregular cellular functions that cause the onset of…”
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Perturbation–Response Scanning Reveals Key Residues for Allosteric Control in Hsp70
Published in Journal of chemical information and modeling (26-06-2017)“…Hsp70 molecular chaperones play an important role in maintaining cellular homeostasis, and are implicated in a wide array of cellular processes, including…”
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Short‐term impact of a combination intervention on family cohesion: Results from a pilot cluster‐randomized clinical trial in Northern Ghana
Published in Journal of research on adolescence (01-09-2024)“…Child labor remains a concern in sub‐Saharan Africa. Yet, evidence‐based preventive efforts are limited. We analyzed longitudinal data from Ghanaian adolescent…”
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Perturb-Scan-Pull: A Novel Method Facilitating Conformational Transitions in Proteins
Published in Journal of chemical theory and computation (09-06-2020)“…Conformational transitions in proteins facilitate precise physiological functions. Therefore, it is crucial to understand the mechanisms underlying these…”
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Self-esteem and self-concept as correlates of life satisfaction and attitudes toward school among Ghanaian girls
Published in Journal of research on adolescence (01-03-2024)“…During adolescence, youth experience several physical, psychosocial, and cognitive changes. Self-esteem and self-concept are identified as protective factors…”
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The long-term effects of a family based economic empowerment intervention (Suubi+Adherence) on suppression of HIV viral loads among adolescents living with HIV in southern Uganda: Findings from 5-year cluster randomized trial
Published in PloS one (10-02-2020)“…The rapid scale-up of HIV therapy across Africa has failed to adequately engage adolescents living with HIV (ALWHIV). Retention and viral suppression for this…”
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The longitudinal impact of an evidence‐based multiple family group intervention (Amaka Amasanyufu) on oppositional defiant disorder and impaired functioning among children in Uganda: analysis of a cluster randomized trial from the SMART Africa‐Uganda scale‐up study (2016–2022)
Published in Journal of child psychology and psychiatry (01-11-2022)“…Background Oppositional Defiant Disorders (ODDs) and other Disruptive Behavior Disorders (DBDs) are common among children and adolescents in poverty‐impacted…”
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Utilization of Biased G Protein-Coupled Receptor Signaling towards Development of Safer and Personalized Therapeutics
Published in Molecules (Basel, Switzerland) (29-05-2019)“…G protein-coupled receptors (GPCRs) are involved in a wide variety of physiological processes. Therefore, approximately 40% of currently prescribed drugs have…”
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Short-Term Impact of “Amaka Amasanyufu” Multiple Family Group Intervention on Mental Health Functioning of Children With Disruptive Behavior Disorders in Uganda
Published in Journal of the American Academy of Child and Adolescent Psychiatry (01-07-2023)“…We evaluate the mid-intervention (8 weeks) and short-term (16 weeks) impact of a culturally adapted multiple family group (MFG) intervention, “Amaka…”
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"I decided in my heart I have to complete the sessions": A qualitative study on the acceptability of an evidence-based HIV risk reduction intervention among women engaged in sex work in Uganda
Published in PloS one (12-01-2023)“…The HIV burden remains a critical public health concern and women engaged in sex work [WESW] are at significantly higher risk compared to the general adult…”
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From “4Rs and 2Ss” to “Amaka Amasanyufu” (Happy Families): Adapting a U.S.‐based Evidence‐Based Intervention to the Uganda Context
Published in Family process (01-12-2020)“…In Uganda, one in five children presents mental health challenges, including disruptive behavior disorders (DBDs). DBDs can persist through adulthood and…”
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Bridges-Round 2: A study protocol to examine the longitudinal HIV risk prevention and care continuum outcomes among orphaned youth transitioning to young adulthood
Published in PloS one (10-05-2023)“…Youth orphaned by HIV in sub-Saharan Africa experience immense hardships including social disadvantage, adverse childhood events and limited economic…”
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Social and Economic Equity and Family Cohesion as Potential Protective Factors from Depression Among Adolescents Living with HIV in Uganda
Published in AIDS and behavior (01-09-2020)“…Adolescents living with HIV in Uganda are impacted by poverty and face a number of health and social challenges including access to medication, health…”
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FbpA iron storage and release are governed by periplasmic microenvironments
Published in Physical chemistry chemical physics : PCCP (2017)“…Ferric binding protein (FbpA) is part of an elaborate iron piracy mechanism evolved in Gram-negative bacteria, shuttling iron in the periplasmic space, from…”
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The impact of COVID-19 changes and disruptions on generalized anxiety disorder among young adults living with HIV (YLHIV) in Uganda
Published in Journal of health psychology (01-05-2024)“…In the context of the COVID-19 pandemic, we investigated associations between specific COVID-19-related changes and its impact on generalized anxiety disorder…”
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The longitudinal impact of an evidence-based multiple family group intervention (Amaka Amasanyufu) on family cohesion among children in Uganda: Analysis of the cluster randomized SMART Africa-Uganda scale-up study (2016-2022)
Published in Family process (18-05-2024)“…Family functioning plays a critical role in childhood disruptive behavior disorders (The Family Journal, 2003, 11(1), 33-41; Research in Nursing and Health,…”
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" ANZANSI Program Taught Me Many Things in Life ": Families' Experiences with a Combination Intervention to Prevent Adolescent Girls' Unaccompanied Migration for Labor
Published in International journal of environmental research and public health (13-10-2022)“…Approximately 160 million children work as child laborers globally, 39% of whom are female. Ghana is one of the countries with the highest rates of child…”
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