Search Results - "Sőnksen, Peter H"

The Growth Hormone/Insulin-Like Growth Factor-I Axis in Exercise and Sport by Gibney, James, Healy, Marie-Louise, Sönksen, Peter H

“…The syndrome of adult GH deficiency and the effects of GH replacement therapy provide a useful model with which to study the effects of the GH/IGF-I axis on…”
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The effects of recombinant human insulin‐like growth factor‐1/insulin‐like growth factor binding protein‐3 administration on lipid and carbohydrate metabolism in recreational athletes by Guha, Nishan, Nevitt, Simon P., Francis, Michael, Böhning, Walailuck, Böhning, Dankmar, Sönksen, Peter H., Holt, Richard I. G.

“…Objective Previous studies suggested that recombinant human IGF‐1 (rhIGF‐1) administration affects carbohydrate and lipid metabolism in healthy people and in…”
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Statistical methodology for age-adjustment of the GH-2000 score detecting growth hormone misuse by Böhning, Dankmar, Böhning, Walailuck, Guha, Nishan, Cowan, David A, Sönksen, Peter H, Holt, Richard I G

“…The GH-2000 score has been developed as a powerful and unique technique for the detection of growth hormone misuse by sportsmen and women. The score depends…”
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The Effects of Growth Hormone and/or Testosterone in Healthy Elderly Men: A Randomized Controlled Trial by Giannoulis, Manthos G., Sonksen, Peter H., Umpleby, Margot, Breen, Louise, Pentecost, Claire, Whyte, Martin, McMillan, Carolyn V., Bradley, Clare, Martin, Finbarr C.

“…Context: Declines in GH and testosterone (Te) secretion may contribute to the detrimental aging changes of elderly men. Objective: To assess the effects of…”
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Erratum to: Statistical methodology for age-adjustment of the GH-2000 score detecting growth hormone misuse by Böhning, Dankmar, Böhning, Walailuck, Guha, Nishan, Cowan, David A, Sönksen, Peter H, Holt, Richard I G

“…After publication of the original article [1], it came to the authors' attention that there was an error affecting equation (7). A correction to this equation…”
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Novel markers to detect recombinant human insulin‐like growth factor‐I (rhIGF‐I)/rhIGF binding protein‐3 (rhIGFBP‐3) misuse in athletes by Holt, Richard I. G., Guha, Nishan, Böhning, Walailuck, Bartlett, Christiaan, Cowan, David A., Sönksen, Peter H., Böhning, Dankmar

“…Insulin‐like growth factor‐I (IGF‐I) is abused by elite athletes for its metabolic and anabolic effects. We have previously shown that it is possible to detect…”
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The history of doping and growth hormone abuse in sport by Holt, Richard I.G, Erotokritou-Mulligan, Ioulietta, Sönksen, Peter H

“…Abstract The earliest records of doping in sport come from the Ancient Olympics games when athletes are reported to have taken figs to improve their…”
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The Effect of Sports Injury on Insulin-Like Growth Factor-I and Type 3 Procollagen: Implications for Detection of Growth Hormone Abuse in Athletes by Erotokritou-Mulligan, Ioulietta, Bassett, E. Eryl, Bartlett, Christiaan, Cowan, David, McHugh, Cathy, Seah, Rick, Curtis, Benjamin, Wells, Victoria, Harrison, Kate, Sönksen, Peter H., Holt, Richard I. G.

“…Context: A method to detect exogenously administered growth hormone (GH) based on the measurement of two GH-dependent markers, IGF-I and type 3 procollagen…”
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Insulin-like growth factor-I (IGF-I) misuse in athletes and potential methods for detection by Guha, Nishan, Cowan, David A., Sönksen, Peter H., Holt, Richard I. G.

“…To athletes, insulin-like growth factor-I (IGF-I) is an attractive performance-enhancing drug, particularly as an alternative to growth hormone (GH) because…”
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A correction to the age-adjustment of the GH-2000 score used in the detection of growth hormone misuse by Böhning, Dankmar, Böhning, Walailuck, Guha, Nishan, Cowan, David A, Bartlett, Christiaan, Sönksen, Peter H, Holt, Richard I G

“…The GH-2000 biomarker test has been introduced by the World Anti-Doping Agency as a method of detecting growth hormone misuse in professional sport. The test…”
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The development of decision limits for the GH-2000 detection methodology using additional insulin-like growth factor-I and amino-terminal pro-peptide of type III collagen assays by Holt, Richard I. G., Böhning, Walailuck, Guha, Nishan, Bartlett, Christiaan, Cowan, David A., Giraud, Sylvain, Bassett, E. Eryl, Sönksen, Peter H., Böhning, Dankmar

“…The GH‐2000 and GH‐2004 projects have developed a method for detecting GH misuse based on measuring insulin‐like growth factor‐I (IGF‐I) and the amino‐terminal…”
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Challenges in Detecting the Abuse of Growth Hormone in Sport by McHugh, Cathy M, Park, Roderick T, Sonksen, Peter H, Holt, Richard I.G

“…Growth hormone (GH) is reputed to be in widespread use in the sporting arena as a performance-enhancing agent and is on the list of banned substances published…”
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Serum Insulin-Like Growth Factor-I and Pro-Collagen Type III N-Terminal Peptide in Adolescent Elite Athletes: Implications for the Detection of Growth Hormone Abuse in Sport by Guha, Nishan, Erotokritou-Mulligan, Ioulietta, Burford, Caroline, Strobridge, Gail, Brigg, Joanna, Drake, Tamsin, Bassett, E. Eryl, Cowan, David, Bartlett, Christiaan, Sönksen, Peter H., Holt, Richard I. G.

“…Context: A method based on two GH-dependent markers, IGF-I and pro-collagen type III N-terminal peptide (P-III-P), has been devised to detect exogenously…”
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Influence of ethnicity on IGF-I and procollagen III peptide (P-III-P) in elite athletes and its effect on the ability to detect GH abuse by Erotokritou-Mulligan, Ioulietta, Bassett, E. Eryl, Cowan, David A., Bartlett, Christiaan, McHugh, Cathy, Sönksen, Peter H., Holt, Richard I. G.

“…Summary Context  A method based on the two GH dependent markers, IGF‐I and procollagen III peptide (P‐III‐P) has been proposed to detect exogenously…”
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The physiology of growth hormone and sport by Widdowson, W. Matthew, Healy, Marie-Louise, Sönksen, Peter H, Gibney, James

“…ABSTRACT The growth hormone (GH)/ insulin-like growth factor-I (IGF-I) axis exerts short-and long-term metabolic effects that are potentially important during…”
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The use of growth hormone (GH)-dependent markers in the detection of GH abuse in sport: Physiological intra-individual variation of IGF-I, type 3 pro-collagen (P-III-P) and the GH-2000 detection score by Erotokritou-Mulligan, Ioulietta, Eryl Bassett, E., Cowan, David A., Bartlett, Christiaan, Milward, Polly, Sartorio, Alessandro, Sönksen, Peter H., Holt, Richard I. G.

“…Summary Background  Growth Hormone is abused by athletes for its lipolytic and anabolic properties. Its use is prohibited by the World Anti‐Doping Agency. The…”
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The Effects of Growth Hormone and/or Testosterone on Whole Body Protein Kinetics and Skeletal Muscle Gene Expression in Healthy Elderly Men: A Randomized Controlled Trial by Giannoulis, Manthos G., Jackson, Nicola, Shojaee-Moradie, Fariba, Nair, K. Sreekumaran, Sonksen, Peter H., Martin, Finbarr C., Umpleby, A. Margot

“…Context: Alterations of protein turnover may contribute to the progressive decline of muscle mass with aging. Objective: Our objective was to examine the…”
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Validation of the growth hormone (GH)-dependent marker method of detecting GH abuse in sport through the use of independent data sets by Erotokritou-Mulligan, Ioulietta, Bassett, E. Eryl, Kniess, Astrid, Sönksen, Peter H, Holt, Richard I.G

“…Abstract Context The detection of exogenously administered growth hormone (GH) poses a formidable challenge but a detection method based on the measurement of…”
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The GH-2004 project: the response of IGF1 and type III pro-collagen to the administration of exogenous GH in non-Caucasian amateur athletes by Holt, Richard I G, Erotokritou-Mulligan, Ioulietta, McHugh, Cathy, Bassett, E Eryl, Bartlett, Christiaan, Fityan, Adam, Bacon, Jenny L, Cowan, David A, Sönksen, Peter H

“…ContextThe GH-2000 team proposed a method based on IGF1 and type III pro-collagen (P-III-P) to detect exogenously administered GH. As previous studies involved…”
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Toward the Development of a Test for Growth Hormone (GH) Abuse: A Study of Extreme Physiological Ranges of GH-Dependent Markers in 813 Elite Athletes in the Postcompetition Setting by Healy, Marie-Louise, Dall, Rolf, Gibney, James, Bassett, Eryl, Ehrnborg, Christer, Pentecost, Claire, Rosen, Thord, Cittadini, Antonio, Baxter, Robert C., Sönksen, Peter H.

“…There is a need to develop a test to detect GH abuse by elite athletes. Measured levels of GH in blood or urine, however, provide little information on the…”
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