Search Results - "Sırma Ekmekçi, Sema"
-
1
Investigation of Gene Expressions of Myeloma Cells in the Bone Marrow of Multiple Myeloma Patients by Transcriptome Analysis
Published in Balkan medical journal (01-01-2019)“…Multiple myeloma is a plasma cell dyscrasia characterized by transformation of B cells into malignant cells. Although there are data regarding the molecular…”
Get full text
Journal Article -
2
High MN1 expression increases the in vitro clonogenic activity of primary mouse B-cells
Published in Leukemia research (01-08-2015)“…Highlights • MN1 expression is significantly increased in TEL–AML1+ B-ALL patients bone marrow. • MN1 and AML1 expression show significant correlation in B-ALL…”
Get full text
Journal Article -
3
Association between endothelial nitric oxide synthase intron 4a/b polymorphism and aortic dissection
Published in Türk Kardiyoloji Derneği arşivi (01-01-2014)“…The genetic risk factors that contribute to the risk of developing aortic dissection (AD) have been studied. We assessed the association of endothelial nitric…”
Get full text
Journal Article -
4
Metagenomic analysis of black-stained plaques in permanent dentition
Published in Archives of oral biology (01-08-2021)“…•Black stain has multimicrobial etiology and related with low caries.•Capnocytophaga, Corynebacterium, Neisseria spp. were higher in black stain.•Next…”
Get full text
Journal Article -
5
LEF1 Induces DHRS2 Gene Expression in Human Acute Leukemia Jurkat T-Cells
Published in Turkish journal of haematology (01-01-2020)“…Objective: T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive disease resulting from the accumulation of genetic changes that affect the development…”
Get full text
Journal Article -
6
DHRS2 is a potential marker of breast cancer metastasis
Published in Gene reports (01-12-2021)“…Although breast cancer treatment success has increased, biomarkers are still important. The dehydrogenase/reductase DHRS2 has a role in the metabolic and…”
Get full text
Journal Article -
7
Low dose monoethyl phthalate (MEP) exposure triggers proliferation by activating PDX-1 at 1.1B4 human pancreatic beta cells
Published in Food and chemical toxicology (01-07-2016)“…Phthalate plasticizers used in a wide range of common plastic products are released into the environment and may pose a risk of increased incidence of type 2…”
Get full text
Journal Article -
8
Upregulation of SPINK2 in acute myeloid leukemia
Published in Advances in laboratory medicine (11-04-2023)“…Acute myeloid leukemia (AML) is a highly heterogeneous disease. Although patients can be classified into risk groups based on their genetic changes, the…”
Get full text
Journal Article -
9
Mitochondrial mutations in patients with congenital heart defects by next generation sequencing technology
Published in Cardiology in the young (01-04-2015)“…It has been shown that mitochondrial deoxyribo nucleic acid mutations may play an important role in the development of cardiomyopathy, and various types of…”
Get more information
Journal Article -
10
Elevación de SPINK2 en leucemia mieloide aguda
Published in Advances in laboratory medicine (11-04-2023)“…Resumen Objectivos La leucemia mieloide aguda (AML, por sus siglas en inglés) es una enfermedad muy heterogénea. Aunque se puede clasificar a los pacientes en…”
Get full text
Journal Article -
11
Serum sirtuin 1 protein as a potential biomarker for type 2 diabetes: Increased expression of sirtuin 1 and the correlation with microRNAs
Published in Journal of research in medical sciences (01-01-2019)“…Background: Type 2 diabetes (T2DM) is characterized by hyperglycemia and insulin deficiency. Sirtuin 1 (SIRT1), serving as a deacetylase, is critical in the…”
Get full text
Journal Article -
12
A Potential Target for Treating Acute Myeloid Leukemia: XBP1 involved in Endoplasmic Reticulum Stress
Published in Türk onkoloji dergisi (2023)Get full text
Journal Article -
13
Association of Pro-apoptotic Bad Gene Expression Changes with Benign Thyroid Nodules
Published in In vivo (Athens) (01-05-2018)“…This study aimed to investigate the role of the mitochondrial apoptotic pathway in benign thyroid nodules. Paired samples of nodular and normal tissues were…”
Get full text
Journal Article -
14
Small ubiquitin-related modifier (SUMO) 3 and SUMO4 gene polymorphisms in Parkinson's disease
Published in Neurological research (New York) (02-06-2020)“…Objectives: The ubiquitin/proteasome system is one of the main axes of the pathogenesis of Parkinson's disease (PD). Small ubiquitin-related modifier (SUMO)…”
Get full text
Journal Article -
15
SET Oncogene is Upregulated in Pediatric Acute Lymphoblastic Leukemia
Published in Tumori (01-03-2012)“…Aims and background The SET gene is a target of chromosomal translocations in acute leukemia and encodes a widely expressed multifunctional phosphoprotein. It…”
Get full text
Journal Article -
16
Association of Pro-apoptotic Bad Gene Expression Changes with Benign Thyroid Nodules
Published in In vivo (Athens) (03-05-2018)“…Background/Aim: This study aimed to investigate the role of the mitochondrial apoptotic pathway in benign thyroid nodules. Materials and Methods: Paired…”
Get full text
Journal Article -
17
SET oncogene is upregulated in pediatric acute lymphoblastic leukemia
Published in Tumori (01-03-2012)“…AIMS AND BACKGROUNDThe SET gene is a target of chromosomal translocations in acute leukemia and encodes a widely expressed multifunctional phosphoprotein. It…”
Get full text
Journal Article -
18
-
19
Identification of potential target genes of ROR-alpha in THP1 and HUVEC cell lines
Published in Experimental cell research (01-04-2017)“…ROR-alpha is a nuclear receptor, activity of which can be modulated by natural or synthetic ligands. Due to its possible involvement in, and potential…”
Get full text
Journal Article -
20
Phenotypic variability including Behçet's disease-like manifestations in DADA2 patients due to a homozygous c.973-2A>G splice site mutation
Published in Clinical and experimental rheumatology (01-11-2019)“…To describe phenotypic and functional characteristics of patients with the homozygous c.973-2A>G splice site mutation in the adenosine deaminase 2 (ADA2) gene…”
Get full text
Journal Article