Search Results - "Sütterlin, Rosmarie"
-
1
Lewy pathology in Parkinson’s disease consists of crowded organelles and lipid membranes
Published in Nature neuroscience (01-07-2019)“…Parkinson’s disease, the most common age-related movement disorder, is a progressive neurodegenerative disease with unclear etiology. Key neuropathological…”
Get full text
Journal Article -
2
Single and few cell analysis for correlative light microscopy, metabolomics, and targeted proteomics
Published in Lab on a chip (10-09-2024)“…The interactions of proteins, membranes, nucleic acid, and metabolites shape a cell's phenotype. These interactions are stochastic, and each cell develops…”
Get more information
Journal Article -
3
“Differential Visual Proteomics”: Enabling the Proteome-Wide Comparison of Protein Structures of Single-Cells
Published in Journal of proteome research (06-09-2019)“…Proteins are involved in all tasks of life, and their characterization is essential to understand the underlying mechanisms of biological processes. We present…”
Get full text
Journal Article -
4
Cryo-EM analysis of homodimeric full-length LRRK2 and LRRK1 protein complexes
Published in Scientific reports (17-08-2017)“…Leucine-rich repeat kinase 2 (LRRK2) is a large multidomain protein implicated in the pathogenesis of both familial and sporadic Parkinson’s disease (PD), and…”
Get full text
Journal Article -
5
Transwell‐Based Microfluidic Platform for High‐Resolution Imaging of Airway Tissues
Published in Advanced materials technologies (01-10-2024)“…Transwell‐based airway models have become increasingly important in studying the effects of respiratory diseases and drug treatment at the air–liquid interface…”
Get full text
Journal Article -
6
Pseudomonas aeruginosa breaches respiratory epithelia through goblet cell invasion in a microtissue model
Published in Nature microbiology (01-07-2024)“…Pseudomonas aeruginosa , a leading cause of severe hospital-acquired pneumonia, causes infections with up to 50% mortality rates in mechanically ventilated…”
Get full text
Journal Article -
7
An antiparallel actin dimer is associated with the endocytic pathway in mammalian cells
Published in Journal of structural biology (2012)“…The dynamic rearrangement of the actin cytoskeleton plays a key role in several cellular processes such as cell motility, endocytosis, RNA processing and…”
Get full text
Journal Article -
8
Functional differentiation of stem cell-derived neurons from different murine backgrounds
Published in Frontiers in cellular neuroscience (20-02-2014)“…Murine stem cell-derived neurons have been used to study a wide variety of neuropsychiatric diseases with a hereditary component, ranging from autism to…”
Get full text
Journal Article -
9
Reduced synaptic activity in neuronal networks derived from embryonic stem cells of murine Rett syndrome model
Published in Frontiers in cellular neuroscience (26-03-2014)“…Neurodevelopmental diseases such as the Rett syndrome (RTT) have received renewed attention, since the mechanisms involved may underlie a broad range of…”
Get full text
Journal Article -
10
The Structural Basis for the Intrinsic Disorder of the Actin Filament: The "Lateral Slipping" Model
Published in The Journal of cell biology (01-11-1991)“…Three-dimensional (3-D) helical reconstructions computed from electron micrographs of negatively stained dispersed F-actin filaments invariably revealed two…”
Get full text
Journal Article -
11
Punch-wounded, fibroblast populated collagen matrices: a novel approach for studying cytoskeletal changes in three dimensions by confocal laser scanning microscopy
Published in European journal of cell biology (01-03-1997)“…Depending on growth conditions and cell type, collagen matrices populated with viable cells, i.e. commonly with fibroblasts, contract in a manner resembling…”
Get more information
Journal Article -
12
Specific types of prosomes distribute differentially between intermediate and actin filaments in epithelial, fibroblastic and muscle cells
Published in European journal of cell biology (01-06-2000)“…First observed as components of non-translated mRNP complexes, prosomes harbour RNase and several proteinase activities; they are also the central constituent…”
Get full text
Journal Article