Search Results - "Sültmann, H"

Recommendations for a practical implementation of circulating tumor DNA mutation testing in metastatic non-small-cell lung cancer by Heitzer, E., van den Broek, D., Denis, M.G., Hofman, P., Hubank, M., Mouliere, F., Paz-Ares, L., Schuuring, E., Sültmann, H., Vainer, G., Verstraaten, E., de Visser, L., Cortinovis, D.

“…Liquid biopsy (LB) is a rapidly evolving diagnostic tool for precision oncology that has recently found its way into routine practice as an adjunct to tissue…”
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The bromodomain protein BRD4 regulates the KEAP1/NRF2-dependent oxidative stress response by Hussong, M, Börno, S T, Kerick, M, Wunderlich, A, Franz, A, Sültmann, H, Timmermann, B, Lehrach, H, Hirsch-Kauffmann, M, Schweiger, M R

“…The epigenetic sensor BRD4 (bromodomain protein 4) is a potent target for anti-cancer therapies. To study the transcriptional impact of BRD4 in cancer, we…”
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Overexpression of TMPRSS2:ERG variants activates TGF-β signaling and promotes invasion of prostate cancer cells by Ratz, L, Laible, M, Altevogt, P, Klauck, S.M, Sültmann, H

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PARP inhibition in BRCA2-mutated prostate cancer by Nientiedt, C., Tolstov, Y., Volckmar, A.-L., Endris, V., Bonekamp, D., Haberkorn, U., Jäger, D., Sültmann, H., Stenzinger, A., Hohenfellner, M., Grüllich, C., Duensing, S.

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Reduced expression of vacuole membrane protein 1 affects the invasion capacity of tumor cells by Sauermann, M, Sahin, Ö, Sültmann, H, Hahne, F, Blaszkiewicz, S, Majety, M, Zatloukal, K, Füzesi, L, Poustka, A, Wiemann, S, Arlt, D

“…Vacuole membrane protein 1 (Vmp1) is described as a cancer-relevant cell cycle modulator, but the function of this protein and its mode of action in tumor…”
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Subtractive gene expression profiling of articular cartilage and mesenchymal stem cells: serpins as cartilage-relevant differentiation markers by Boeuf, S., Ph.D, Steck, E., Ph.D, Pelttari, K, Hennig, T, Buneß, A, Benz, K, Witte, D., M.D, Sültmann, H., Ph.D, Poustka, A., Ph.D, Richter, W., Ph.D

“…Summary Objective Mesenchymal stem cells (MSCs) are a population of cells broadly discussed to support cartilage repair. The differentiation of MSCs into…”
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Transcription alterations of members of the ubiquitin-proteasome network in prostate carcinoma by Hellwinkel, O J C, Asong, L E, Rogmann, J-P, Sültmann, H, Wagner, C, Schlomm, T, Eichelberg, C

“…The purpose of this work was to investigate the role of the ubiquitin–proteasome network (UPN) in prostate cancer (PCA) and to elicit potential markers for…”
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Nonlinkage of major histocompatibility complex class I and class II loci in bony fishes by Sato, A, Figueroa, F, Murray, B W, Málaga-Trillo, E, Zaleska-Rutczynska, Z, Sültmann, H, Toyosawa, S, Wedekind, C, Steck, N, Klein, J

“…In tetrapods, the functional (classical) class I and class II B loci of the major histocompatibility complex (Mhc) are tightly linked in a single chromosomal…”
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331 The Microenvironment Regulates Responses to Hepsin Overexpression in Prostate Cancer Cells by Wittig, R, Wittig-Blaich, S.M, Kacprzyk, L.A, Bewerunge-Hudler, M, Eismann, T, Schrader, M, Strauss, W.S.L, Mertens, D, Sültmann, H

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Discrimination of direct and indirect interactions in a network of regulatory effects by Tresch, Achim, Beissbarth, T, Sültmann, H, Kuner, R, Poustka, A, Buness, A

“…The matter of concern are algorithms for the discrimination of direct from indirect regulatory effects from an interaction graph built up by error-prone…”
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Metastases and multiple myeloma generate distinct transcriptional footprints in osteocytes in vivo by Eisenberger, S, Ackermann, K, Voggenreiter, G, Sültmann, H, Kasperk, C, Pyerin, W

“…Osteocytes are the most abundant bone cells, playing important roles in tissue maintenance. Little is known of how they react in vivo to cancer stress. Here we…”
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A Contig Map of the Mhc Class I Genomic Region in the Zebrafish Reveals Ancient Synteny by Michalova, Vera, Murray, Brent W, Sultmann, Holger, Klein, Jan

“…In contrast to the human and mouse Mhc, in which the clusters of class I and class II loci reside in close vicinity to one another, in the zebrafish, Danio…”
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Identification of Seven Genes in the Major Histocompatibility Complex Class I Region of the Zebrafish by Sültmann, H, Murray, B W, Klein, J

“…Physical linkage of genes whose products are involved in similar physiological pathways may have functional significance. The identification of conserved gene…”
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333 Identification of drug-associated proteins in NSCLC xenograft models by reverse phase protein arrays by Hülsmann, H, Bender, C, Rolff, J, Fichtner, I, Herwig, R, Sültmann, H, Kuner, R

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Analysis of a 26-kb region linked to the Mhc in zebrafish: genomic organization of the proteasome component beta/transporter associated with antigen processing-2 gene cluster and identification of five new proteasome beta subunit genes by Murray, B W, Sültmann, H, Klein, J

“…Sequencing of zebrafish (Danio rerio) bacterial artificial chromosome and P1 artificial chromosome genomic clone fragments and of cDNA clones has led to the…”
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761 Reverse-phase protein arrays as a tool to discover mutation-associated alterations in cell signaling pathways by Starmann, J, Blaich, S, Bender, C, Armbruster, H, Mannsperger, H, Lange, B, Korf, U, Sültmann, H

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Identification and Linkage of the Proteasome Activator Complex PA28 Subunit Genes in Zebrafish by Murray, B W, Sültmann, H, Klein, J

“…PA28 is an activator of the latent 20S proteasome, a large multisubunit complex involved in intracellular proteolysis. Two forms of hexameric PA28 have been…”
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Major histocompatibility complex class II A genes in cichlid fishes: identification, expression, linkage relationships, and haplotype variation by Murray, B W, Shintani, S, Sültmann, H, Klein, J

“…Two cichlid species, the haplochromine Aulonocara hansbaenschi and the tilapiine Oreochromis niloticus, were used to study the major histocompatibility complex…”
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119 - Overexpression of TMPRSS2:ERG variants activates TGF-β signaling and promotes invasion of prostate cancer cells by Ratz, L., Laible, M., Altevogt, P., Klauck, S.M., Sültmann, H.

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65P Blood cytokine changes in patients with advanced NSCLC receiving immunotherapy by Schindler, H.L., Lusky, F., Gaissmaier, L., Daniello, L., Elshiaty, M., Bozorgmehr, F., Kuon, J., Shah, R., Schneider, M., Eichhorn, F., Baum, P., Angeles, A., Janke, F., Kriegsmann, M., Kazdal, D., Stenzinger, A., Sültmann, H., Thomas, M., Christopoulos, P.

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