Search Results - "Sørensen, Anita L"
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A lipodystrophy-causing lamin A mutant alters conformation and epigenetic regulation of the anti-adipogenic MIR335 locus
Published in The Journal of cell biology (04-09-2017)“…Mutations in the ( ) gene-encoding nuclear LMNA cause laminopathies, which include partial lipodystrophies associated with metabolic syndromes. The…”
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2
Induction of dedifferentiation, genomewide transcriptional programming, and epigenetic reprogramming by extracts of carcinoma and embryonic stem cells
Published in Molecular biology of the cell (01-12-2005)“…Functional reprogramming of a differentiated cell toward pluripotency may have long-term applications in regenerative medicine. We report the induction of…”
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3
Younger Dryas ice margin retreat in Greenland: new evidence from southwestern Greenland
Published in Climate of the past (04-03-2021)“…To date the final stage in deglaciation of the Greenland shelf, when a contiguous ice sheet margin on the inner shelf transitioned to outlet glaciers in…”
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CpG Methylation Profiles of Endothelial Cell‐Specific Gene Promoter Regions in Adipose Tissue Stem Cells Suggest Limited Differentiation Potential Toward the Endothelial Cell Lineage
Published in Stem cells (Dayton, Ohio) (01-04-2007)“…In vivo endothelial commitment of adipose stem cells (ASCs) has scarcely been reported, and controversy remains on the contribution of ASCs to vascularization…”
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Chrom3D: three-dimensional genome modeling from Hi-C and nuclear lamin-genome contacts
Published in Genome Biology (30-01-2017)“…Current three-dimensional (3D) genome modeling platforms are limited by their inability to account for radial placement of loci in the nucleus. We present…”
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Epigenetic Basis for the Differentiation Potential of Mesenchymal and Embryonic Stem Cells
Published in Transfusion medicine and hemotherapy (01-01-2008)“…Stem cells have the ability to self-renew, and give rise to one or more differentiated cell types. Embryonic stem cells can differentiate into all cell types…”
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Stable CpG hypomethylation of adipogenic promoters in freshly isolated, cultured, and differentiated mesenchymal stem cells from adipose tissue
Published in Molecular biology of the cell (01-08-2006)“…Mesenchymal stem cells from adipose tissue can differentiate into mesodermal lineages. Differentiation potential, however, varies between clones of adipose…”
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Promoter DNA methylation patterns of differentiated cells are largely programmed at the progenitor stage
Published in Molecular biology of the cell (15-06-2010)“…Mesenchymal stem cells (MSCs) isolated from various tissues share common phenotypic and functional properties. However, intrinsic molecular evidence supporting…”
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9
Genome-wide analysis of DNA methylation and gene expression patterns in purified, uncultured human liver cells and activated hepatic stellate cells
Published in Oncotarget (29-09-2015)“…Liver fibrogenesis - scarring of the liver that can lead to cirrhosis and liver cancer - is characterized by hepatocyte impairment, capillarization of liver…”
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10
Chromatin environment of histone variant H3.3 revealed by quantitative imaging and genome-scale chromatin and DNA immunoprecipitation
Published in Molecular biology of the cell (01-06-2010)“…In contrast to canonical histones, histone variant H3.3 is incorporated into chromatin in a replication-independent manner. Posttranslational modifications of…”
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Immunoprecipitation of methylated DNA
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2009)“…DNA methylation contributes to the regulation of long-term gene repression by enabling the recruitment of transcriptional repressor complexes to methylated…”
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12
Lineage-specific promoter DNA methylation patterns segregate adult progenitor cell types
Published in Stem cells and development (01-08-2010)“…Mesenchymal stem cells (MSCs) can differentiate into multiple mesodermal cell types in vitro; however, their differentiation capacity is influenced by their…”
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13
Lamin A, Chromatin and FPLD2: Not Just a Peripheral Ménage-à-Trois
Published in Frontiers in cell and developmental biology (09-07-2018)“…At the nuclear periphery, the genome is anchored to A- and B-type nuclear lamins in the form of heterochromatic lamina-associated domains. A-type lamins also…”
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14
How doctors build community and socialize into a clinical department through morning reports. A positioning theory study
Published in PloS one (09-05-2023)“…The morning report is one of the longest surviving hospital practices. Most studies of the morning report focus on the effectiveness of formal medical…”
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Induction of Dedifferentiation, Genomewide Transcriptional Programming, and Epigenetic Reprogramming by Extracts of Carcinoma and Embryonic Stem CellsD
Published in Molecular biology of the cell (01-12-2005)“…Functional reprogramming of a differentiated cell toward pluripotency may have long-term applications in regenerative medicine. We report the induction of…”
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