Search Results - "Sílvia Ligório Fialho"

Anti-Inflammatory Effect of Dexamethasone Controlled Released From Anterior Suprachoroidal Polyurethane Implants on Endotoxin-Induced Uveitis in Rats by Barbosa Saliba, Juliana, Vieira, Lorena, Fernandes-Cunha, Gabriella Maria, Rodrigues Da Silva, Gisele, Ligório Fialho, Sílvia, Silva-Cunha, Armando, Bousquet, Elodie, Naud, Marie-Christine, Ayres, Eliane, Oréfice, Rodrigo Lambert, Tekaya, Meriem, Kowalczuk, Laura, Zhao, Min, Behar-Cohen, Francine

“…Targeted drug delivery to the ocular tissues remains a challenge. Biodegradable intraocular implants allow prolonged controlled release of drugs directly into…”
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Intravitreal lupeol: A new potential therapeutic strategy for noninfectious uveitis by Toledo, Cibele Rodrigues, Paiva, Mayara Rodrigues Brandão, Castro, Brenda Fernanda Moreira, Pereira, Vinicius Viana, Cenachi, Sarah Pereira de Freitas, Vasconcelos-Santos, Daniel Vítor, Fialho, Sílvia Ligório, Silva-Cunha, Armando

“…Lupeol is a pentacyclic triterpene with known anti-inflammatory effects. However, its role in the treatment of noninfectious uveitis has not been explored…”
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Efficacy and Safety Evaluation of Mometasone Furoate in Treating Ocular Inflammation by Lage, Nayara Almeida, de Paiva, Mayara Rodrigues Brandão, Vasconcelos-Santos, Daniel Vitor, Machado, Renes Resende, Fialho, Sílvia Ligório, Silva-Cunha, Armando

“…Mometasone furoate (MF) is a medium-potency synthetic glucocorticosteroid with anti-inflammatory, antipruritic, and vasoconstrictive properties. However, its…”
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UHPLC for quality evaluation of genuine and illegal medicines containing sildenafil citrate and tadalafil by Reis, Naialy Fernandes Araújo, Silva, Luiz Felipe Gomes, Souza, Mateus Araújo Castro e, Fialho, Sílvia Ligório, Souza Moreira, Carolina Paula, Oliveira Andrade, Marcus Vinicius, Paula, Washington Xavier, Gloria, Maria Beatriz Abreu, Pianetti, Gerson Antônio, Fernandes, Christian

“…Abstract One of the highest incidences of illegal drug products is related to phosphodiesterase-5 inhibitors, used in treatment of erectile dysfunction,…”
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Delay of neuropathic pain sensitization after application of dexamethasone-loaded implant in sciatic nerve-injured rats by Bastos, Leandro Francisco Silva, Vago, Juliana Priscila, Caux, Thaís Rolla, Costa, Bruna Lopes, Godin, Adriana Martins, Menezes, Raquel Rezende, Pena, Roberta Ribas, Silva-Cunha, Armando, Sousa, Lirlândia Pires, Machado, Renes Resende, Moraes, Márcio Flávio Dutra, Fialho, Sílvia Ligório, Coelho, Márcio Matos

“…Neuroimmune interactions underlying the development of pain sensitization in models of neuropathic pain have been widely studied. In this study, we evaluated…”
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Molecular genetics and emerging therapies for retinitis pigmentosa: Basic research and clinical perspectives by Dias, Marina França, Joo, Kwangsic, Kemp, Jessica A., Fialho, Silvia Ligório, da Silva Cunha, Armando, Woo, Se Joon, Kwon, Young Jik

“…Retinitis Pigmentosa (RP) is a hereditary retinopathy that affects about 2.5 million people worldwide. It is characterized with progressive loss of rods and…”
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Evaluation of water-in-oil-in-water multiple emulsion and microemulsion as potential adjuvants for immunization with rabies antigen by Leclercq, Sophie Yvette, dos Santos, Roberta Márcia Marques, Macedo, Ludmila Branco, Campos, Patrícia Cota, Ferreira, Tatiane Campos, de Almeida, João Gomes, Seniuk, João Gabriel Toledo, Serakides, Rogéria, Silva-Cunha, Armando, Fialho, Sílvia Ligório

“…Water-in-oil-in-water (W/O/W) multiple emulsions and microemulsions have been studied as potential candidates to be formulated as adjuvants. In this work their…”
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Optimizing Retinal Imaging: Evaluation of ultrasmall TiO2 nanoparticle- fluorescein conjugates for improved Fundus Fluorescein Angiography by França Dias, Marina, Ken Kawassaki, Rodrigo, Amaral de Melo, Lutiana, Araki, Koiti, Raphael Guimarães, Robson, Ligorio Fialho, Sílvia

“…[Display omitted] •Fluorescence angiography has limitations due to rapid clearance of fluorescein.•TiO2 nanoparticles and sodium fluorescein (NPTiO2-FL) were…”
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Implants as drug delivery devices for the treatment of eye diseases by Silva, Gisele Rodrigues da, Fialho, Sílvia Ligório, Siqueira, Rubens Camargo, Jorge, Rodrigo, Cunha Júnior, Armando da Silva

“…The treatment of diseases affecting the posterior segment of the eye is limited by the difficulty in transporting effective doses of drugs to the vitreous,…”
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Ocular pharmacokinetics of acetazolamide from intravitreal implants by high-performance liquid chromatography coupled to tandem mass spectrometry by Reis da Silva, Pedro Henrique, Castro, Matheus Augusto de, Ribeiro, Marcela Coelho Silva, Ferreira, Eduarda Diniz, Gonçalves, José Eduardo, Pianetti, Gérson Antônio, Fialho, Sílvia Ligório, Júnior, Armando da Silva-Cunha, Fernandes, Christian

“…Glaucoma, a leading cause of irreversible blindness, affects about 70 million people globally. Its treatment focuses on reducing intraocular pressure…”
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Vitreous pharmacokinetics and electroretinographic findings after intravitreal injection of acyclovir in rabbits by Damico, Francisco Max, Scolari, Mariana Ramos, Ioshimoto, Gabriela Lourençon, Takahashi, Beatriz Sayuri, da Silva Cunha, Armando, Fialho, Sílvia Ligório, Bonci, Daniela Maria, Gasparin, Fabio, Ventura, Dora Fix

“…Acute retinal necrosis is a rapidly progressive and devastating viral retinitis caused by the herpesvirus family. Systemic acyclovir is the treatment of…”
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Sodium butyrate-loaded nanoparticles coated with chitosan for the treatment of neovascularization in age-related macular degeneration: Ocular biocompatibility and antiangiogenic activity by Reis, Julia Stephania Dos, Dos Reis Teixeira, Aniely, De Vasconcelos Quaresma, Amanda, Almeida, Tamires Cunha, Arribada, Raquel Gregorio, Neto, Julia Teixeira, Da Silva, Fábio Henrique Rodrigues, Silva-Cunha, Armando, Lima De Moura, Sandra Aparecida, Da Silva, Glenda Nicioli, Fialho, Sílvia Ligório, Da Silva, Gisele Rodrigues

“…[Display omitted] Sodium butyrate-loaded nanoparticles coated chitosan (NaBu-loaded nanoparticles/CS) were developed to treat the choroidal neovascularization…”
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Markers to sensibility and relapse on IMR-32 neuroblastoma cell line cultured in monolayer (2D) and neurosphere (3D) models cisplatin-treated by Gonçalves, Bryan Ôrtero Perez, de Andrade, Warne Pedro, Fialho, Sílvia Ligório, Silva, Luciana Maria

“…The complexity of different components of tumor stroma poses huge challenges for therapies targeting the neuroblastoma (NB) microenvironment. The present study…”
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Biodegradable core-shell electrospun nanofibers containing bevacizumab to treat age-related macular degeneration by de Souza, Sarah Oliveira Lamas, Guerra, Maria Carolina Andrade, Heneine, Luiz Guilherme Dias, de Oliveira, Carolina Reis, Cunha Junior, Armando da Silva, Fialho, Sílvia Ligório, Oréfice, Rodrigo Lambert

“…Age-related macular degeneration (AMD) is a degenerative ocular disease that affects the central retina. It is considered the main cause of blindness and loss…”
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Intravitreal thalidomide ameliorates inflammation in a model of experimental uveitis induced by BCG by Castro, Brenda Fernanda Moreira, Vieira, Lorena Carla, Vasconcelos-Santos, Daniel Vitor, Cenachi, Sarah Pereira de Freitas, Cotta, Oliver Araújo Lacerda, Guerra, Maria Carolina Andrade, Paiva, Mayara Rodrigues Brandão, Silva, Luciana Maria, Silva-Cunha, Armando, Fialho, Sílvia Ligório

“…•Intravitreal BCG in sensitized animals induces experimental panuveitis in rabbits.•Treatment with intravitreal thalidomide improves clinical manifestations of…”
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Central nervous system (CNS) tumor cell heterogeneity contributes to differential platinum-based response in an in vitro 2D and 3D cell culture approach by Gonçalves, Bryan Ôrtero Perez, Fialho, Sílvia Ligório, Silvestrini, Bárbara Reis, Sena, Isadora Fernandes Gilson, dos Santos, Gabryella Soares Pinheiro, Assis Gomes, Dawidson, Silva, Luciana Maria

“…One of the models that best explains the cellular heterogeneity observed in central nervous system (CNS) tumors is the presence of cancer stem cells (CSCs)…”
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Intravitreal ketamine promotes neuroprotection in rat eyes after experimental ischemia by Dourado, Lays Fernanda Nunes, Oliveira, Lucas Gomes, da Silva, Carolina Nunes, Toledo, Cibele Rodrigues, Fialho, Silvia Ligório, Jorge, Rodrigo, Silva-Cunha, Armando

“…[Display omitted] •Intravitreal use of ketamine is safe for rat retina.•Ketamine have protective effects on retina injury induced by ischemia model.•The…”
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Clinical outcomes of intravitreal treatment for ocular toxoplasmosis: systematic review and meta-analysis by Melo, Lutiana Amaral de, Paiva, Mayara Rodrigues Brandão de, Fernandes-Cunha, Gabriella Maria, Silva-Cunha, Armando, Mol, Marcos Paulo Gomes, Fialho, Sílvia Ligorio

“…Ocular toxoplasmosis is the leading cause of infectious posterior uveitis worldwide, accounting for 30-50% of all cases in immunocompetent patients…”
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Dexamethasone-loaded poly(ε-caprolactone) intravitreal implants: A pilot study by Fialho, Silvia Ligório, Behar-Cohen, Francine, Silva-Cunha, Armando

“…Purpose: Poly(ε-caprolactone) (PCL) is a biodegradable and biocompatible polymer that presents a very low degradation rate, making it suitable for the…”
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New vehicle based on a microemulsion for topical ocular administration of dexamethasone by Fialho, Sílvia Ligório, Da Silva-Cunha, Armando

“…Aim: Eye drops are the most used dosage form by the ocular route, in spite of their low bioavailability. Due to their properties and numerous advantages,…”
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