Search Results - "Sárosi, Menyhárt‐Botond"

Reactivity of Perhalogenated Octahedral Phospha- and Arsaboranes toward THF: A Joint Experimental/Computational Study by Keller, Willi, Hofmann, Matthias, Sárosi, Menyhárt-Botond, Fanfrlík, Jindřich, Hnyk, Drahomír

“…Reactions of the perhalogenated polyhedral pnictogenaboranes closo-1,2-Pn2B4Hal4 (Pn = P, As; Hal = Cl, Br) with Lewis bases are presently being studied with a…”
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Molecular Dynamics Simulation of Cyclooxygenase‑2 Complexes with Indomethacin closo-Carborane Analogs by Sárosi, Menyhárt-Botond, Lybrand, Terry P

“…Molecular dynamics simulation of carborane-containing ligands in complex with target enzymes is a challenging task due to the unique structure and properties…”
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Binding of indomethacin methyl ester to cyclooxygenase-2. A computational study by Sárosi, Menyhárt-Botond

“…Inhibitors selective towards the second isoform of prostaglandin synthase (cyclooxygenase, COX-2) are promising nonsteroidal anti-inflammatory drugs and…”
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Molecular Modeling of the Interactions between Carborane-Containing Analogs of Indomethacin and Cyclooxygenase‑2 by Sárosi, Menyhárt-Botond, Neumann, Wilma, Lybrand, Terry P, Hey-Hawkins, Evamarie

“…Molecular modeling studies were performed in order to gain insight into the binding mode and interaction of carborane-containing derivatives of indomethacin…”
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Carboranyl Analogues of Celecoxib with Potent Cytostatic Activity against Human Melanoma and Colon Cancer Cell Lines by Buzharevski, Antonio, Paskas, Svetlana, Sárosi, Menyhárt‐Botond, Laube, Markus, Lönnecke, Peter, Neumann, Wilma, Mijatovic, Sanja, Maksimovic‐Ivanic, Danijela, Pietzsch, Jens, Hey‐Hawkins, Evamarie

“…Nonsteroidal anti‐inflammatory drugs (NSAIDs) are the most common way of treating inflammatory disorders. Their widespread use helped reveal their other modes…”
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Carboranyl Derivatives of Rofecoxib with Cytostatic Activity against Human Melanoma and Colon Cancer Cells by Buzharevski, Antonio, Paskaš, Svetlana, Sárosi, Menyhárt-Botond, Laube, Markus, Lönnecke, Peter, Neumann, Wilma, Murganić, Blagoje, Mijatović, Sanja, Maksimović-Ivanić, Danijelа, Pietzsch, Jens, Hey-Hawkins, Evamarie

“…Owing to the involvement of cyclooxygenase-2 (COX-2) in carcinogenesis, COX-2-selective inhibitors are increasingly studied for their potential cytotoxic…”
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Carborane‐Based Analogues of 5‐Lipoxygenase Inhibitors Co‐inhibit Heat Shock Protein 90 in HCT116 Cells by Kuhnert, Robert, Sárosi, Menyhárt‐Botond, George, Sven, Lönnecke, Peter, Hofmann, Bettina, Steinhilber, Dieter, Steinmann, Sara, Schneider‐Stock, Regine, Murganić, Blagoje, Mijatović, Sanja, Maksimović‐Ivanić, Danijela, Hey‐Hawkins, Evamarie

“…5‐Lipoxygenase converts arachidonic acid into leukotrienes, which are involved in inflammation and angiogenesis. The introduction of carboranes can improve the…”
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CarbORev‐5901: The First Carborane‐Based Inhibitor of the 5‐Lipoxygenase Pathway by Kuhnert, Robert, Sárosi, Menyhárt‐Botond, George, Sven, Lönnecke, Peter, Hofmann, Bettina, Steinhilber, Dieter, Murganic, Blagoje, Mijatovic, Sanja, Maksimovic‐Ivanic, Danijela, Hey‐Hawkins, Evamarie

“…The progression of cancer is accelerated by increased proliferation, angiogenesis, and inflammation. These processes are mediated by leukotrienes. Several…”
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Tannins and Tannin-Related Derivatives Enhance the (Pseudo-)Halogenating Activity of Lactoperoxidase by Gau, Jana, Prévost, Martine, Van Antwerpen, Pierre, Sarosi, Menyhárt-Botond, Rodewald, Steffen, Arnhold, Jürgen, Flemmig, Jörg

“…Several hydrolyzable tannins, pro­antho­cyanidins, tannin derivatives, and a tannin-rich plant extract of tormentil rhizome were tested for their potential to…”
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Cover Feature: Carboranyl Analogues of Celecoxib with Potent Cytostatic Activity against Human Melanoma and Colon Cancer Cell Lines (ChemMedChem 3/2019) by Buzharevski, Antonio, Paskas, Svetlana, Sárosi, Menyhárt‐Botond, Laube, Markus, Lönnecke, Peter, Neumann, Wilma, Mijatovic, Sanja, Maksimovic‐Ivanic, Danijela, Pietzsch, Jens, Hey‐Hawkins, Evamarie

“…The Cover Feature shows carboranyl analogues of celecoxib, a potent COX‐2‐selective inhibitor (COXIB). Cyclooxygenase‐2 (COX‐2) has a prominent role in the…”
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