Search Results - "Sánchez de la Cuesta, F"
-
1
Gender differences in the effect of aspirin on retinal ischemia, prostanoid synthesis and nitric oxide production in experimental type 1-like diabetes
Published in Vascular pharmacology (01-08-2007)“…Abstract Background The protective effect of acetylsalicylic acid (aspirin) against cardiovascular events is known to be weaker in women than in men. The…”
Get full text
Journal Article -
2
Effect of propofol on oxidative stress in an in vitro model of anoxia-reoxygenation in the rat brain
Published in Brain research (27-07-1998)“…Propofol, an intravenous anaesthetic, is similar in chemical structure to the active nucleus of antioxidant substances such as α-tocopherol (vitamin E). The…”
Get full text
Journal Article -
3
Clonidine decreases intraoperative bleeding in middle ear microsurgery
Published in Acta anaesthesiologica Scandinavica (01-05-2001)“…Background: The antihypertensive drug clonidine is a centrally acting α2 agonist useful as a premedicant because of its sedative, anxiolytic, and analgesic…”
Get full text
Journal Article -
4
Effects of clopidogrel and ticlopidine on experimental diabetic ischemic retinopathy in rats
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-02-2003)“…Ticlopidine, a thienopyridine that prevents the progression of diabetic retinopathy in humans, was recently shown to increase nitric oxide (NO) production in…”
Get full text
Journal Article -
5
Influence of triflusal on platelet activation after coronary artery bypass graft
Published in Blood coagulation & fibrinolysis (01-03-2000)“…The aim of the study was to investigate the effects of the antiplatelet agent triflusal on the changes in platelet function in patients who underwent a…”
Get more information
Journal Article -
6
Effects of the selective inhibition of platelet thromboxane synthesis on the platelet‐subendothelium interaction
Published in British journal of pharmacology (01-12-2002)“…Drugs that inhibit TxA2 synthesis are used to reduce platelet aggregation. The aim of this study was to compare the effects of a cyclo‐oxygenase (COX)…”
Get full text
Journal Article -
7
Effect of aspirin on prostanoids and nitric oxide production in streptozotocin-diabetic rats with ischemic retinopathy
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-02-2002)“…The importance in experimental diabetic retinopathy of prostacyclin and nitric oxide (NO), as well as the possible effect of acetylsalicylic acid (ASA), are…”
Get full text
Journal Article -
8
Effects of aspirin plus alpha-tocopherol on brain slices damage after hypoxia-reoxygenation in rats with type 1-like diabetes mellitus
Published in Neuroscience letters (12-06-2006)“…Diabetes mellitus is a risk factor for cerebrovascular ischemic disease. Aspirin (acetylsalicylic acid) is the most widely used drug for the secondary…”
Get full text
Journal Article -
9
Effects of hypoxia reoxygenation in brain slices from rats with type 1-like diabetes mellitus
Published in Diabetes/metabolism research and reviews (01-09-2006)“…Background The aim of this study was to determine whether the brain tissue of type 1 diabetic animals is more susceptible to damage by hypoxia reoxygenation…”
Get full text
Journal Article -
10
Effects of two preparations of 75-mg extended-release aspirin on platelet aggregation, prostanoids and nitric oxide production in humans
Published in European journal of clinical pharmacology (2002)“…The lowest dose of aspirin shown to be effective in the secondary prevention of thrombotic accidents is 75 mg/day. Presystemic acetylation of cyclooxygenase…”
Get full text
Journal Article -
11
Antioxidant effect of acetylsalicylic and salicylic acid in rat brain slices subjected to hypoxia
Published in Journal of neuroscience research (15-01-2004)“…Acetylsalicylic acid (ASA) reduces the incidence of ischemic stroke mainly through its antithrombotic action; however, it also has a direct neuroprotective…”
Get full text
Journal Article -
12
Lipid peroxidation and glutathione system in hyperlipemic rabbits: influence of olive oil administration
Published in Biochimica et biophysica acta (06-05-2000)“…We studied the effect of supplementation (10% w/w) of a hyperlipemic diet (1% cholesterol) with olive oil (OLIV) for 6 weeks in four groups of 10 rabbits each…”
Get full text
Journal Article -
13
Antioxidant effects of a single dose of acetylsalicylic acid and salicylic acid in rat brain slices subjected to oxygen-glucose deprivation in relation with its antiplatelet effect
Published in Neuroscience letters (01-04-2004)“…The aim of the present study was to analyze the relative participation of the antiplatelet and the antioxidant effects of acetylsalicylic acid (ASA) and…”
Get full text
Journal Article -
14
Antioxidant and antiplatelet effects of the alpha-tocopherol–aspirin combination in type 1-like diabetic rats
Published in Life sciences (1973) (05-09-2006)“…We analyze the effect of the combination of acetylsalicylic acid (2 mg/kg/day p.o.) and alpha-tocopherol (25 mg/kg/day p.o.) in a type-1-like experimental…”
Get full text
Journal Article -
15
The Effect of Propofol on the Interaction of Platelets with Leukocytes and Erythrocytes in Surgical Patients
Published in Anesthesia and analgesia (01-03-2003)“…We tested the antiplatelet effect described for propofol in vitro in surgical patients. Platelet aggregation induced by adenosine diphosphate, collagen, and…”
Get full text
Journal Article -
16
Otenzepad shows two populations of binding sites in human gastric smooth muscle
Published in Canadian journal of physiology and pharmacology (01-01-1995)“…Cholinergic agonists and antagonists frequently used for gastrointestinal motility disorders often produce adverse effects. A possible explanation for this is…”
Get more information
Journal Article -
17
Effects of triflusal on oxidative stress, prostaglandin production and nitric oxide pathway in a model of anoxia-reoxygenation in rat brain slices
Published in Brain research (18-06-2004)“…Acetylsalicylic acid (ASA) is the most widely used drug in the prevention of ischemic vascular accidents, mainly because of its antithrombotic effect…”
Get full text
Journal Article -
18
Influence of vitamin E on the antiplatelet effect of acetylsalicylic acid in human blood
Published in Platelets (Edinburgh) (01-05-2005)“…We analysed the in vitro interaction between acetylsalicylic acid and vitamin E on the principal antiplatelet sites of action of acetylsalicylic acid, i.e.,…”
Get full text
Journal Article -
19
Effect of S-adenosyl- l-methionine on rat brain oxidative stress damage in a combined model of permanent focal ischemia and global ischemia-reperfusion
Published in Brain research (10-11-2000)“…We analyzed the effects of S-adenosyl- l-methionine (SAM) on tissue oxidative status in a combined model of permanent focal ischemia and global reperfusion in…”
Get full text
Journal Article -
20
The in vitro effects of propofol on tissular oxidative stress in the rat
Published in Anesthesia and analgesia (01-11-1998)“…This study was designed to evaluate the in vitro effects of propofol on lipid peroxide formation and the glutathione antioxidant system in some tissues of…”
Get full text
Journal Article