Search Results - "Sánchez Zapardiel, Elena"

The challenge of standardizing CAR‐T cell monitoring: A comparison of two flow‐cytometry methods and correlation with qPCR technique by Valdivieso‐Shephard, Juan Luis, Matas‐Pérez, Elisabet, García‐Bujalance, Silvia, Mirones‐Aguilar, Isabel, González‐Martínez, Berta, Pérez‐Martínez, Antonio, López‐Granados, Eduardo, Martínez‐Feito, Ana, Sánchez‐Zapardiel, Elena

“…Chimeric antigen receptor (CAR) T‐cell therapy is a breakthrough in hematologic malignancies, such as acute B lymphoblastic leukemia (B‐ALL). Monitoring this…”
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Epstein-Barr virus-specific T-cell response in pediatric liver transplant recipients: a cross-sectional study by multiparametric flow cytometry by Cuesta-Martín de la Cámara, Ricardo, Torices-Pajares, Andrea, Miguel-Berenguel, Laura, Reche-Yebra, Keren, Frauca-Remacha, Esteban, Hierro-Llanillo, Loreto, Muñoz-Bartolo, Gema, Lledín-Barbacho, María Dolores, Gutiérrez-Arroyo, Almudena, Martínez-Feito, Ana, López-Granados, Eduardo, Sánchez-Zapardiel, Elena

“…Epstein-Barr virus (EBV) specific T-cell response measurement can help adjust immunosuppression in transplant patients with persistent infections. We aim to…”
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Humoral and cellular immune responses to Pfizer-BioNTech BNT162b2 SARS-CoV-2 vaccine in adolescents with liver transplantation: Single center experience by Sánchez-Zapardiel, Elena, Alós, María, Nozal, Pilar, González-Muñoz, Miguel, Frauca-Remacha, Esteban, Gavilán, Lucía Blanca, Quiles, María José, Hierro, Loreto, López-Granados, Eduardo

“…Immune responses to vaccines against severe acute respiratory syndrome (SARS)-coronavirus (CoV)-2 are variable. In the absence of disease, youngsters are…”
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CD19+ lineage chimerism, an early biomarker after anti-CD19 CAR-T cell therapy in patients previously receiving a hematopoietic stem cell transplantation by Martínez-Romera, Isabel, Galán-Gómez, Víctor, González-Martínez, Berta, Guerra García, Pilar, San Román Pacheco, Sonsoles, Corral Sánchez, Dolores, Mozo del Castillo, Yasmina, Bueno Sánchez, David, Sisinni, Luisa, González Guerrero, Alba, Castellano Dámaso, Serafin, Sánchez Zapardiel, Elena, Ruz Caracuel, Beatriz, Balas Pérez, Antonio, Pérez-Martínez, Antonio

“…Treatment targeting CD19 by a chimeric antigen receptor expressed on T cells (anti-CD19 CAR-T) has led to a breakthrough in the management and treatment of…”
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Isolated De Novo Antiendothelial Cell Antibodies and Kidney Transplant Rejection by Sánchez-Zapardiel, Elena, MSc, Mancebo, Esther, PhD, Díaz-Ordoñez, María, BSc, de Jorge-Huerta, Lucía, BSc, Ruiz-Martínez, Lara, BSc, Serrano, Antonio, MD, PhD, Castro-Panete, María J., PhD, Utrero-Rico, Alberto, BSc, de Andrés, Amado, MD, PhD, Morales, José M., MD, PhD, Domínguez-Rodríguez, Sara, BSc, Paz-Artal, Estela, MD, PhD

“…Background Studies analyzing the role of antiendothelial cell antibodies (AECAs) in large series of kidney transplant recipients are scarce, and HLA, MHC…”
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Familial CD45RA - T cells to treat severe refractory infections in immunocompromised patients by Al-Akioui Sanz, Karima, Echecopar Parente, Carlos, Ferreras, Cristina, Menéndez Ribes, Marta, Navarro, Alfonso, Mestre, Carmen, Clares, Laura, Vicario, José Luis, Balas, Antonio, De Paz, Raquel, López Granados, Eduardo, Sánchez Zapardiel, Elena, Jiménez, Carlos, López-Oliva, María, Ramos, Esther, Hernández-Oliveros, Francisco, Pérez-Martínez, Antonio

“…Immunocompromised patients are susceptible to high-risk opportunistic infections and malignant diseases. Most antiviral and antifungal drugs are quite toxic,…”
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Complement C3F allotype synthesized by liver recipient modifies transplantation outcome independently from donor hepatic C3 by Valero‐Hervás, Diana María, Sánchez‐Zapardiel, Elena, Castro, María José, Gallego‐Bustos, Fernando, Cambra, Félix, Justo, Iago, Laguna‐Goya, Rocío, Jiménez‐Romero, Carlos, Moreno, Enrique, López‐Medrano, Francisco, San Juan, Rafael, Fernández‐Ruiz, Mario, Aguado, José María, Paz‐Artal, Estela

“…Complement component 3 (C3) presents both slow (C3S) and fast (C3F) variants, which can be locally produced and activated by immune system cells. We studied C3…”
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Suppression of anoikis by collagen coating of interconnected macroporous nanometric carbonated hydroxyapatite/agarose scaffolds by Alcaide, María, Serrano, María-Concepción, Roman, Jesús, Cabañas, María-Victoria, Peña, Juan, Sánchez-Zapardiel, Elena, Vallet-Regí, María, Portolés, María-Teresa

“…Three dimensional interconnected macroporous (pore diameter: 600–800 μm) hydroxyapatite/agarose disks have been evaluated in this study as potential bone…”
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Severe Impairment of T-cell Immunity and Pulmonary GvHD Are Major Risk Factors for Nontuberculous Mycobacterial Infection After Pediatric Allogeneic Hematopoietic Stem Cell Transplantation by Ascunce, Marina, Coccolo, Alejandra, Mozo, Yasmina, Baquero-Artigao, Fernando, Rodriguez-Molino, Paula, Toro-Rueda, Carlos, García-Clemente, Paloma, Sánchez-Zapardiel, Elena, López-Granados, Eduardo, Corral-Sánchez, Dolores, Bueno, David, Sisinni, Luisa, Pérez-Martínez, Antonio, Calvo, Cristina, Del Rosal, Teresa

“…Hematopoietic stem cell transplant recipients are prone to infectious complications. Infections caused by nontuberculous mycobacteria have increased in adults…”
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Failure of Viral-Specific T Cells Administered in Pre-transplant Settings in Children with Inborn Errors of Immunity by Alonso, Laura, Méndez-Echevarría, Ana, Rudilla, Francesc, Mozo, Yasmina, Soler-Palacin, Pere, Sisinni, Luisa, Bueno, David, Riviere, Jacques, de Paz, Raquel, Sánchez-Zapardiel, Elena, Querol, Sergi, Rodriguez-Pena, Rebeca, López-Granados, Eduardo, Gimeno, Ramón, Díaz de Heredia, Cristina, Pérez-Martínez, Antonio

“…Purpose Use of adoptive immunotherapy with virus-specific T cells (VST) in patients with inborn errors of immunity prior to hematopoietic stem cell…”
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Early renal graft function deterioration in recipients with preformed anti-MICA antibodies: partial contribution of complement-dependent cytotoxicity by Sánchez-Zapardiel, Elena, Castro-Panete, María José, Mancebo, Esther, Morales, Pablo, Laguna-Goya, Rocío, Morales, José María, Apaza, Jacqueline, de Andrés, Amado, Talayero, Paloma, Paz-Artal, Estela

“…We previously reported that preformed anti-MHC class I-related chain A (MICA) antibodies increase the risk for renal graft rejection and enhance the…”
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Autoimmune lymphoproliferative syndrome due to somatic FAS mutation (ALPS-sFAS) combined with a germline caspase-10 ( CASP10 ) variation by Martínez-Feito, Ana, Melero, Josefa, Mora-Díaz, Sergio, Rodríguez-Vigil, Carmen, Elduayen, Ramón, González-Granado, Luis I, Pérez-Méndez, Dolores, Sánchez-Zapardiel, Elena, Ruiz-García, Raquel, Menchén, Miguela, Díaz-Madroñero, Josefa, Paz-Artal, Estela, del Orbe-Barreto, Rafael, Riñón, Marta, Allende, Luis M

“…Abstract Autoimmune lymphoproliferative syndrome (ALPS) is a primary immunodeficiency caused by impaired Fas/FasL-mediated apoptosis of lymphocytes and is…”
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A case‐control study to assess the role of polyomavirus in transplant complications: Where do we stand? by Garcia Urbán, Julia, Gurrado, Katia, Brea Rivas, Paola C., Abou Elrous, Dina, Zubimendi Machain, Mónica, Romero Gómez, María, García Rodríguez, Julio, Vicandi Plaza, Blanca, Yébenes Gregorio, Laura, García Fernández, Eugenia, Jiménez Martín, Carlos, López Oliva, María‐Ovidia, González García, Elena, Ledesma Sánchez, Gabriel, Carreño Cornejo, Gilda, Selgas Gutiérrez, Rafael, Zarauza Santoveña, Alejandro, Melgosa Hijosa, Marta, Fernández Camblor, Carlota, Mozo del Castillo, Yasmina, Sisinni, Luisa, Bueno Sánchez, David, Pérez‐Martínez, Antonio, Sánchez Zapardiel, Elena, López Granados, Eduardo, Monserrat Villatoro, Jaime, Hernández Zabala, Rafael, Borobia, Alberto M., Frías, Jesús, Ramírez, Elena

“…Purpose The study's aim was to assess whether polyomavirus DNAemia screening was associated with different outcomes in patients with positive viremia compared…”
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Harmful Effect of Preformed Anti-MICA Antibodies on Renal Allograft Evolution in Early Posttransplantation Period by Sánchez-Zapardiel, Elena, Castro-Panete, María J, Castillo-Rama, Marcela, Morales, Pablo, Lora-Pablos, David, Valero-Hervás, Diana, Ruiz-García, Raquel, Apaza, Jacqueline, Talayero, Paloma, Andrés, Amado, Morales, José M, Paz-Artal, Estela

“…BACKGROUNDPretransplantation anti–major histocompatibility complex class I chain–related molecule A (MICA) sensitization is an uncommon event and its role on…”
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Blockade of cell adhesion molecules enhances cell engraftment in a murine model of liver cell transplantation by Alfaro, Javier, Pérez, Dolores, Jiménez, Carlos, Serrano, Manuel, Martínez-Flores, José Ángel, Grau, Montserrat, Sánchez-Zapardiel, Elena, Paz-Artal, Estela, Serrano, Antonio

“…Abstract Aim OLT is the best alternative for patients with end-stage liver diseases. However, as the need for organs surpasses donor availability, alternatives…”
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Mes de nacimiento, HLA-DRB1 y riesgo de esclerosis múltiple en la descendencia by Guijarro-Castro, Cristina, Sánchez Zapardiel, Elena, Muñoz García, Delicias, Fernández Fernández, Óscar, Leyva Fernández, Laura, Castro Panete, María José, Picón Muñoz, Carmen, Talise, Marta, Martínez Feito, Ana, Paz Artal, Estela

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Breaking Barriers in B-Acute Lymphoblastic Leukemia Treatment: Experience of a Tertiary Hospital with the Use of a Tandem Dual CAR-T 19/22 in Pediatric & AYA Patients by González-Martínez, Berta, Galán-Gómez, Víctor, Minguillon Pedreno, Jordi, Navarro-Zapata, Alfonso, Mirones-Aguilar, Isabel, Sánchez-Zapardiel, Elena, Echecopar, Carlos, Martínez-Romera, Isabel, Pérez-Martínez, Antonio

“…INTRODUCTION Anti-CD19 chimeric antigen receptor (CAR) autologous T-cell therapy tisagenlecleucel (CTL019) has shown efficacy in pivotal trials and real-world…”
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245.3: Sirolimus treatment increases graft survival in pediatric intestinal transplant patients and is associated with a more naïve/less activated immune phenotype, and a higher frequency of regulatry T-cells by Papa-Gobbi, Rodrigo, Andrés-Moreno, Ane, Sánchez-Zapardiel, Elena, Alcolea-Sánchez, Alida, González-Sacristán, Rocío, Peña Saínz-Pardo, Eva, Serradilla-Rodríguez, Javier, Sánchez-Galán, Alba, Ramos Boluda, Esther, Hernández-Oliveros, Fransico

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Results of phase 2 randomized multi-center study to evaluate the safety and efficacy of infusion of memory T cells as adoptive therapy in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia and/or lymphopenia (RELEASE NCT04578210) by Ferreras, Cristina, Hernández-Blanco, Clara, Martín-Quirós, Alejandro, Al-Akioui-Sanz, Karima, Mora-Rillo, Marta, Ibáñez, Fátima, Díaz-Almirón, Mariana, Cano-Ochando, Jordi, Lozano-Ojalvo, Daniel, Jiménez-González, María, Goterris, Rosa, Sánchez-Zapardiel, Elena, de Paz, Raquel, Guerra-García, Pilar, Queiruga-Parada, Javier, Molina, Pablo, Briones, María Luisa, Ruz-Caracuel, Beatriz, Borobia, Alberto M, Carcas, Antonio J, Planelles, Dolores, Vicario, José Luis, Moreno, Miguel Ángel, Balas, Antonio, Llano, Marta, Llorente, Andrea, Del Balzo, Álvaro, Cañada, Carlos, García, Miguel Ángel, Calvin, María Elena, Arenas, Isabel, Pérez de Diego, Rebeca, Eguizábal, Cristina, Soria, Bernat, Solano, Carlos, Pérez-Martínez, Antonio

“…There are currently no effective anti-viral treatments for coronavirus disease 2019 (COVID-19)-hospitalized patients with hypoxemia. Lymphopenia is a biomarker…”
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Month of birth, HLA-DRB115 locus and risk of multiple sclerosis in offspring by Guijarro-Castro, C, Sanchez-Zapardiel, E, Munoz, D, Fernandez, O, Leyva, L, Castro-Panete, M J, Picon-Munoz, C, Talise, M, Martinez-Feito, A, Paz-Artal, E

“…A relationship among April births, HLA-DRB1*15:01 genotype and risk of multiple sclerosis (MS) has been described. We aim to determine this association in our…”
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