Search Results - "Sánchez García, R."

In silico design and cell-based evaluation of two dual anti breast cancer compounds targeting Bcl-2 and GPER by Morelos-Garnica, Loreley-A., Guzmán-Velázquez, Sonia, Padilla-Martínez, Itzia-I., García-Sánchez, José-R., Bello, Martiniano, Bakalara, Norbert, Méndez-Luna, David, Correa-Basurto, José

“…According to WHO statistics, breast cancer (BC) disease represents about 2.3 million diagnosed and 685,000 deaths globally. Regarding histological…”
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Integration of Cryo-EM Model Building Software in Scipion by Martínez, M, Jiménez-Moreno, A, Maluenda, D, Ramírez-Aportela, E, Melero, R, Cuervo, A, Conesa, P, del Caño, L, Fonseca, Y. C, Sánchez-García, R, Strelak, D, Conesa, J. J, Fernández-Giménez, E, de Isidro, F, Sorzano, C. O. S, Carazo, J. M, Marabini, R

“…Advances in cryo-electron microscopy (cryo-EM) have made it possible to obtain structures of large biological macromolecules at near-atomic resolution. This…”
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On bias, variance, overfitting, gold standard and consensus in single‐particle analysis by cryo‐electron microscopy by Sorzano, C. O. S., Jiménez-Moreno, A., Maluenda, D., Martínez, M., Ramírez-Aportela, E., Krieger, J., Melero, R., Cuervo, A., Conesa, J., Filipovic, J., Conesa, P., del Caño, L., Fonseca, Y. C., Jiménez-de la Morena, J., Losana, P., Sánchez-García, R., Strelak, D., Fernández-Giménez, E., de Isidro-Gómez, F. P., Herreros, D., Vilas, J. L., Marabini, R., Carazo, J. M.

“…Cryo‐electron microscopy (cryoEM) has become a well established technique to elucidate the 3D structures of biological macromolecules. Projection images from…”
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Zoo guide to network embedding by Baptista, A, Sánchez-García, R J, Baudot, A, Bianconi, G

“…Abstract Networks have provided extremely successful models of data and complex systems. Yet, as combinatorial objects, networks do not have in general…”
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Algorithmic robustness to preferred orientations in single particle analysis by CryoEM by Sorzano, C.O.S., Semchonok, D., Lin, S.-C., Lo, Y.-C., Vilas, J.L., Jiménez-Moreno, A., Gragera, M., Vacca, S., Maluenda, D., Martínez, M., Ramírez-Aportela, E., Melero, R., Cuervo, A., Conesa, J.J., Conesa, P., Losana, P., Caño, L. del, de la Morena, J. Jiménez, Fonseca, Y.C., Sánchez-García, R., Strelak, D., Fernández-Giménez, E., de Isidro, F., Herreros, D., Kastritis, P.L., Marabini, R., Bruce, B.D., Carazo, J.M.

“…[Display omitted] The presence of preferred orientations in single particle analysis (SPA) by cryo-Electron Microscopy (cryoEM) is currently one of the hurdles…”
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Survey of the analysis of continuous conformational variability of biological macromolecules by electron microscopy by Sorzano, C. O. S., Jiménez, A., Mota, J., Vilas, J. L., Maluenda, D., Martínez, M., Ramírez-Aportela, E., Majtner, T., Segura, J., Sánchez-García, R., Rancel, Y., del Caño, L., Conesa, P., Melero, R., Jonic, S., Vargas, J., Cazals, F., Freyberg, Z., Krieger, J., Bahar, I., Marabini, R., Carazo, J. M.

“…Single‐particle analysis by electron microscopy is a well established technique for analyzing the three‐dimensional structures of biological macromolecules…”
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Flexible workflows for on‐the‐fly electron‐microscopy single‐particle image processing using Scipion by Maluenda, D., Majtner, T., Horvath, P., Vilas, J. L., Jiménez-Moreno, A., Mota, J., Ramírez-Aportela, E., Sánchez-García, R., Conesa, P., del Caño, L., Rancel, Y., Fonseca, Y., Martínez, M., Sharov, G., García, C.A., Strelak, D., Melero, R., Marabini, R., Carazo, J. M., Sorzano, C. O. S.

“…Electron microscopy of macromolecular structures is an approach that is in increasing demand in the field of structural biology. The automation of image…”
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Impact of the ENDORSE study results on thromboprophylaxis prescribing patterns in medical patients attending the emergency department by de Lorenzo-Pinto, A, García-Sánchez, R, Pascual Izquierdo, C, Durán-García, M E, Castuera-Gil, A I, Andueza-Lillo, J A, Sanjurjo-Sáez, M

“…The aim of the study was to evaluate the impact of the ENDORSE study results on thromboprophylaxis prescribing patterns in medical patients attending the…”
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Modeling type 2 diabetes in rats by administering tacrolimus by Quintana-Pérez, JC, García-Dolores, F, Valdez-Guerrero, AS, Alemán-González-Duhart, D, Arellano-Mendoza, MG, Rojas Hernández, S, Olivares-Corichi, IM, García Sánchez, JR, Trujillo Ferrara, JG, Tamay-Cach, F

“…The prevalence of diabetes is rapidly increasing. The current number of diagnosed cases is ~422 million, expected to reach ~640 million by 2040. Type 2…”
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Newly diagnosed adult AML and MPAL patients frequently show clonal residual hematopoiesis by Fernandez, C, Santos-Silva, M C, López, A, Matarraz, S, Jara-Acevedo, M, Ciudad, J, Gutierrez, M L, Sánchez, M L, Salvador-Osuna, C, Berruezo, M J, Díaz-Arias, J Á, Palomo-Hernández, A M, Colado, E, González, N, Gallardo, D, Asensio, A, García-Sánchez, R, Saldaña, R, Cerveró, C, Carboné-Bañeres, A, Gutierrez, O, Orfao, A

“…Adult acute myeloid leukemia (AML) is a highly heterogeneous stem cell malignancy characterized by the clonal expansion of immature myeloid precursors. AML may…”
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Multisensory Perception and Action in 3-Ball Cascade Juggling by Sánchez García, R., Hayes, S. J., Williams, A. M., Bennett, S. J.

“…Multisensory perception and action in 3-ball cascade juggling was investigated in intermediate-skilled performers by manipulating vision (full or lower field…”
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Suffering indicators in terminally ill children from the parental perspective by Montoya-Juárez, R, García-Caro, M.P, Schmidt-Rio-Valle, J, Campos-Calderón, C, Sorroche-Navarro, C, Sánchez-García, R, Cruz-Quintana, F

“…Abstract Purpose Suffering is a complex multifaceted phenomenon, which has received limited attention in relation to children with terminal illness. As part of…”
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Identification of Spanish Trichinella isolates by ISSR-PCR: Intra-specific variability of Trichinella britovi by Perteguer, M.J., Rodríguez, E., García-Sánchez, R.N., Nogal-Ruiz, J.J., Bolas-Fernández, F., Martínez-Fernández, A.R., Gárate, T.

“…In the present work, we investigated genetic variability of the Spanish Trichinella isolates by ISSR-PCR (inter-simple sequence repeat polymerase chain…”
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Prevalence of Trichinella spp. in North Spain wild fauna and new variety of Trichinella britovi identification by Fonseca-Salamanca, F., Nogal-Ruiz, J.J., García-Sánchez, R.N., Bolas-Fernandez, F., Jiménez, S., Álamo, R., Gárate, T., Martínez-Fernandez, A.R.

“…Trichinella spiralis and Trichinella britovi live in apparent sympatry among wild fauna of the Iberian Peninsula. In the present study 105 Trichinella isolates…”
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5PSQ-148 TANDEM project: transitions of care and medication reconciliation in high-risk patients by Ortega Navarro, C, de Lorenzo Pinto, A, García Sánchez, R, Torroba Sanz, B, Herranz Alonso, A, Sanjurjo Sáez, M

“…Background and importanceThe implementation of medication reconciliation programmes is a quality standard in health centres according to the recommendations of…”
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It is possible to mix insulins in the same syringe? by González Sevilla, M, de Lorenzo Pinto, A, García Sánchez, R, Ortega Navarro, C

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Insulin polymers in the plasma of obese subjects are associated with elevated levels of carbonyl groups and are decreased by (-)-epicatechin by Rincón Víquez, M J, García-Sánchez, J R, Tapia González, M A, Gutiérrez López, L, Ceballos-Reyes, G M, Olivares-Corichi, I M

“…We investigated whether oxidative damage and insulin polymerization at a systemic level are associated with the insulin resistance (IR) observed in obese…”
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4CPS-228 Vernakalant versus flecainide for conversion of recent onset atrial fibrillation in patients attending the emergency department by Somoza, B, De Lorenzo Pinto, A, Ortega Navarro, C, García Sánchez, R, Castuera Gil, A, Miguens Blanco, I, Herranz Alonso, A, Sanjurjo Saez, M

“…Background and importanceFlecainide is commonly used for conversion of recent onset (<48 hours) atrial fibrillation (AF) in haemodynamically stable patients…”
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4CPS-051 Antibiotics in the emergency department: is it possible to improve prescriptions for infectious respiratory diseases in ambulatory patients? by Ruiz Briones, P, García Sánchez, R, Ortega Navarro, C, García, MÁ Amor, García Moreno, F, Melgarejo Ortuño, A, García Sánchez, S, Moraza, Á Narrillos, Herranz Alonso, A, Sanjurjo Saez, M

“…Background and importanceDue to the rising rate of antibiotic resistance over the past years, healthcare authorities have developed different strategies to…”
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Hospitalizations due to severe hypoglycemia in patients with diabetes mellitus in Spain by Lindner, L, García-Sánchez, R, Alvarez, C, Betegón, L, Badia, X

“…BACKGROUND AND OBJECTIVESOne of the most important therapeutic complications in patients with diabetes mellitus (DM) is hypoglycemia. This study has estimated…”
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