Search Results - "Sánchez‐Torres, José Miguel"
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Emotional Distress in Cancer Patients During the First Wave of the COVID-19 Pandemic
Published in Frontiers in psychology (05-11-2021)“…The COVID-19 pandemic has caused mental health problems worldwide. The psychopathological implications of COVID-19 in cancer patients have rarely been…”
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Peripheral Blood Mononuclear Cells Predict Therapeutic Efficacy of Immunotherapy in NSCLC
Published in Cancers (12-06-2022)“…In lung cancer immunotherapy, biomarkers to guide clinical decisions are limited. We now explore whether the detailed immunophenotyping of circulating…”
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Clinical management and outcome of patients with advanced NSCLC carrying EGFR mutations in Spain
Published in BMC cancer (30-01-2018)“…Although the benefit of first-line epidermal growth factor receptor (EGFR) tyrosine-kinase inhibitors (TKIs) over chemotherapy has been demonstrated in several…”
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Brief report: High incidence of peridiagnosis thromboembolic events in patients with BRAF-mutant lung cancer
Published in Thrombosis research (01-12-2023)“…INTRODUCTIONWe aimed to determine if advanced BRAF-mutant NSCLC has a higher thromboembolic events (TEE) rate than the expected.METHODSBetween 2008 and 2021,…”
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Alectinib after failure to crizotinib in patients with ALK-positive non-small cell lung cancer: results from the Spanish early access program
Published in Oncotarget (15-06-2022)“…This retrospective observational study analyzed the clinical characteristics, treatment patterns and outcomes of 120 patients with advanced ALK-positive…”
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Clinical Activity of Afatinib in Patients With Non–Small-Cell Lung Cancer Harboring Uncommon EGFR Mutations: A Spanish Retrospective Multicenter Study
Published in Clinical lung cancer (01-09-2020)“…Uncommon epidermal growth factor receptor (EGFR) mutations (u-EGFRm) are a heterogeneous group of molecular alterations and have also been reported as…”
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A new role for circulating T follicular helper cells in humoral response to anti-PD-1 therapy
Published in Journal for immunotherapy of cancer (01-09-2020)“…BackgroundLung cancer is one of the most frequent malignancies in humans and is a major cause of death. A number of therapies aimed at reinforcing antitumor…”
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Effect of excess weight and immune-related adverse events on the efficacy of cancer immunotherapy with anti-PD-1 antibodies
Published in Oncoimmunology (01-01-2020)“…Immunotherapy is an effective treatment in advanced cancer, although predictors of response are limited. We studied whether excess weight influences the…”
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BRAF mutant non-small cell lung cancer and treatment with BRAF inhibitors
Published in Translational lung cancer research (01-06-2013)“…Inhibitors targeting active protein kinases, such as EGFR or ALK, have demonstrated significant efficacy in the treatment of lung cancer. Activating mutations…”
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LungBEAM: A prospective multicenter study to monitor stage IV NSCLC patients with EGFR mutations using BEAMing technology
Published in Cancer medicine (Malden, MA) (01-09-2021)“…Objectives The aim of LungBEAM was to determine the value of a novel epidermal growth factor receptor (EGFR) mutation test in blood based on BEAMing technology…”
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The Hippo effector YAP promotes resistance to RAF- and MEK-targeted cancer therapies
Published in Nature genetics (01-03-2015)“…Trever Bivona and colleagues show that the Hippo pathway effector YAP promotes resistance to RAF and MEK inhibitor therapy in multiple types of BRAF -mutant…”
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Clinical utility of plasma-based digital next-generation sequencing in oncogene-driven non-small-cell lung cancer patients with tyrosine kinase inhibitor resistance
Published in Lung cancer (Amsterdam, Netherlands) (01-08-2019)“…•Multicenter prospective study including 53 EGFR/ALK/ROS1-TKI-resistant patients.•Thirty-four patients (64%) had evidence of tumor-DNA shed for resistance…”
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Atezolizumab Plus Bevacizumab as First-line Treatment for Patients With Metastatic Nonsquamous Non-Small Cell Lung Cancer With High Tumor Mutation Burden: A Nonrandomized Controlled Trial
Published in JAMA oncology (01-03-2023)“…Antiangiogenic drug combinations with anti-programmed cell death 1 protein and anti-programmed cell death 1 ligand 1 (PD-L1) agents are a novel treatment…”
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Excess weight and anti-PD-1 immune checkpoint inhibitor’s outcomes in non-small cell lung cancer
Published in Clinical & translational oncology (01-11-2022)“…Purpose Immune checkpoint inhibitors are one of the most effective treatments available in advanced non-small cell lung cancer. However, at present, there are…”
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The S-REAL study: Spanish real-world data on unresectable stage III NSCLC patients treated with durvalumab after chemoradiotherapy
Published in Clinical & translational oncology (01-07-2024)“…Objectives The S-REAL study aimed to assess the effectiveness of durvalumab as consolidation therapy after definitive chemoradiotherapy (CRT) in a real-world…”
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Nivolumab-induced thyroid dysfunction in patients with lung cancer
Published in Endocrinologia, diabetes y nutricion (01-01-2019)“…Nivolumab is an anti-cancer monoclonal antibody that inhibits PD1 and modulates T-cell response. It has been shown to significantly improve survival in several…”
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PD-L1 testing and clinical management of newly diagnosed metastatic non-small cell lung cancer in Spain: MOREL study
Published in Lung cancer management (01-12-2021)“…To describe the clinical management and PD-L1 testing of patients with newly diagnosed stage IV non-small cell lung cancer (NSCLC) without driver mutations in…”
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Pemetrexed Safety and Pharmacokinetics in Patients with Third-Space Fluid
Published in Clinical cancer research (15-05-2010)“…Pemetrexed is established as first-line treatment with cisplatin for malignant pleural mesothelioma and advanced nonsquamous non-small-cell lung cancer (NSCLC)…”
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Molecular profiling by NGS upon progression disease in advanced stage NSCLC patients
Published in Journal of clinical oncology (20-05-2021)“…Abstract only e21196 Background: Non-small cells lung cancer (NSCLC) patients treated with Tyrosine Kinase Inhibitors (TKI) at first-line ultimately develop…”
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Clinical and molecular characteristics of the patients in the liquid biopsy study in mEGFR-NSCLC in a Spanish population (OPH-1)
Published in Journal of clinical oncology (20-05-2020)“…Abstract only e21515 Background: The liquid biopsy (LB) is an important tool in the diagnostic and follow up of the patients with non-small cell lung cancer…”
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