Search Results - "Sánchez‐Schmitz, Guzman"

Increased Micronuclei Frequency in Oral and Lingual Epithelium of Treated Diabetes Mellitus Patients by Ramos-Payán, Rosalío, Sánchez-Schmitz, Guzman, Romero Quintana, Jose Geovanni, Ayala Ham, Alfredo, García Jau, Rosa Alicia, Olimón-Andalón, Vicente, Aguilar-Medina, Maribel, Quintero Ojeda, Jesús Emilo, Silva-Benítez, Erika de Lourdes

“…Diabetes mellitus (DM) is a metabolic disease characterized by persistent high levels of glucose in plasma. Chronic hyperglycemia is thought to increase…”
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HLA Alleles are Genetic Markers for Susceptibility and Resistance towards Leprosy in a Mexican Mestizo Population by Aguilar‐Medina, Maribel, Escamilla‐Tilch, Monica, Frías‐Castro, Luis Octavio, Romero‐Quintana, Geovanni, Estrada‐García, Iris, Estrada‐Parra, Sergio, Granados, Julio, Arambula Meraz, Eliakym, Sánchez‐Schmitz, Guzman, Khader, Shabaana Abdul, Rangel‐Moreno, Javier, Ramos‐Payán, Rosalío

“…Summary Despite the use of multidrug therapy, leprosy remains endemic in some countries. The association of several human leucocyte antigen (HLA) alleles and…”
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Genetic Polymorphisms of Interleukin-1 Alpha and the Vitamin D Receptor in Mexican Mestizo Patients with Intervertebral Disc Degeneration by Estrada-Garcia, Iris, Sánchez-Schmitz, Guzman, Ramos-Payán, Rosalío, Picos-Cárdenas, Veronica, Osuna Ramírez, Ignacio, Arámbula Meraz, Eliakym, Romero Quintana, Jose Geovanni, Romero-Navarro, Jose Guillermo, Aguilar-Medina, Maribel, González Villareal, Dalia, Cervin Serrano, Salvador, Granados, Julio

“…Intervertebral disc degeneration (IDD) is the most common diagnosis in patients with back pain, a leading cause of musculoskeletal disability worldwide…”
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CD16+ and CD16− human blood monocyte subsets differentiate in vitro to dendritic cells with different abilities to stimulate CD4+ T cells by Sánchez-Torres, Carmen, García-Romo, Gina S., Cornejo-Cortés, Miguel A., Rivas-Carvalho, Amaranta, Sánchez-Schmitz, Guzmán

“…Experimental protocols for cancer immunotherapy include the utilization of autologous monocyte-derived dendritic cells (moDC) pulsed with tumor antigens…”
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Development of newborn and infant vaccines by Sanchez-Schmitz, Guzman, Levy, Ofer

“…Vaccines for early-life immunization are a crucial biomedical intervention to reduce global morbidity and mortality, yet their developmental path has been…”
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Toll-like receptor 8 agonist nanoparticles mimic immunomodulating effects of the live BCG vaccine and enhance neonatal innate and adaptive immune responses by Dowling, David J., PhD, Scott, Evan A., PhD, Scheid, Annette, MD, Bergelson, Ilana, BSc, Joshi, Sweta, PhD, Pietrasanta, Carlo, MD, Brightman, Spencer, BA, Sanchez-Schmitz, Guzman, MSc, PhD, Van Haren, Simon D., PhD, Ninković, Jana, PhD, Kats, Dina, BSc, Guiducci, Cristiana, PhD, de Titta, Alexandre, PhD, Bonner, Daniel K., PhD, Hirosue, Sachiko, PhD, Swartz, Melody A., PhD, Hubbell, Jeffrey A., PhD, Levy, Ofer, MD, PhD

“…Background Newborns display distinct immune responses, leaving them vulnerable to infections and impairing immunization. Targeting newborn dendritic cells…”
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Neonatal monocytes demonstrate impaired homeostatic extravasation into a microphysiological human vascular model by Sanchez-Schmitz, Guzman, Morrocchi, Elena, Cooney, Mitchell, Soni, Dheeraj, Khatun, Rahima, Palma, Paolo, Dowling, David J., Levy, Ofer

“…Infections are most frequent at the extremes of life, especially among newborns, reflecting age-specific differences in immunity. Monocytes maintain…”
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Human Newborn Monocytes Demonstrate Distinct BCG-Induced Primary and Trained Innate Cytokine Production and Metabolic Activation In Vitro by Angelidou, Asimenia, Diray-Arce, Joann, Conti, Maria-Giulia, Netea, Mihai G, Blok, Bastiaan A, Liu, Mark, Sanchez-Schmitz, Guzman, Ozonoff, Al, van Haren, Simon D, Levy, Ofer

“…Newborns exhibit distinct immune responses and are at high risk of infection. Neonatal immunization with BCG, the live attenuated vaccine against tuberculosis…”
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Microphysiologic Human Tissue Constructs Reproduce Autologous Age-Specific BCG and HBV Primary Immunization in vitro by Sanchez-Schmitz, Guzman, Stevens, Chad R, Bettencourt, Ian A, Flynn, Peter J, Schmitz-Abe, Klaus, Metser, Gil, Hamm, David, Jensen, Kristoffer J, Benn, Christine, Levy, Ofer

“…Current vaccine development disregards human immune ontogeny, relying on animal models to select vaccine candidates targeting human infants, who are at…”
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Hydrogel-Based Scaffolds in Oral Tissue Engineering by Ayala-Ham, Alfredo, López-Gutierrez, Jorge, Bermúdez, Mercedes, Aguilar-Medina, Maribel, Sarmiento-Sánchez, Juan Ignacio, López-Camarillo, César, Sanchez-Schmitz, Guzman, Ramos-Payan, Rosalio

“…Regenerative therapy in dentistry has gained interest given the complexity to restore dental and periodontal tissues with inert materials. The best approach…”
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Vascular Endothelium in Neonatal Sepsis: Basic Mechanisms and Translational Opportunities by Pietrasanta, Carlo, Pugni, Lorenza, Ronchi, Andrea, Bottino, Ilaria, Ghirardi, Beatrice, Sanchez-Schmitz, Guzman, Borriello, Francesco, Mosca, Fabio, Levy, Ofer

“…Neonatal sepsis remains a major health issue worldwide, especially for low-birth weight and premature infants, with a high risk of death and devastating…”
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Human in vitro modeling of adjuvant formulations demonstrates enhancement of immune responses to SARS-CoV-2 antigen by Doss-Gollin, Simon, Thomas, Sanya, Brook, Byron, Abedi, Kimia, Lebas, Célia, Auderset, Floriane, Lugo-Rodriguez, Yamile, Sanchez-Schmitz, Guzman, Dowling, David J., Levy, Ofer, van Haren, Simon D.

“…Adjuvants can enhance vaccine immunogenicity, but their mechanism of action is often incompletely understood, hampering rapid applicability for pandemic…”
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IL-6, IL-10 and TNF-α gene polymorphisms in preeclampsia: a case-control study in a Mexican population by Mora Palazuelos, Carlos Ernesto, Aguilar Medina, Elsa Maribel, Avendaño Felix, Mariana Melisa, Payán, Rosalio Ramos, Cortez, Mercedes Bermudez, Lara Avila, Leticia, Herrera Salazar, Adrian, Murillo Llanes, Joel, Sanchez-Schmitz, Guzmán, Romero Quintana, Jose Geovanni

“…We focused our study on examining the genotype and allele frequency of IL-6 (rs1800795), TNF-α (rs1800629) and IL-10 (rs1800872) single nucleotide…”
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The CD16(+) (FcgammaRIII(+)) subset of human monocytes preferentially becomes migratory dendritic cells in a model tissue setting by Randolph, Gwendalyn J, Sanchez-Schmitz, Guzman, Liebman, Ronald M, Schäkel, Knut

“…Much remains to be learned about the physiologic events that promote monocytes to become lymph-homing dendritic cells (DCs). In a model of transendothelial…”
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Biofunctionalization of hydrogel-based scaffolds for vascular tissue regeneration by López-Gutierrez, Jorge, Ramos-Payán, Rosalío, Ayala-Ham, Alfredo, Romero-Quintana, José Geovanni, Castillo-Ureta, Hipolito, Villegas-Mercado, Carlos, Bermúdez, Mercedes, Sanchez-Schmitz, Guzman, Aguilar-Medina, Maribel

“…Congenital and acquired tissular losses due to disease or trauma are a major world health problem. Regenerative therapy aims to fix damaged tissues by…”
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A single birth dose of Hepatitis B vaccine induces polyfunctional CD4 + T helper cells by Strandmark, Julia, Darboe, Alansana, Diray-Arce, Joann, Ben-Othman, Rym, Vignolo, Sofia M, Rao, Shun, Smolen, Kinga K, Leroux-Roels, Geert, Idoko, Olubukola T, Sanchez-Schmitz, Guzmán, Ozonoff, Al, Levy, Ofer, Kollmann, Tobias R, Marchant, Arnaud, Kampmann, Beate

“…A single birth-dose of Hepatitis B vaccine (HepB) can protect newborns from acquiring Hepatitis B infection through vertical transmission, though several…”
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Role of CCR8 and other chemokine pathways in the migration of monocyte-derived dendritic cells to lymph nodes by Qu, Chunfeng, Edwards, Emmerson W, Tacke, Frank, Angeli, Véronique, Llodrá, Jaime, Sanchez-Schmitz, Guzman, Garin, Alexandre, Haque, Nasreen S, Peters, Wendy, van Rooijen, Nico, Sanchez-Torres, Carmen, Bromberg, Jonathan, Charo, Israel F, Jung, Steffen, Lira, Sergio A, Randolph, Gwendalyn J

“…Studying the influence of chemokine receptors (CCRs) on monocyte fate may reveal information about which subpopulations of monocytes convert to dendritic cells…”
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Assessing the immunopotency of Toll-like receptor agonists in an in vitro tissue-engineered immunological model by Ma, Yifan, Poisson, Louis, Sanchez-Schmitz, Guzman, Pawar, Santosh, Qu, Chunfeng, Randolph, Gwendalyn J, Warren, William L, Mishkin, Eric M, Higbee, Russell G

“…The in vitro Peripheral Tissue Equivalent (PTE) module is a three-dimensional tissue-engineered endothelial cell/collagen matrix culture system, which has been…”
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Clinical Protocol for a Longitudinal Cohort Study Employing Systems Biology to Identify Markers of Vaccine Immunogenicity in Newborn Infants in The Gambia and Papua New Guinea by Idoko, Olubukola T, Smolen, Kinga K, Wariri, Oghenebrume, Imam, Abdulazeez, Shannon, Casey P, Dibassey, Tida, Diray-Arce, Joann, Darboe, Alansana, Strandmark, Julia, Ben-Othman, Rym, Odumade, Oludare A, McEnaney, Kerry, Amenyogbe, Nelly, Pomat, William S, van Haren, Simon, Sanchez-Schmitz, Guzmán, Brinkman, Ryan R, Steen, Hanno, Hancock, Robert E W, Tebbutt, Scott J, Richmond, Peter C, van den Biggelaar, Anita H J, Kollmann, Tobias R, Levy, Ofer, Ozonoff, Al, Kampmann, Beate

“…Infection contributes to significant morbidity and mortality particularly in the very young and in low- and middle-income countries. While vaccines are a…”
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Dynamic molecular changes during the first week of human life follow a robust developmental trajectory by Lee, Amy H., Shannon, Casey P., Amenyogbe, Nelly, Bennike, Tue B., Diray-Arce, Joann, Idoko, Olubukola T., Gill, Erin E., Ben-Othman, Rym, Pomat, William S., van Haren, Simon D., Cao, Kim-Anh Lê, Cox, Momoudou, Darboe, Alansana, Falsafi, Reza, Ferrari, Davide, Harbeson, Daniel J., He, Daniel, Bing, Cai, Hinshaw, Samuel J., Ndure, Jorjoh, Njie-Jobe, Jainaba, Pettengill, Matthew A., Richmond, Peter C., Ford, Rebecca, Saleu, Gerard, Masiria, Geraldine, Matlam, John Paul, Kirarock, Wendy, Roberts, Elishia, Malek, Mehrnoush, Sanchez-Schmitz, Guzmán, Singh, Amrit, Angelidou, Asimenia, Smolen, Kinga K., Brinkman, Ryan R., Ozonoff, Al, Hancock, Robert E. W., van den Biggelaar, Anita H. J., Steen, Hanno, Tebbutt, Scott J., Kampmann, Beate, Levy, Ofer, Kollmann, Tobias R.

“…Systems biology can unravel complex biology but has not been extensively applied to human newborns, a group highly vulnerable to a wide range of diseases. We…”
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