Search Results - "Sánchez‐Gómez, María Victoria"

GAT‐1 mediated GABA uptake in rat oligodendrocytes by Fattorini, Giorgia, Melone, Marcello, Sánchez‐Gómez, María Victoria, Arellano, Rogelio O., Bassi, Silvia, Matute, Carlos, Conti, Fiorenzo

“…Stimulated by the results of a recent paper on the effects of tiagabine, a selective inhibitor of the main GABA transporter GAT‐1, on oligodendrogenesis, we…”
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Glutamate-mediated glial injury: Mechanisms and clinical importance by Matute, Carlos, Domercq, María, Sánchez-Gómez, María-Victoria

“…Primary and/or secondary glial cell death can cause and/or aggravate human diseases of the central nervous system (CNS). Like neurons, glial cells are…”
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GABAB receptor agonist baclofen promotes central nervous system remyelination by Serrano‐Regal, Mari Paz, Bayón‐Cordero, Laura, Chara Ventura, Juan Carlos, Ochoa‐Bueno, Blanca I., Tepavcevic, Vanja, Matute, Carlos, Sánchez‐Gómez, María Victoria

“…Promoting remyelination is considered as a potential neurorepair strategy to prevent/limit the development of permanent neurological disability in patients…”
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Cannabidiol induces intracellular calcium elevation and cytotoxicity in oligodendrocytes by Mato, Susana, Victoria Sánchez-Gómez, María, Matute, Carlos

“…Heavy marijuana use has been linked to white matter histological alterations. However, the impact of cannabis constituents on oligodendroglial pathophysiology…”
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Excitotoxic damage to white matter by Matute, Carlos, Alberdi, Elena, Domercq, María, Sánchez‐Gómez, María‐Victoria, Pérez‐Samartín, Alberto, Rodríguez‐Antigüedad, Alfredo, Pérez‐Cerdá, Fernando

“…Glutamate kills neurons by excitotoxicity, which is caused by sustained activation of glutamate receptors. In recent years, it has been shown that glutamate…”
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Cytosolic zinc accumulation contributes to excitotoxic oligodendroglial death by Mato, Susana, Sánchez-Gómez, María Victoria, Bernal-Chico, Ana, Matute, Carlos

“…Dyshomeostasis of cytosolic Zn2+ is a critical mediator of neuronal damage during excitotoxicity. However, the role of this cation in oligodendrocyte…”
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Mangiferin and Morin Attenuate Oxidative Stress, Mitochondrial Dysfunction, and Neurocytotoxicity, Induced by Amyloid Beta Oligomers by Matute, Carlos, Solé-Domènech, Santiago, Quintela-López, Tania, Ortiz-Sanz, Carolina, Cavaliere, Fabio, Ruiz, Asier, Sánchez-Gómez, María Victoria, Alberdi, Elena, Capetillo-Zarate, Estibaliz

“…Amyloid beta- (Aβ-) mediated ROS overproduction disrupts intraneuronal redox balance and exacerbates mitochondrial dysfunction which leads to neuronal injury…”
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Expression and Function of GABA Receptors in Myelinating Cells by Serrano-Regal, Mari Paz, Bayón-Cordero, Laura, Ordaz, Rainald Pablo, Garay, Edith, Limon, Agenor, Arellano, Rogelio O, Matute, Carlos, Sánchez-Gómez, María Victoria

“…Myelin facilitates the fast transmission of nerve impulses and provides metabolic support to axons. Differentiation of oligodendrocyte progenitor cells (OPCs)…”
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GABA Receptor Agonists Protect From Excitotoxic Damage Induced by AMPA in Oligodendrocytes by Bayón-Cordero, Laura, Ochoa-Bueno, Blanca Isabel, Ruiz, Asier, Ozalla, Marina, Matute, Carlos, Sánchez-Gómez, María Victoria

“…Oligodendrocytes are the myelin forming cells of the central nervous system, and their vulnerability to excitotoxicity induced by glutamate contributes to the…”
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Expression of glutamate transporters in rat optic nerve oligodendrocytes by Domercq, María, Sánchez-Gómez, María Victoria, Areso, Pilar, Matute, Carlos

“…To investigate the role of glutamate transport in non‐synaptic glia, we characterized the expression of three major glutamate transporters (EAAC1, GLAST and…”
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Neuroprotection by two polyphenols following excitotoxicity and experimental ischemia by Gottlieb, Miroslav, Leal-Campanario, Rocío, Campos-Esparza, María Rosario, Sánchez-Gómez, María Victoria, Alberdi, Elena, Arranz, Amaia, Delgado-García, José María, Gruart, Agnès, Matute, Carlos

“…Brain ischemia induces neuronal loss which is caused in part by excitotoxicity and free radical formation. Here, we report that mangiferin and morin, two…”
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Inhibition of Casein Kinase 2 Protects Oligodendrocytes From Excitotoxicity by Attenuating JNK/p53 Signaling Cascade by Canedo-Antelo, Manuel, Serrano, Mari Paz, Manterola, Andrea, Ruiz, Asier, Llavero, Francisco, Mato, Susana, Zugaza, José Luis, Pérez-Cerdá, Fernando, Matute, Carlos, Sánchez-Gómez, María Victoria

“…Oligodendrocytes are highly vulnerable to glutamate excitotoxicity, a central mechanism involved in tissue damage in Multiple Sclerosis (MS). Sustained…”
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Caspase-Dependent and Caspase-Independent Oligodendrocyte Death Mediated by AMPA and Kainate Receptors by Sanchez-Gomez, Maria Victoria, Alberdi, Elena, Ibarretxe, Gaskon, Torre, Iratxe, Matute, Carlos

“…Oligodendrocytes are vulnerable to excitotoxic signals mediated by AMPA receptors and by high- and low-affinity kainate receptors. Here we investigated the…”
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Differential neuroprotective effects of 5'-deoxy-5'-methylthioadenosine by Moreno, Beatriz, Lopez, Iciar, Fernández-Díez, Begoña, Gottlieb, Miroslav, Matute, Carlos, Sánchez-Gómez, María Victoria, Domercq, María, Giralt, Albert, Alberch, Jordi, Collon, Kevin W, Zhang, Helen, Parent, Jack M, Teixido, Meritxell, Giralt, Ernest, Ceña, Valentín, Posadas, Inmaculada, Martínez-Pinilla, Eva, Villoslada, Pablo, Franco, Rafael

“…5'-deoxy-5'-methylthioadenosine (MTA) is an endogenous compound produced through the metabolism of polyamines. The therapeutic potential of MTA has been…”
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GABA B receptor agonist baclofen promotes central nervous system remyelination by Serrano-Regal, Mari Paz, Bayón-Cordero, Laura, Chara Ventura, Juan Carlos, Ochoa-Bueno, Blanca I, Tepavcevic, Vanja, Matute, Carlos, Sánchez-Gómez, María Victoria

“…Promoting remyelination is considered as a potential neurorepair strategy to prevent/limit the development of permanent neurological disability in patients…”
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PROTECTIVE ROLE OF GABAR AGONISTS ON MITOCHONDRIAL DYSFUNCTION INDUCED BY AMPA AND AΒ OLIGOMERS IN OLIGODENDROCYTES by Ochoa-Bueno, Blanca Isabel, Bayón-Cordero, Laura, Galbis-Gramage, Nuria, Ruiz, Asier, Alberdi, Elena, Sánchez-Gómez, María Victoria

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NEDDYLATION HAS A KEY ROLE IN OLIGODENDROCYTE MATURATION AND MYELINATION by Luengas-Escuza, Irene, Bayón-Cordero, Laura, Velasco, Sergio, Varela, Marta, Sánchez-Gómez, María Victoria, Matute, Carlos, Buendia, Izaskun, Woodhoo, Ashwin

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MODULATING GABAB RECEPTOR SIGNALING IN OLIGODENDROCYTES AS A THERAPEUTIC STRATEGY IN MULTIPLE SCLEROSIS by Bayón-Cordero, Laura, Ochoa-Bueno, Blanca Isabel, Rubio-López, Esther, Buendia, Izaskun, Bai, Xianshu, Kirchhoff, Frank, Sánchez-Gómez, María Victoria, Matute, Carlos

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AMYLOID BETA OLIGOMERS IMPAIR ENERGY METABOLISM IN OLIGODENDROCYTES by Galbis-Gramage, Nuria, Ochoa-Bueno, Blanca Isabel, Gaminde-Blasco, Adhara, Senovilla-Ganzo, Rodrigo, Garcia-Moreno, Fernando, Arranz, Amaia Mendiguren, Sánchez-Gómez, María Victoria, Alberdi, Elena

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Dual-specific Phosphatase-6 (Dusp6) and ERK Mediate AMPA Receptor-induced Oligodendrocyte Death by Domercq, Maria, Alberdi, Elena, Sánchez-Gómez, Maria Victoria, Ariz, Usue, Pérez-Samartín, Alberto, Matute, Carlos

“…Oligodendrocytes, the myelinating cells of the CNS, are highly vulnerable to glutamate excitotoxicity, a mechanism involved in tissue damage in multiple…”
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