Search Results - "Sánchez‐Fueyo, Alberto"
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Applicability, safety, and biological activity of regulatory T cell therapy in liver transplantation
Published in American journal of transplantation (01-04-2020)“…Regulatory T cells (Tregs) are a lymphocyte subset with intrinsic immunosuppressive properties that can be expanded in large numbers ex vivo and have been…”
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Biomarkers of Operational Tolerance After Liver Transplantation: Are We There Yet?
Published in Liver transplantation (01-01-2022)Get full text
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On minor histocompatibility antigens, mixed chimerism, and transplantation tolerance
Published in American journal of transplantation (01-03-2021)“…The article from Mahr et al. on page 968 clarifies the contributions of major and minor histocompatibility antigens to the induction of mixed chimerism and…”
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Immunologic Basis of Graft Rejection and Tolerance Following Transplantation of Liver or Other Solid Organs
Published in Gastroenterology (New York, N.Y. 1943) (01-01-2011)“…Transplantation of organs between genetically different individuals of the same species causes a T cell–mediated immune response that, if left unchecked,…”
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Impact of donor extracellular vesicle release on recipient cell “cross‐dressing” following clinical liver and kidney transplantation
Published in American journal of transplantation (01-07-2021)“…In several murine models of transplantation, the “cross‐dressing” of recipient antigen presenting cells (APCs) with intact donor major histocompatibility…”
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Prospective multicenter clinical trial of immunosuppressive drug withdrawal in stable adult liver transplant recipients
Published in Hepatology (Baltimore, Md.) (01-11-2013)“…Lifelong immunosuppression increases morbidity and mortality in liver transplantation. Discontinuation of immunosuppressive drugs could lessen this burden, but…”
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Hot‐topic debate on tolerance: Immunosuppression withdrawal
Published in Liver transplantation (01-11-2011)“…Key Points 1. Liver allografts exhibit intrinsic tolerogenic properties that result in their spontaneous acceptance in many experimental animal models. 2. In…”
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On the impact of hepatitis C virus and heterologous immunity on alloimmune responses following liver transplantation
Published in American journal of transplantation (01-01-2021)“…Virus‐induced heterologous immunity is considered a barrier to transplantation tolerance. Yet, hepatitis C (HCV)‐infected liver transplant (LT) patients…”
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Intra-graft expression of genes involved in iron homeostasis predicts the development of operational tolerance in human liver transplantation
Published in The Journal of clinical investigation (01-01-2012)“…Following organ transplantation, lifelong immunosuppressive therapy is required to prevent the host immune system from destroying the allograft. This can cause…”
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Usefulness of liver stiffness measurement during acute cellular rejection in liver transplantation
Published in Liver transplantation (01-03-2016)“…Liver stiffness measurement (LSM) is a useful method to estimate liver fibrosis and portal hypertension. The inflammatory process that takes place in…”
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Biomarkers of immunoregulatory status in stable liver transplant recipients undergoing weaning of immunosuppressive therapy
Published in Clinical immunology (Orlando, Fla.) (01-12-2010)“…Abstract Biomarkers that reflect immune response recovery and predict clinical events during withdrawal or minimization of immunosuppressive therapy have not…”
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Identification of operationally tolerant liver transplant recipients
Published in Liver transplantation (01-10-2010)“…KEY POINTS: (1) Liver allografts exhibit intrinsic tolerogenic properties that result in their spontaneous acceptance in many experimental animal models. (2)…”
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Tracking the Immunoregulatory Mechanisms Active During Allograft Tolerance
Published in The Journal of immunology (1950) (01-03-2002)“…Immunoregulatory mechanisms dependent on regulatory CD4+ T cells are believed to be critical in the maintenance of peripheral tolerance to allografts. However,…”
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Specificity of CD4+CD25+ Regulatory T Cell Function in Alloimmunity
Published in The Journal of immunology (1950) (01-01-2006)“…CD4+CD25+ regulatory T cells (TRegs) are critical for the acquisition of peripheral allograft tolerance. However, it is unclear whether TRegs are capable of…”
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Biomarkers of immune tolerance in liver transplantation
Published in Human immunology (01-05-2018)“…The liver exhibits intrinsic immune tolerogenic properties that contribute to a unique propensity toward spontaneous acceptance when transplanted, both in…”
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Hepatitis B immunoglobulin discontinuation followed by hepatitis B virus vaccination: A new strategy in the prophylaxis of hepatitis B virus recurrence after liver transplantation
Published in Hepatology (Baltimore, Md.) (01-02-2000)“…It is widely agreed that hepatitis B virus immunoglobulin (HBIG) should be administered for at least 12 months to patients transplanted for hepatitis B virus…”
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Can we predict allograft tolerance in experimental animal models of transplantation?
Published in Liver transplantation (01-04-2012)Get full text
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Banff 2019 Meeting Report: Molecular diagnostics in solid organ transplantation–Consensus for the Banff Human Organ Transplant (B‐HOT) gene panel and open source multicenter validation
Published in American journal of transplantation (01-09-2020)“…This meeting report from the XV Banff conference describes the creation of a multiorgan transplant gene panel by the Banff Molecular Diagnostics Working Group…”
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Low dose interleukin-2 selectively expands circulating regulatory T cells but fails to promote liver allograft tolerance in humans
Published in Journal of hepatology (01-01-2023)“…CD4+CD25+Foxp3+ regulatory T cells (Tregs) are essential to maintain immunological tolerance and have been shown to promote liver allograft tolerance in both…”
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Advances in Liver Transplantation: where are we in the pursuit of transplantation tolerance?
Published in European journal of immunology (01-10-2021)“…Liver transplantation is the ultimate treatment option for end‐stage liver disease. Breakthroughs in surgical practice and immunosuppression have seen…”
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