Search Results - "Sánchez‐Castillo, Anaís"
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The transcribed pseudogene RPSAP52 enhances the oncofetal HMGA2-IGF2BP2-RAS axis through LIN28B-dependent and independent let-7 inhibition
Published in Nature communications (04-09-2019)“…One largely unknown question in cell biology is the discrimination between inconsequential and functional transcriptional events with relevant regulatory…”
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Understanding serine and glycine metabolism in cancer: a path towards precision medicine to improve patient’s outcomes
Published in Discover. Oncology (13-11-2024)“…In this perspective, we highlight and reflect on the current knowledge with respect to serine/glycine metabolism in cancer, therapeutic resistance, and…”
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The transcribed ultraconserved region uc.160+ enhances processing and A‐to‐I editing of the miR‐376 cluster: hypermethylation improves glioma prognosis
Published in Molecular oncology (01-02-2022)“…Transcribed ultraconserved regions (T‐UCRs) are noncoding RNAs derived from DNA sequences that are entirely conserved across species. Their expression is…”
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Sertraline/chloroquine combination therapy to target hypoxic and immunosuppressive serine/glycine synthesis-dependent glioblastomas
Published in Oncogenesis (New York, NY) (13-11-2024)“…The serine/glycine (ser/gly) synthesis pathway branches from glycolysis and is hyperactivated in approximately 30% of cancers. In ~13% of glioblastoma cases,…”
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Linking Serine/Glycine Metabolism to Radiotherapy Resistance
Published in Cancers (10-03-2021)“…The activation of de novo serine/glycine biosynthesis in a subset of tumors has been described as a major contributor to tumor pathogenesis, poor outcome, and…”
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Targeting serine/glycine metabolism improves radiotherapy response in non-small cell lung cancer
Published in British journal of cancer (09-03-2024)“…Background Lung cancer is the most lethal cancer, and 85% of cases are classified as non-small cell lung cancer (NSCLC). Metabolic rewiring is a cancer…”
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Abstract 1819: Non-coding RNAs as key players for understanding oncogenic pathways in ovarian cancer: Studying new therapeutic strategies
Published in Cancer research (Chicago, Ill.) (01-07-2019)“…The largest part of the human genome is transcribed into non-coding RNAs (ncRNAs) which are functional transcripts displaying relevant roles in many biological…”
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1866: Targeting serine/glycine metabolism improves radiotherapy response in Non-Small Cell Lung Cancer
Published in Radiotherapy and oncology (01-05-2024)Get full text
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Correction: Targeting serine/glycine metabolism improves radiotherapy response in non-small cell lung cancer
Published in British journal of cancer (09-03-2024)Get full text
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