Search Results - "Sánchez, Oliberto"
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Host cell factors involved in classical swine fever virus entry
Published in Veterinary research (Paris) (01-12-2023)“…Abstract Classical swine fever virus (CSFV) is an ancient pathogen that continues to pose a threat to animal agriculture worldwide. The virus belongs to the…”
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Nimotuzumab, an Antitumor Antibody that Targets the Epidermal Growth Factor Receptor, Blocks Ligand Binding while Permitting the Active Receptor Conformation
Published in Cancer research (Chicago, Ill.) (15-07-2009)“…Overexpression of the epidermal growth factor (EGF) receptor (EGFR) in cancer cells correlates with tumor malignancy and poor prognosis for cancer patients…”
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3
In vitro immunomodulatory activities of peptides derived from Salmo salar NK-lysin and cathelicidin in fish cells
Published in Fish & shellfish immunology (01-05-2019)“…Antimicrobial peptides (AMPs) are amphipathic peptides, which play an important role in innate defence. These peptides are gene-encoded and either…”
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4
Recombinant Subunit Vaccine Candidate against the Bovine Viral Diarrhea Virus
Published in International journal of molecular sciences (10-08-2024)“…Multivalent live-attenuated or inactivated vaccines are often used to control the bovine viral diarrhea disease (BVD). Still, they retain inherent…”
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5
Chitosan Microparticles Enhance the Intestinal Release and Immune Response of an Immune Stimulant Peptide in Oncorhynchus mykiss
Published in International journal of molecular sciences (01-10-2023)“…The aquaculture industry is constantly increasing its fish production to provide enough products to maintain fish consumption worldwide. However, the increased…”
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6
Structure-based design and construction of a synthetic phage display nanobody library
Published in BMC research notes (29-03-2022)“…To design and construct a new synthetic nanobody library using a structure-based approach that seeks to maintain high protein stability and increase the number…”
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Design and characterization of a novel dimeric blood–brain barrier penetrating TNFα inhibitor
Published in Proteins, structure, function, and bioinformatics (01-11-2021)“…Tumor necrosis factor‐alpha (TNFα) inhibitors could prevent neurological disorders systemically, but their design generally relies on molecules unable to cross…”
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Design and Construction of a Synthetic Nanobody Library: Testing Its Potential with a Single Selection Round Strategy
Published in Molecules (Basel, Switzerland) (25-04-2023)“…Nanobodies (Nbs) are single domain antibody fragments derived from heavy-chain antibodies found in members of the Camelidae family. They have become a relevant…”
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New insight into the biological activity of Salmo salar NK-lysin antimicrobial peptides
Published in Frontiers in immunology (09-04-2024)“…NK-lysin is a potent antimicrobial peptide (AMP) with antimicrobial activity against bacteria, fungi, viruses, and parasites. NK-lysin is a type of granulysin,…”
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10
First report of bovine viral diarrhea virus subgenotypes 1d and 1e in southern Chile
Published in Virology journal (07-09-2023)“…Abstract Bovine viral diarrhea virus (BVDV) affects cattle worldwide causing severe productive and economic loss. In this study, we investigated the…”
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A trivalent TNF‐R2 as a new tumor necrosis factor alpha‐blocking molecule
Published in Proteins, structure, function, and bioinformatics (01-11-2021)“…The neutralization of tumor necrosis factor alpha (TNFα) with biopharmaceuticals is a successful therapy for inflammatory diseases. Currently, one of the main…”
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Selecting Nanobodies Specific for the Epidermal Growth Factor from a Synthetic Nanobody Library
Published in Molecules (Basel, Switzerland) (12-05-2023)“…The epidermal growth factor (EGF) is one of the most critical ligands of the EGF receptor (EGFR), a well-known oncogene frequently overexpressed in cancerous…”
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New insights on the interaction mechanism of rhTNFα with its antagonists Adalimumab and Etanercept
Published in Biochemical journal (18-09-2020)“…TNFα is a pro-inflammatory cytokine that is a therapeutic target for inflammatory autoimmune disorders. Thus, TNFα antagonists are successfully used for the…”
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Design and functional characterization of Salmo salar TLR5 agonist peptides derived from high mobility group B1 acidic tail
Published in Fish & shellfish immunology (01-03-2024)“…Toll-like receptor 5 (TLR5) responds to the monomeric form of flagellin and induces the MyD88-depending signaling pathway, activating proinflammatory…”
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15
Effects of recombinant FSH (bscrFSH) and pituitary FSH (FSH-p) on embryo production in superovulated dairy heifers inseminated with unsorted and sex-sorted semen
Published in Animal reproduction science (01-05-2023)“…Superovulation is a drug-based method used in cattle to stimulate the ovarian folliculogenesis and the number of oocytes and transferable embryos. The present…”
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Effects of Extra-Long-Acting Recombinant Bovine FSH (bscrFSH) on Cattle Superovulation
Published in Animals (Basel) (09-01-2022)“…Over the last few years, several commercial FSH products have been developed for cattle superovulation (SOV) purposes in Multiple Ovulation and Embryo Transfer…”
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Atomic Structure and Biochemical Characterization of an RNA Endonuclease in the N Terminus of Andes Virus L Protein
Published in PLoS pathogens (01-06-2016)“…Andes virus (ANDV) is a human-pathogenic hantavirus. Hantaviruses presumably initiate their mRNA synthesis by using cap structures derived from host cell…”
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Polyethylenimine-Based Transfection Method as a Simple and Effective Way to Produce Recombinant Lentiviral Vectors
Published in Applied biochemistry and biotechnology (01-06-2009)“…HIV-1-derived lentiviral vectors (LvV) are within the most attractive gene delivery vehicles in the context of both dividing and quiescent cells. LvV is…”
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19
Lectin-like oxidized LDL receptor-1 is an enhancer of tumor angiogenesis in human prostate cancer cells
Published in PloS one (29-08-2014)“…Altered expression and function of lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) has been associated with several diseases such as…”
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New Formulation of a Subunit Vaccine Candidate against Lawsonia intracellularis Increases Humoral and Cellular Immune Responses
Published in Vaccines (Basel) (04-12-2023)“…Previously, we designed a subunit vaccine candidate based on three antigens with promising results in pigs. In this study, antigens were produced individually…”
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