Search Results - "Sánchez, Lucía"

An anti-EGFR antibody-drug conjugate overcomes resistance to HER2-targeted drugs by Gandullo-Sánchez, Lucía, Pandiella, Atanasio

“…Trastuzumab-emtansine (T-DM1) is an antibody-drug conjugate (ADC) that was approved in 2013 to treat HER2+ breast cancer. Despite its efficacy in the clinic,…”
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HER3 in cancer: from the bench to the bedside by Gandullo-Sánchez, Lucía, Ocaéa, Alberto, Pandiella, Atanasio

“…Abstract The HER3 protein, that belongs to the ErbB/HER receptor tyrosine kinase (RTK) family, is expressed in several types of tumors. That fact, together…”
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Novel ADCs and Strategies to Overcome Resistance to Anti-HER2 ADCs by Díaz-Rodríguez, Elena, Gandullo-Sánchez, Lucía, Ocaña, Alberto, Pandiella, Atanasio

“…During recent years, a number of new compounds against HER2 have reached clinics, improving the prognosis and quality of life of HER2-positive breast cancer…”
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Generation of Antibody-Drug Conjugate Resistant Models by Gandullo-Sánchez, Lucía, Ocaña, Alberto, Pandiella, Atanasio

“…In the last 20 years, antibody-drug conjugates (ADCs) have been incorporated into the oncology clinic as treatments for several types of cancer. So far, the…”
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Increased functional connectivity patterns in mild Alzheimer's disease: A rsfMRI study by Penalba-Sánchez, Lucía, Oliveira-Silva, Patrícia, Sumich, Alexander Luke, Cifre, Ignacio

“…Alzheimer's disease (AD) is the most common age-related neurodegenerative disorder. In view of our rapidly aging population, there is an urgent need to…”
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Endometrial cancer and simultaneous pregnancy, an unusual combination. Case report by Vanesa, Delso Vicente, Lucía, Sánchez‐Barderas, Mar, Ramírez, Jesús, Coronado Pluvio

“…Abstract Uterine cancer is the fourth most common cancer in women. Declining fertility, combined with increasing overweight and diabetes, might be some of the…”
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Enhancing Self-Esteem and Body Image of Breast Cancer Women through Interventions: A Systematic Review by Morales-Sánchez, Lucía, Luque-Ribelles, Violeta, Gil-Olarte, Paloma, Ruiz-González, Paula, Guil, Rocío

“…Breast Cancer (BC) is the most common neoplasm in women worldwide, considered a global public health problem. Among BC women, some of the most common…”
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Dietary Patterns, Bone Mineral Density, and Risk of Fractures: A Systematic Review and Meta-Analysis by Denova-Gutiérrez, Edgar, Méndez-Sánchez, Lucía, Muñoz-Aguirre, Paloma, Tucker, Katherine L, Clark, Patricia

“…The aim of this systematic review was to assess the evidence on the relation between dietary patterns, bone mineral density (BMD), and risk of fracture in…”
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A 3D taphonomic model of long bone modification by lions in medium-sized ungulate carcasses by Domínguez-Rodrigo, Manuel, Gidna, Agness, Baquedano, Enrique, Cobo-Sánchez, Lucía, Mora, Rocio, Courtenay, Lloyd A., Gonzalez-Aguilera, Diego, Mate-Gonzalez, Miguel A., Prieto-Herráez, Diego

“…Here, we present the first three-dimensional taphonomic analysis of a carnivore-modified assemblage at the anatomical scale of the appendicular skeleton. A…”
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Lineage Decision-Making within Normal Haematopoietic and Leukemic Stem Cells by Brown, Geoffrey, Sánchez, Lucía, Sánchez-García, Isidro

“…To produce the wide range of blood and immune cell types, haematopoietic stem cells can "choose" directly from the entire spectrum of blood cell fate-options…”
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Analysis of HubP-dependent cell pole protein targeting in Vibrio cholerae uncovers novel motility regulators by Altinoglu, Ipek, Abriat, Guillaume, Carreaux, Alexis, Torres-Sánchez, Lucía, Poidevin, Mickaël, Krasteva, Petya Violinova, Yamaichi, Yoshiharu

“…In rod-shaped bacteria, the emergence and maintenance of long-axis cell polarity is involved in key cellular processes such as cell cycle, division,…”
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CRISPR/Cas9-Directed Gene Trap Constitutes a Selection System for Corrected BCR/ABL Leukemic Cells in CML by Vuelta, Elena, Ordoñez, José L., Sanz, David J., Ballesteros, Sandra, Hernández-Rivas, Jesús M., Méndez-Sánchez, Lucía, Sánchez-Martín, Manuel, García-Tuñón, Ignacio

“…Chronic myeloid leukaemia (CML) is a haematological neoplasm driven by the BCR/ABL fusion oncogene. The monogenic aspect of the disease and the feasibility of…”
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Classification of Sleep Quality and Aging as a Function of Brain Complexity: A Multiband Non-Linear EEG Analysis by Penalba-Sánchez, Lucía, Silva, Gabriel, Crook-Rumsey, Mark, Sumich, Alexander, Rodrigues, Pedro Miguel, Oliveira-Silva, Patrícia, Cifre, Ignacio

“…Understanding and classifying brain states as a function of sleep quality and age has important implications for developing lifestyle-based interventions…”
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Mass Spectrometric Fingerprints of Organic Compounds in Sulfate-Rich Ice Grains: Implications for Europa Clipper by Napoleoni, Maryse, Klenner, Fabian, Hortal Sánchez, Lucía, Khawaja, Nozair, Hillier, Jon K., Gudipati, Murthy S., Hand, Kevin P., Kempf, Sascha, Postberg, Frank

“…The surface ice of Europa is known to contain high proportions of inorganic material that could heavily influence the compositional analysis of organic…”
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Early Pleistocene faunivorous hominins were not kleptoparasitic, and this impacted the evolution of human anatomy and socio-ecology by Domínguez-Rodrigo, Manuel, Baquedano, Enrique, Organista, Elia, Cobo-Sánchez, Lucía, Mabulla, Audax, Maskara, Vivek, Gidna, Agness, Pizarro-Monzo, Marcos, Aramendi, Julia, Galán, Ana Belén, Cifuentes-Alcobendas, Gabriel, Vegara-Riquelme, Marina, Jiménez-García, Blanca, Abellán, Natalia, Barba, Rebeca, Uribelarrea, David, Martín-Perea, David, Diez-Martin, Fernando, Maíllo-Fernández, José Manuel, Rodríguez-Hidalgo, Antonio, Courtenay, Lloyd, Mora, Rocío, Maté-González, Miguel Angel, González-Aguilera, Diego

“…Humans are unique in their diet, physiology and socio-reproductive behavior compared to other primates. They are also unique in the ubiquitous adaptation to…”
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Breast Cancer and Resilience: The Controversial Role of Perceived Emotional Intelligence by Guil, Rocio, Ruiz-González, Paula, Merchán-Clavellino, Ana, Morales-Sánchez, Lucía, Zayas, Antonio, Gómez-Molinero, Rocio

“…Cancer is a chronic disease that causes the most deaths in the world, being a public health problem nowadays. Even though breast cancer affects the daily lives…”
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Osteolytic Lesions in a Sub-Adult Loggerhead Sea Turtle ( Caretta caretta ): A Case Report by Peña Pascucci, Ignacio, Pernas Mozas, Susana, Garrido Sánchez, Lucía

“…Osteolytic lesions in loggerhead sea turtles ( ) during rehabilitation are attributed to multiple causes, including gas embolism, hypothermia, and…”
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Sabertooth carcass consumption behavior and the dynamics of Pleistocene large carnivoran guilds by Domínguez-Rodrigo, Manuel, Egeland, Charles P., Cobo-Sánchez, Lucía, Baquedano, Enrique, Hulbert, Richard C.

“…Apex predators play an important role in the top-down regulation of ecological communities. Their hunting and feeding behaviors influence, respectively, prey…”
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Effect of Spanish‐style processing on the quality attributes of HydroSOStainable green olives by Sánchez‐Rodríguez, Lucía, Corell, Mireia, Hernández, Francisca, Sendra, Esther, Moriana, Alfonso, Carbonell‐Barrachina, Ángel A

“…Background Three treatments of regulated deficit irrigation (RDI) were assayed on olive trees for table olive production. RDI provides hydroSOStainable crops…”
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Reproductive aging and telomeres: Are women and men equally affected? by Chico-Sordo, Lucía, Córdova-Oriz, Isabel, Polonio, Alba María, S-Mellado, Lucía Sánchez, Medrano, Marta, García-Velasco, Juan Antonio, Varela, Elisa

“…•Recent data support the notion that telomere attrition is involved in reproductive aging, which happens differently in women and men.•Telomere aging is…”
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