Telephonic back-up improves antibiotic compliance in acute tonsillitis/pharyngitis

Telephonic back-up improves antibiotic compliance in acute tonsillitis/pharyngitis

A randomised clinical trial was devised to establish whether telephonic back-up added to educational strategy and improved compliance with antibiotic treatment in acute tonsillitis/pharyngitis compared with educational strategy only. The intervention group was given a telephone call on the fourth da...

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Bibliographic Details
Published in:International journal of antimicrobial agents Vol. 23; no. 2; pp. 138 - 143
Main Authors: Urién, A.Molinos, Guillén, V.F.Gil, Beltrán, D.Orozco, Pinzotas, C.López-Quintana, Pérez, E.Romero, Arocena, M.Oyarzabal, Sánchez, J.Merino
Format: Journal Article
Language:English
Published: London Elsevier B.V 01-02-2004
Amsterdam Elsevier
New York, NY
Subjects:
Acute Disease
Amoxicillin - administration & dosage
Amoxicillin - therapeutic use
Anti-Bacterial Agents - administration & dosage
Anti-Bacterial Agents - therapeutic use
Antibacterial agents
Antibiotics. Antiinfectious agents. Antiparasitic agents
Biological and medical sciences
Health Education
Humans
Medical sciences
Patient Compliance
Pharmacology. Drug treatments
Pharyngitis - drug therapy
Single-Blind Method
Telephone
Telephonic back-up
Tonsillitis - drug therapy
Tonsillitis/pharyngitis
Treatment Outcome
Telephonic back-up
Patient compliance
Tonsillitis/pharyngitis
Human
Acute
Tonsillitis
Drug compliance
Antibiotic
Chemotherapy
Treatment
Telephone call
ENT disease
Pharynx disease
Pharyngitis
Antibacterial agent
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Description
Summary:A randomised clinical trial was devised to establish whether telephonic back-up added to educational strategy and improved compliance with antibiotic treatment in acute tonsillitis/pharyngitis compared with educational strategy only. The intervention group was given a telephone call on the fourth day after the start of therapy. There were 64 patients in each group (intervention and control). The criterion for evaluating the compliance was to count the tablets in a spot-check at the patient’s house. A tablet count of 80–110% defined good compliance. The effect of the intervention was calculated according to the indicators: absolute risk reduction (ARR), relative risk reduction (RRR) and number needed to treat (NNT). A good compliance percentage was 66.1% (57.7–74.5%) and was significantly higher in the intervention group (78.3%) than in the control group (54.1%) ( P=0.005). Indicators of clinical relevance after the intervention were ARR: 24.2%; RRR: 52.7%; NNT: 4.13. In conclusion telephonic back-up significantly improved the compliance obtained by educational strategy only. It should be used in clinical practice.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
ObjectType-News-3
content type line 23
ISSN:0924-8579
1872-7913
DOI:10.1016/j.ijantimicag.2003.06.008