Search Results - "Sánchez, Elisabeth"

Expression of Gls and Gls2 glutaminase isoforms in astrocytes by Cardona, Carolina, Sánchez-Mejías, Elisabeth, Dávila, José C., Martín-Rufián, Mercedes, Campos-Sandoval, José A., Vitorica, Javier, Alonso, Francisco J., Matés, José M., Segura, Juan A., Norenberg, Michael D., Rama Rao, Kakulavarapu V., Jayakumar, Arumugan R., Gutiérrez, Antonia, Márquez, Javier

“…The expression of glutaminase in glial cells has been a controversial issue and matter of debate for many years. Actually, glutaminase is essentially…”
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The ABO blood group genotype and factor VIII levels as independent risk factors for venous thromboembolism by Tirado, Isabel, Mateo, José, Soria, José Manuel, Oliver, Arturo, Martínez-Sánchez, Elisabeth, Vallvé, Cristina, Borrell, Monserrat, Urrutia, Teresa, Fontcuberta, Jordi

“…Factor VIII (FVIII), von Willebrand factor (vWF) and the ABO blood groups have been associated with thrombosis. The ABO locus has functional effects on vWF and…”
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A new locus on chromosome 18 that influences normal variation in activated protein C resistance phenotype and factor VIII activity and its relation to thrombosis susceptibility by Soria, José Manuel, Almasy, Laura, Souto, Joan Carles, Buil, Alfonso, Martı́nez-Sánchez, Elisabeth, Mateo, José, Borrell, Montserrat, Stone, William H., Lathrop, Mark, Fontcuberta, Jordi, Blangero, John

“…Activated protein C resistance (APCR) is the most prevalent risk factor for thrombosis, accounting for 20% to 60% of familial thrombophilia. A mutation in the…”
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Medicinal Chemistry Driven Approaches Toward Novel and Selective Serotonin 5-HT6 Receptor Ligands by Holenz, Jörg, Mercè, Ramon, Díaz, José Luis, Guitart, Xavier, Codony, Xavier, Dordal, Alberto, Romero, Gonzalo, Torrens, Antoni, Mas, Josep, Andaluz, Blas, Hernández, Susana, Monroy, Xavier, Sánchez, Elisabeth, Hernández, Enrique, Pérez, Raquel, Cubí, Roger, Sanfeliu, Olga, Buschmann, Helmut

“…Based on a medicinal chemistry guided hypothetical pharmacophore model, novel series of indolyl sulfonamides have been designed and prepared as selective and…”
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Phagocytic clearance of presynaptic dystrophies by reactive astrocytes in Alzheimer's disease by Gomez‐Arboledas, Angela, Davila, Jose C., Sanchez‐Mejias, Elisabeth, Navarro, Victoria, Nuñez‐Diaz, Cristina, Sanchez‐Varo, Raquel, Sanchez‐Mico, Maria Virtudes, Trujillo‐Estrada, Laura, Fernandez‐Valenzuela, Juan Jose, Vizuete, Marisa, Comella, Joan X., Galea, Elena, Vitorica, Javier, Gutierrez, Antonia

“…Reactive astrogliosis, a complex process characterized by cell hypertrophy and upregulation of components of intermediate filaments, is a common feature in…”
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Amyloid‐β impairs the phagocytosis of dystrophic synapses by astrocytes in Alzheimer's disease by Sanchez‐Mico, Maria V., Jimenez, Sebastian, Gomez‐Arboledas, Angela, Muñoz‐Castro, Clara, Romero‐Molina, Carmen, Navarro, Victoria, Sanchez‐Mejias, Elisabeth, Nuñez‐Diaz, Cristina, Sanchez‐Varo, Raquel, Galea, Elena, Davila, José C., Vizuete, Marisa, Gutierrez, Antonia, Vitorica, Javier

“…Reactive astrocytes and dystrophic neurites, most aberrant presynaptic elements, are found surrounding amyloid‐β plaques in Alzheimer's disease (AD). We have…”
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Major reduction in AIDS-mortality inequalities after HAART: The importance of absolute differences in evaluating interventions by Regidor, Enrique, Sánchez, Elisabeth, de la Fuente, Luis, Luquero, Francisco J., de Mateo, Salvador, Domínguez, Vicente

“…This study estimates the magnitude of inequalities in AIDS mortality in the period when highly active antiretroviral therapy (HAART) was introduced and after…”
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Distinct disease‐sensitive GABAergic neurons in the perirhinal cortex of Alzheimer's mice and patients by Sanchez‐Mejias, Elisabeth, Nuñez‐Diaz, Cristina, Sanchez‐Varo, Raquel, Gomez‐Arboledas, Angela, Garcia‐Leon, Juan Antonio, Fernandez‐Valenzuela, Juan Jose, Mejias‐Ortega, Marina, Trujillo‐Estrada, Laura, Baglietto‐Vargas, David, Moreno‐Gonzalez, Ines, Davila, Jose Carlos, Vitorica, Javier, Gutierrez, Antonia

“…Neuronal loss is the best neuropathological substrate that correlates with cortical atrophy and dementia in Alzheimer's disease (AD). Defective GABAergic…”
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A proposal of measures for monitoring social disparities in health using AIDS and liver disease mortality before and after HAART by Regidor, Enrique, Sánchez, Elisabeth, de la Fuente, Luis, Santos, Juana M, Martínez, David

“…To assess the more appropriate measures for monitoring health differences and evaluating the impact of interventions based on the real burden of the health…”
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Human herpesvirus-8 in blood donors in Spain by Alcalde, Francisco Javier Luquero, Sanz, José Javier Castrodeza, Bouza, Jose Maria Eiros, De Lejarazu Leonardo, Raúl Ortiz, Padilla, Elisabeth Sánchez

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Short-Term Therapeutic Adherence of Hospitalized Older Patients with Oropharyngeal Dysphagia after an Education Intervention: Analysis of Compliance Rates, Risk Factors and Associated Complications by Mateos-Nozal, Jesús, Sánchez García, Elisabeth, Montero-Errasquín, Beatriz, Romero Rodríguez, Estela, Cruz-Jentoft, Alfonso J

“…Oropharyngeal dysphagia (OD) is associated with adverse outcomes that require a multidisciplinary approach with different strategies. Our aim was to assess the…”
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Prediction of Susceptibility to First-Line Tuberculosis Drugs by DNA Sequencing by Allix-Béguec, Caroline, Arandjelovic, Irena, Bi, Lijun, Beckert, Patrick, Bonnet, Maryline, Bradley, Phelim, Cabibbe, Andrea M, Cancino-Muñoz, Irving, Caulfield, Mark J, Chaiprasert, Angkana, Cirillo, Daniela M, Clifton, David A, Comas, Iñaki, Crook, Derrick W, De Filippo, Maria R, de Neeling, Han, Diel, Roland, Drobniewski, Francis A, Faksri, Kiatichai, Farhat, Maha R, Fleming, Joy, Fowler, Philip, Fowler, Tom A, Gao, Qian, Gardy, Jennifer, Gascoyne-Binzi, Deborah, Gibertoni-Cruz, Ana-Luiza, Gil-Brusola, Ana, Golubchik, Tanya, Gonzalo, Ximena, Grandjean, Louis, He, Guangxue, Guthrie, Jennifer L, Hoosdally, Sarah, Hunt, Martin, Iqbal, Zamin, Ismail, Nazir, Johnston, James, Khanzada, Faisal M, Khor, Chiea C, Kohl, Thomas A, Kong, Clare, Lipworth, Sam, Liu, Qingyun, Maphalala, Gugu, Martinez, Elena, Mathys, Vanessa, Merker, Matthias, Miotto, Paolo, Mistry, Nerges, Moore, David A J, Murray, Megan, Niemann, Stefan, Omar, Shaheed V, Ong, Rick T-H, Peto, Tim E A, Posey, James E, Prammananan, Therdsak, Pym, Alexander, Rodrigues, Camilla, Rodrigues, Mabel, Rodwell, Timothy, Rossolini, Gian M, Sánchez Padilla, Elisabeth, Schito, Marco, Shen, Xin, Shendure, Jay, Sintchenko, Vitali, Sloutsky, Alex, Smith, E Grace, Snyder, Matthew, Soetaert, Karine, Starks, Angela M, Supply, Philip, Suriyapol, Prapat, Tahseen, Sabira, Tang, Patrick, Teo, Yik-Ying, Thuong, Thuong N T, Thwaites, Guy, Tortoli, Enrico, van Soolingen, Dick, Walker, A Sarah, Walker, Timothy M, Wilcox, Mark, Wilson, Daniel J, Wyllie, David, Yang, Yang, Zhang, Hongtai, Zhao, Yanlin, Zhu, Baoli

“…Proper treatment of tuberculosis requires a combination of drugs to which the causative organism is susceptible. In this report, genotypic assessment of…”
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Synthesis of New Benzoxazinone Derivatives as Neuropeptide Y5 Antagonists for the Treatment of Obesity by Torrens, Antoni, Mas, Josep, Port, Adriana, Castrillo, José Aurelio, Sanfeliu, Olga, Guitart, Xavier, Dordal, Alberto, Romero, Gonzalo, Fisas, Ma Angeles, Sánchez, Elisabeth, Hernández, Enrique, Pérez, Pilar, Pérez, Raquel, Buschmann, Helmut

“…Screening of our internal chemical collection against the neuropeptide Y5 (NPY Y5) receptor allowed the identification of a benzoxazine derivative 5f as a hit…”
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Soluble phospho-tau from Alzheimer’s disease hippocampus drives microglial degeneration by Sanchez-Mejias, Elisabeth, Navarro, Victoria, Jimenez, Sebastian, Sanchez-Mico, Maria, Sanchez-Varo, Raquel, Nuñez-Diaz, Cristina, Trujillo-Estrada, Laura, Davila, Jose Carlos, Vizuete, Marisa, Gutierrez, Antonia, Vitorica, Javier

“…The role of microglial cells in the development and progression of Alzheimer’s disease (AD) has not been elucidated. Here, we demonstrated the existence of a…”
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Microglia in Alzheimer's Disease: Activated, Dysfunctional or Degenerative by Navarro, Victoria, Sanchez-Mejias, Elisabeth, Jimenez, Sebastian, Muñoz-Castro, Clara, Sanchez-Varo, Raquel, Davila, Jose C, Vizuete, Marisa, Gutierrez, Antonia, Vitorica, Javier

“…Microglial activation has been considered a crucial player in the pathological process of multiple human neurodegenerative diseases. In some of these…”
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Detection of Drug-Resistant Tuberculosis by Xpert MTB/RIF in Swaziland by Sanchez-Padilla, Elisabeth, Merker, Matthias, Beckert, Patrick, Jochims, Frauke, Dlamini, Themba, Kahn, Patricia, Bonnet, Maryline, Niemann, Stefan

“…Rapid diagnosis of drug-resistant tuberculosis is important in determining proper management. This letter reports on limitations of the Xpert MTB/RIF assay in…”
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Predictive performance of interferon-gamma release assays and the tuberculin skin test for incident tuberculosis: an individual participant data meta-analysis by Hamada, Yohhei, Gupta, Rishi K., Quartagno, Matteo, Izzard, Abbie, Acuna-Villaorduna, Carlos, Altet, Neus, Diel, Roland, Dominguez, Jose, Floyd, Sian, Gupta, Amita, Huerga, Helena, Jones-López, Edward C., Kinikar, Aarti, Lange, Christoph, van Leth, Frank, Liu, Qiao, Lu, Wei, Lu, Peng, Rueda, Irene Latorre, Martinez, Leonardo, Mbandi, Stanley Kimbung, Muñoz, Laura, Padilla, Elisabeth Sánchez, Paradkar, Mandar, Scriba, Thomas, Sester, Martina, Shanaube, Kwame, Sharma, Surendra K., Sloot, Rosa, Sotgiu, Giovanni, Thiruvengadam, Kannan, Vashishtha, Richa, Abubakar, Ibrahim, Rangaka, Molebogeng X.

“…Evidence on the comparative performance of purified protein derivative tuberculin skin tests (TST) and interferon-gamma release assays (IGRA) for predicting…”
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Smoking exacerbates amyloid pathology in a mouse model of Alzheimer’s disease by Moreno-Gonzalez, Ines, Estrada, Lisbell D., Sanchez-Mejias, Elisabeth, Soto, Claudio

“…Several epidemiological studies have shown that cigarette smoking might alter the incidence of Alzheimer’s disease. However, inconsistent results have been…”
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Transgenic Mouse Models of Alzheimer's Disease: An Integrative Analysis by Sanchez-Varo, Raquel, Mejias-Ortega, Marina, Fernandez-Valenzuela, Juan Jose, Nuñez-Diaz, Cristina, Caceres-Palomo, Laura, Vegas-Gomez, Laura, Sanchez-Mejias, Elisabeth, Trujillo-Estrada, Laura, Garcia-Leon, Juan Antonio, Moreno-Gonzalez, Ines, Vizuete, Marisa, Vitorica, Javier, Baglietto-Vargas, David, Gutierrez, Antonia

“…Alzheimer's disease (AD) constitutes the most prominent form of dementia among elderly individuals worldwide. Disease modeling using murine transgenic mice was…”
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Polycystic echinococcosis in Pacas, Amazon region, Peru by Mayor, Pedro, Baquedano, Laura E, Sanchez, Elisabeth, Aramburu, Javier, Gomez-Puerta, Luis A, Mamani, Victor J, Gavidia, Cesar M

“…In the Peruvian Amazon, paca meat is consumed by humans. To determine human risk for polycystic echinococcosis, we examined wild pacas from 2 villages; 15…”
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