Search Results - "Sánchez, Belén G"

Capsaicin Targets Lipogenesis in HepG2 Cells Through AMPK Activation, AKT Inhibition and PPARs Regulation by Bort, Alicia, Sánchez, Belén G, Mateos-Gómez, Pedro A, Díaz-Laviada, Inés, Rodríguez-Henche, Nieves

“…Obesity, a major risk factor for chronic diseases such as type 2 diabetes (T2D), represents a serious primary health problem worldwide. Dietary habits are of…”
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Alteration of the HIF-1α/VEGF Signaling Pathway and Disruption of the Cell Cycle by Second Generation Carbosilan Dendrimers by Barrios, Oscar, Sánchez, Belén G., Rodríguez-Prieto, Tamara, Cano, Jesús, Bort, Alicia, Gómez, Rafael, Díaz-Laviada, Inés

“…Current therapies against prostate cancer (PCa) disease, such as surgery, radiotherapy, or in last term chemical castration by androgen deprivation, have led…”
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Combination of the natural product capsaicin and docetaxel synergistically kills human prostate cancer cells through the metabolic regulator AMP-activated kinase by Sánchez, Belén G, Bort, Alicia, Mateos-Gómez, Pedro A, Rodríguez-Henche, Nieves, Díaz-Laviada, Inés

“…Current chemotherapy for castration-resistant prostate cancer is established on taxane-based compounds like docetaxel. However, eventually, the development of…”
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The red pepper's spicy ingredient capsaicin activates AMPK in HepG2 cells through CaMKKβ by Bort, Alicia, Sánchez, Belén G, Spínola, Elena, Mateos-Gómez, Pedro A, Rodríguez-Henche, Nieves, Díaz-Laviada, Inés

“…Capsaicin is a natural compound present in chili and red peppers and the responsible of their spicy flavor. It has recently provoked interest because of its…”
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Resistance to 2-Hydroxy-Flutamide in Prostate Cancer Cells Is Associated with the Downregulation of Phosphatidylcholine Biosynthesis and Epigenetic Modifications by Mora-Rodríguez, José María, Sánchez, Belén G, Sebastián-Martín, Alba, Díaz-Yuste, Alba, Sánchez-Chapado, Manuel, Palacín, Ana María, Sánchez-Rodríguez, Carlos, Bort, Alicia, Díaz-Laviada, Inés

“…In this study, we examined the metabolic adaptations of a chemoresistant prostate cancer cell line in comparison to a sensitive cell line. We utilized prostate…”
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Diabetic individuals with COVID-19 exhibit reduced efficacy of gliptins in inhibiting dipeptidyl peptidase 4 (DPP4). A suggested explanation for increased COVID-19 susceptibility in patients with type 2 diabetes mellitus (T2DM) by Mora-Rodríguez, José María, Sánchez, Belén G, Bort, Alicia, Díaz-Yuste, Alba, Ballester-González, Rubén, Arrieta, Francisco, Sebastián-Martín, Alba, Díaz-Laviada, Inés

“…Dipeptidyl peptidase 4 (DPP4) has been proposed as a coreceptor for SARS-CoV-2 cellular entry. Considering that type 2 diabetes mellitus (T2DM) has been…”
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Targeting AMP‐activated kinase impacts hepatocellular cancer stem cells induced by long‐term treatment with sorafenib by Bort, Alicia, Sánchez, Belén G., Mateos‐Gómez, Pedro A., Vara‐Ciruelos, Diana, Rodríguez‐Henche, Nieves, Díaz‐Laviada, Inés

“…Hepatocellular carcinoma (HCC) is the third leading cause of cancer death worldwide. HCC treatment is hindered by the frequent emergence of chemoresistance to…”
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The Natural Chemotherapeutic Capsaicin Activates AMPK through LKB1 Kinase and TRPV1 Receptors in Prostate Cancer Cells by Sánchez, Belén G, Bort, Alicia, Mora-Rodríguez, José M, Díaz-Laviada, Inés

“…The natural bioactive compound capsaicin has been reported to have anticancer activity, although the underlying mechanism of action has not been completely…”
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Role of Dipeptidyl Peptidase-4 (DPP4) on COVID-19 Physiopathology by Sebastián-Martín, Alba, Sánchez, Belén G, Mora-Rodríguez, José M, Bort, Alicia, Díaz-Laviada, Inés

“…DPP4/CD26 is a single-pass transmembrane protein with multiple functions on glycemic control, cell migration and proliferation, and the immune system, among…”
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Metabolic fingerprinting of chemotherapy-resistant prostate cancer stem cells. An untargeted metabolomic approach by liquid chromatography-mass spectrometry by Bort, Alicia, G. Sánchez, Belén, León, Carlos, Nozal, Leonor, Mora-Rodríguez, José M., Castro, Florentina, Crego, Antonio L., Díaz-Laviada, Inés

“…Chemoresistance is one of the most important challenges in cancer therapy. The presence of cancer stem cells within the tumor may contribute to chemotherapy…”
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A Highly Sensitive Immunoassay for Determination of Immune Response to SARS-CoV-2 in Capillary Blood Samples by Sánchez, Belén G, Bort, Alicia, Mora-Rodríguez, José María, Díaz-Yuste, Alba, Gasalla, José Manuel, Sánchez-Chapado, Manuel, Sebastián-Martín, Alba, Díaz-Laviada, Inés

“…Throughout the pandemic, serological assays have been revealed as crucial for detecting previous exposures to the virus and determining the timing of antibody…”
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Increase in Ischemia-Modified Albumin and Pregnancy-Associated Plasma Protein-A in COVID-19 Patients by Sanchez, Belén G., Gasalla, Jose M., Sánchez-Chapado, Manuel, Bort, Alicia, Diaz-Laviada, Inés

“…This study was undertaken due to the urgent need to explore reliable biomarkers for early SARS-CoV-2 infection. We performed a retrospective study analyzing…”
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Androgen Deprivation Induces Reprogramming of Prostate Cancer Cells to Stem-Like Cells by Sánchez, Belén G, Bort, Alicia, Vara-Ciruelos, Diana, Díaz-Laviada, Inés

“…In the past few years, cell plasticity has emerged as a mode of targeted therapy evasion in prostate adenocarcinoma. When exposed to anticancer therapies,…”
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Dysregulated lipid metabolism in hepatocellular carcinoma cancer stem cells by Bort, Alicia, Sánchez, Belén G., de Miguel, Irene, Mateos-Gómez, Pedro A., Diaz-Laviada, Inés

“…According to the stem cell theory for cancer, hepatocellular carcinomas are sustained by a group of cancer stem cells (CSCs) which are responsible for…”
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The red pepper's spicy ingredient capsaicin activates AMPK in HepG2 cells through CaMKK[beta] by Bort, Alicia, Sánchez, Belén G, Spínola, Elena, Mateos-Gómez, Pedro A, Rodríguez-Henche, Nieves, Díaz-Laviada, Inés

“…Capsaicin is a natural compound present in chili and red peppers and the responsible of their spicy flavor. It has recently provoked interest because of its…”
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Electroacupuncture and Curcumin Promote Oxidative Balance and Motor Function Recovery in Rats Following Traumatic Spinal Cord Injury by Alvarado-Sanchez, Belen G., Salgado-Ceballos, Hermelinda, Torres-Castillo, Sergio, Rodriguez-Silverio, Juan, Lopez-Hernandez, Monica E., Quiroz-Gonzalez, Salvador, Sanchez-Torres, Stephanie, Mondragón-Lozano, Rodrigo, Fabela-Sanchez, Omar

“…Spinal cord injury (SCI) is a condition that puts the patient’s life at risk in the acute phase and, during the chronic stage, results in permanent deficits in…”
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