Search Results - "Sáez, T."

Extracellular ATP and adenosine: The Yin and Yang in immune responses? by Faas, M M, Sáez, T, de Vos, P

“…Extracellular adenosine 5'-triphosphate (ATP) and adenosine molecules are intimately involved in immune responses. ATP is mostly a pro-inflammatory molecule…”
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Human supraphysiological gestational weight gain and fetoplacental vascular dysfunction by Pardo, F, Silva, L, Sáez, T, Salsoso, R, Gutiérrez, J, Sanhueza, C, Leiva, A, Sobrevia, L

“…Objective: Human foetal development and growth in an environment of maternal obesity associates with high risk of cardiovascular disease and adverse neonatal…”
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DNA Injury and Repair Systems by Sáez, Guillermo T

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Insulin receptor isoforms: an integrated view focused on gestational diabetes mellitus by Westermeier, F., Sáez, T., Arroyo, P., Toledo, F., Gutiérrez, J., Sanhueza, C., Pardo, F., Leiva, A., Sobrevia, L.

“…Summary The human insulin receptor (IR) exists in two isoforms that differ by the absence (IR‐A) or the presence (IR‐B) of a 12‐amino acid segment encoded by…”
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Cross-sectional and longitudinal lipid determination studies in pregnant women reveal an association between increased maternal LDL cholesterol concentrations and reduced human umbilical vein relaxation by Leiva, A, Salsoso, R, Sáez, T, Sanhueza, C, Pardo, F, Sobrevia, L

“…Abstract Introduction Maternal hypercholesterolemia and hypertriglyceridemia during pregnancy is correlated with fetoplacental endothelial dysfunction and…”
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The Mediterranean diet improves the systemic lipid and DNA oxidative damage in metabolic syndrome individuals. A randomized, controlled, trial by Mitjavila, Maria Teresa, Fandos, Marta, Salas-Salvadó, Jordi, Covas, María-Isabel, Borrego, Silvia, Estruch, Ramón, Lamuela-Raventós, Rosa, Corella, Dolores, Martínez-Gonzalez, Miguel Ángel, Sánchez, Julia M, Bulló, Mónica, Fitó, Montserrat, Tormos, Carmen, Cerdá, Concha, Casillas, Rosario, Moreno, Juan José, Iradi, Antonio, Zaragoza, Cristóbal, Chaves, Javier, Sáez, Guillermo T

“…Summary Background & aims Metabolic syndrome (MetS), in which a non-classic feature is an increase in systemic oxidative biomarkers, presents a high risk of…”
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Effect of olive oil phenolic compounds on the expression of blood pressure-related genes in healthy individuals by Martín-Peláez, Sandra, Castañer, Olga, Konstantinidou, Valentini, Subirana, Isaac, Muñoz-Aguayo, Daniel, Blanchart, Gemma, Gaixas, Sonia, de la Torre, Rafael, Farré, Magí, Sáez, Guillermo T, Nyyssönen, Kristina, Zunft, Hans Joachim, Covas, Maria Isabel, Fitó, Montse

“…Purpose To investigate whether the ingestion of olive oil having different phenolic contents influences the expression of blood pressure-related genes,…”
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Pterostilbene Decreases the Antioxidant Defenses of Aggressive Cancer Cells In Vivo: A Physiological Glucocorticoids- and Nrf2-Dependent Mechanism by Benlloch, María, Obrador, Elena, Valles, Soraya L, Rodriguez, María L, Sirerol, J Antoni, Alcácer, Javier, Pellicer, José A, Salvador, Rosario, Cerdá, Concha, Sáez, Guillermo T, Estrela, José M

“…Polyphenolic phytochemicals have anticancer properties. However, in mechanistic studies, lack of correlation with the bioavailable concentrations is a critical…”
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One-year follow-up of clinical, metabolic and oxidative stress profile of morbid obese patients after laparoscopic sleeve gastrectomy. 8-oxo-dG as a clinical marker by Monzo-Beltran, Lidia, Vazquez-Tarragón, Antonio, Cerdà, Concha, Garcia-Perez, Paula, Iradi, Antonio, Sánchez, Carlos, Climent, Benjamin, Tormos, Carmen, Vázquez-Prado, Antonio, Girbés, Javier, Estáñ, Nuria, Blesa, Sebastián, Cortés, Raquel, Chaves, Felipe J, Sáez, Guillermo T

“…Obesity has grown worldwide over the last few decades. In its different degrees, obesity is accompanied by many clinical and biochemical alterations reflecting…”
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Insulin restores l -arginine transport requiring adenosine receptors activation in umbilical vein endothelium from late-onset preeclampsia by Salsoso, R, Guzmán-Gutiérrez, E, Sáez, T, Bugueño, K, Ramírez, M.A, Farías, M, Pardo, F, Leiva, A, Sanhueza, C, Mate, A, Vázquez, C, Sobrevia, L

“…Abstract Introduction Preeclampsia is associated with impaired placental vasodilation and reduced endothelial nitric oxide synthase (eNOS) activity in the…”
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Role of equilibrative adenosine transporters and adenosine receptors as modulators of the human placental endothelium in gestational diabetes mellitus by Pardo, F, Arroyo, P, Salomón, C, Westermeier, F, Salsoso, R, Sáez, T, Guzmán-Gutiérrez, E, Leiva, A, Sobrevia, L

“…Abstract Gestational diabetes mellitus (GDM) is a diseases that alters human placenta macro and microvascular reactivity as a result of endothelial…”
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Oxidative stress in bisphosphonate-related osteonecrosis of the jaws by Bagan, Jose, Sáez, Guillermo T., Tormos, M. Carmen, Gavalda-Esteve, Carmen, Bagan, Leticia, Leopoldo-Rodado, Manuel, Calvo, Javier, Camps, Carlos

“…Objectives To analyze whether oxidative stress (OS) changes are present in patients with bisphosphonate‐related osteonecrosis of the jaw (BRONJ) versus…”
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Interleukin-6 concentration changes in plasma and saliva in bisphosphonate-related osteonecrosis of the jaws by Bagan, J, Sáez, GT, Tormos, MC, Hens, E, Terol, MJ, Bagan, L, Diaz-Fernández, JM, Lluch, A, Camps, C

“…Aim To determine the plasma and saliva levels of IL‐6 in patients with bisphosphonate‐related osteonecrosis of the jaws (BRONJ) and to investigate whether…”
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Long-Term Effects of Microfiltered Seawater and Resistance Training with Elastic Bands on Hepatic Parameters, Inflammation, Oxidative Stress, and Blood Pressure of Older Women: A 32-Week, Double-Blinded, Randomized, Placebo-Controlled Trial by Babiloni-Lopez, Carlos, Gargallo, Pedro, Juesas, Alvaro, Gene-Morales, Javier, Saez-Berlanga, Angel, Jiménez-Martínez, Pablo, Casaña, Jose, Benitez-Martinez, Josep C, Sáez, Guillermo T, Fernández-Garrido, Julio, Alix-Fages, Carlos, Colado, Juan C

“…The bulk of research on microfiltered seawater (SW) is based on its short-term effects. However, the long-term physiological adaptations to combining SW and…”
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Early ROS-mediated DNA damage and oxidative stress biomarkers in Monoclonal B Lymphocytosis by Collado, Rosa, Oliver, Isabel, Tormos, Carmen, Egea, Mercedes, Miguel, Amparo, Cerdá, Concha, Ivars, David, Borrego, Silvia, Carbonell, Felix, Sáez, Guillermo T

“…Abstract Monoclonal B Lymphocytosis (MBL) is defined as asymptomatic monoclonal B-cell expansion characterised by a CLL-phenotype, but with less than 5 × 109…”
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Frying oils with high natural or added antioxidants content, which protect against postprandial oxidative stress, also protect against DNA oxidation damage by Rangel-Zuñiga, Oriol A., Haro, Carmen, Tormos, Carmen, Perez-Martinez, Pablo, Delgado-Lista, Javier, Marin, Carmen, Quintana-Navarro, Gracia M., Cerdá, Concha, Sáez, Guillermo T., Lopez-Segura, Fernando, Lopez-Miranda, Jose, Perez-Jimenez, Francisco, Camargo, Antonio

“…Purpose Using sunflower oil as frying oil increases postprandial oxidative stress, which is considered the main endogenous source of DNA oxidative damage. We…”
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Oxidative imbalance in low/intermediate-1-risk myelodysplastic syndrome patients: The influence of iron overload by Ivars, David, Orero, María Teresa, Javier, Karla, Díaz-Vico, Laura, García-Giménez, José Luis, Mena, Salvador, Tormos, Carmen, Egea, Mercedes, Pérez, Pedro Luis, Arrizabalaga, Beatriz, Ruiz, María Ángeles, Yagüe, Nuria, Tormo, Mar, Sancho-Tello, Reyes, Gomes, Angela, Algueró, Carmen, O'Connor, José Enrique, Sáez, Guillermo T., Carbonell, Félix, Collado, Rosa

“…To assess the generation of reactive oxygen species (ROS) and the involvement of the main antioxidant pathways in low/intermediate-1-risk myelodysplastic…”
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The Effect of Moderate- Versus High-Intensity Resistance Training on Systemic Redox State and DNA Damage in Healthy Older Women by Gargallo, Pedro, Colado, Juan C., Juesas, Alavaro, Hernando-Espinilla, Amaya, Estañ-Capell, Nuria, Monzó-Beltran, Lidia, García-Pérez, Paula, Cauli, Omar, Sáez, Guillermo T.

“…This study investigated effects of a 16-week progressive resistance training program (RTP) with elastic bands at two different intensities on systemic redox…”
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Oxidative stress is associated with an increased antioxidant defense in elderly subjects: a multilevel approach by Flores-Mateo, Gemma, Elosua, Roberto, Rodriguez-Blanco, Teresa, Basora-Gallisà, Josep, Bulló, Mònica, Salas-Salvadó, Jordi, Martínez-González, Miguel Ángel, Estruch, Ramon, Corella, Dolores, Fitó, Montserrat, Fiol, Miquel, Arós, Fernando, Gómez-Gracia, Enrique, Subirana, Isaac, Lapetra, José, Ruiz-Gutiérrez, Valentina, Sáez, Guillermo T, Covas, Maria-Isabel

“…Studies of associations between plasma GSH-Px activity and cardiovascular risk factors have been done in humans, and contradictory results have been reported…”
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Virgin olive oil enriched with its own phenolic compounds or complemented with thyme improves endothelial function: The potential role of plasmatic fat-soluble vitamins. A double blind, randomized, controlled, cross-over clinical trial by Valls, Rosa-M., Farràs, Marta, Pedret, Anna, Fernández-Castillejo, Sara, Catalán, Úrsula, Romeu, Marta, Giralt, Montse, Sáez, Guillermo-T., Fitó, Montserrat, de la Torre, Rafael, Covas, María-Isabel, Motilva, María-José, Solà, Rosa, Rubió, Laura

“…The aim of the present study was to assess whether different functional virgin olive oils (FVOOs) with varying phenolic compounds (PC) could protect the…”
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