Search Results - "Sádaba, B"
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A phase I clinical trial of thymidine kinase-based gene therapy in advanced hepatocellular carcinoma
Published in Cancer gene therapy (01-12-2010)“…The aim of this phase I clinical trial was to assess the feasibility and safety of intratumoral administration of a first-generation adenoviral vector encoding…”
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2
Monoclonal antibodies: Pharmacokinetics as a basis for new dosage regimens?
Published in Journal of Oncology Pharmacy Practice (01-10-2015)“…Complete monoclonal IgG antibodies which are in use in clinical practice share some pharmacological properties resulting in high concentrations in plasma. This…”
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Book Review Journal Article -
3
Oral Availability of Bilastine
Published in Clinical drug investigation (01-05-2013)“…Background and Objective Bilastine (Bilaxten™) is a novel non-sedating H 1 receptor antagonist (antihistamine) developed in the dosage form of oral tablets and…”
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4
Clinical relevance of sirolimus drug interactions in transplant patients
Published in Transplantation proceedings (01-12-2004)“…Sirolimus, a new immunosuppressant drug; is metabolized by cytochrome P450 3A4 (CYP3A4) and is a substrate of the P-glycoprotein drug efflux pump. The…”
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Monte Carlo simulation describing the pharmacodynamic profile of cefditoren in plasma from healthy volunteers
Published in International journal of antimicrobial agents (01-04-2008)Get full text
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6
Aflibercept. Una aproximación a la farmacología
Published in Archivos de la Sociedad Española de Oftalmología (01-03-2015)“…Resumen Aflibercept es una proteina de fusion que combina en su estructura quimica, la fraccion constante de cualquier IgG con una fraccion variable construida…”
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7
Relationship between pharmacokinetics and pharmacodynamics of β‐lactams and outcome
Published in Clinical microbiology and infection (01-11-2004)“…The in‐vitro susceptibility of an organism and the pharmacokinetics of an antimicrobial agent are two basic factors on which the choice of standardised…”
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Diversity and Screening of Cellulolytic Microorganisms from Mangrove Forests, Natural Parks, Paddy Field, and Sugarcane Plantation in Panay Island, Philippines
Published in International journal of microbiology (2024)“…Cellulolytic microorganisms secrete cellulase, which plays a crucial role in the conversion of lignocellulosic biomass into value-added products with diverse…”
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9
Fungal diversity of mangrove-associated sponges from New Washington, Aklan, Philippines
Published in Mycology (02-01-2019)“…Sponge-associated fungi are the least explored marine fungal groups. It is only in recent years that fungal symbionts of marine sponges have received attention…”
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10
Concurrent clarithromycin and cyclosporin A treatment
Published in Journal of antimicrobial chemotherapy (01-09-1998)“…Although macrolides have been associated with significant pharmacokinetic interactions, clarithromycin is considered to have a low interaction capacity. In…”
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Rapid high-performance liquid chromatographic determination of cefepime in human plasma
Published in Biomedical chromatography (01-06-1999)“…A simple, rapid and reproducible high‐performance liquid chromatographic method for the quantitative determination of cefepime in human plasma was developed…”
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12
Oral versus intravenous therapy in the treatment of systemic mycosis
Published in Clinical microbiology and infection (01-03-2004)“…The great majority of systemic fungal infections require long-term therapy that often extends 6–12 months, particularly in immunosuppressed patients. It can be…”
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13
Development of a chromatographic method for the determination of saquinavir in plasma samples of HIV patients
Published in Biomedical chromatography (01-02-2002)“…A simple, sensitive and reproducible high‐performance liquid chromatographic method for detecting and quantifying saquinavir in human plasma is described…”
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14
Pharmacokinetics of tramadol enantiomers and their respective phase I metabolites in relation to CYP2D6 phenotype
Published in Pharmacological research (01-02-2007)“…Our objective was to evaluate the effect of CYP2D6 phenotype in the enantioselective metabolism of tramadol in Spanish healthy human volunteers. A single oral…”
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Bioavailability of two oral fentanyl transmucosal formulations in healthy volunteers: and open-label, crossover, randomised study
Published in Revista de la Sociedad Española del Dolor (2018)“…ABSTRACT Introduction: Oral transmucosal fentanyl citrate (OTFC) was the first product specifically designed for the treatment of breakthrough pain. It is…”
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Determination of ketorolac enantiomers in plasma using enantioselective liquid chromatography. Application to pharmacokinetic studies
Published in Chromatographia (01-08-1998)Get full text
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Rapid determination of ranitidine in human plasma by high-performance liquid chromatography
Published in Chromatographia (01-04-1998)Get full text
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18
Simultaneous stereoselective analysis of tramadol and its primary phase I metabolites in plasma by liquid chromatography: Application to a pharmacokinetic study in humans
Published in Journal of Chromatography A (26-03-2004)“…This paper describes a bioanalytical method involving a simple liquid–liquid extraction for the simultaneous HPLC determination of the enantiomers of tramadol,…”
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Journal Article Conference Proceeding -
19
Detection and incidence of drug-induced agranulocytosis in hospital : a prospective analysis from laboratory signals
Published in European journal of clinical pharmacology (01-03-2007)“…Our objectives were to assess the detection and incidence of drug-induced agranulocytosis in two university hospitals using hematology laboratory data. A…”
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Journal Article -
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Aflibercept. An approach to pharmacology
Published in Archivos de la Sociedad Española de Oftalmología (01-03-2015)“…Aflibercept is a fusion protein whose chemical structure combines the constant fraction of any IgG with a variable fraction constructed with fundamental parts…”
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