Search Results - "Rzeszotarski, W. Janusz"
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Affinity and selectivity of the optical isomers of 3-quinuclidinyl benzilate and related muscarinic antagonists
Published in Journal of medicinal chemistry (01-07-1988)“…All of the optical isomers of the muscarinic antagonists 3-(1-azabicyclo[2.2.2]octyl) alpha-hydroxy-alpha,alpha-diphenylacetate (3-quinuclidinyl benzilate,…”
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Analogs of oxybutynin. Synthesis and antimuscarinic and bladder activity of some substituted 7-amino-1-hydroxy-5-heptyn-2-ones and related compounds
Published in Journal of medicinal chemistry (01-10-1991)“…Oxybutynin chloride [4-(diethylamino)-2-butynyl alpha-cyclohexyl-alpha-hydroxybenzeneacetate hydrochloride, Ditropan] is widely used for the relief of symptoms…”
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Aminoalkynyldithianes. A new class of calcium channel blockers
Published in Journal of medicinal chemistry (01-05-1991)“…Several dithiane derivatives, prepared as intermediates for compounds structurally related to the therapeutically useful antimuscarinic agent oxybutynin, were…”
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Synthesis of some 3-(1-azabicyclo[2.2.2]octyl) 3-amino-2-hydroxy-2-phenylpropionates: profile of antimuscarinic efficacy and selectivity
Published in Journal of medicinal chemistry (01-01-1990)“…A series of 3-quinuclidinyl atrolactate [3-(1-azabicyclo[2.2.2]octyl) 2-hydroxy-2-phenylpropionate, QNA] derivatives in which the methyl group of the parent is…”
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