Search Results - "Ryu, Yuhee"

Gallic Acid Reduces Blood Pressure and Attenuates Oxidative Stress and Cardiac Hypertrophy in Spontaneously Hypertensive Rats by Jin, Li, Piao, Zhe Hao, Sun, Simei, Liu, Bin, Kim, Gwi Ran, Seok, Young Mi, Lin, Ming Quan, Ryu, Yuhee, Choi, Sin Young, Kee, Hae Jin, Jeong, Myung Ho

“…Gallic acid (GA) has been reported to have beneficial effects on cancer, vascular calcification, and diabetes-induced myocardial dysfunction. We hypothesized…”
Get full text

Class I histone deacetylase inhibitor MS-275 attenuates vasoconstriction and inflammation in angiotensin II-induced hypertension by Ryu, Yuhee, Kee, Hae Jin, Sun, Simei, Seok, Young Mi, Choi, Sin Young, Kim, Gwi Ran, Kee, Seung-Jung, Pflieger, Marc, Kurz, Thomas, Kim, Hyung-Seok, Jeong, Myung Ho

“…Non-selective histone deacetylase (HDAC) inhibitors are known to improve hypertension. Here, we investigated the therapeutic effect and regulatory mechanism of…”
Get full text

Piceatannol Attenuates Renal Fibrosis Induced by Unilateral Ureteral Obstruction via Downregulation of Histone Deacetylase 4/5 or p38-MAPK Signaling by Choi, Sin Young, Piao, Zhe Hao, Jin, Li, Kim, Jung Ha, Kim, Gwi Ran, Ryu, Yuhee, Lin, Ming Quan, Kim, Hyung-Seok, Kee, Hae Jin, Jeong, Myung Ho

“…Piceatannol, a resveratrol metabolite, is a phenolic compound found in red wine and grapes. We investigated the effect of piceatannol on renal fibrosis and…”
Get full text

Gentisic acid prevents the transition from pressure overload-induced cardiac hypertrophy to heart failure by Sun, Simei, Kee, Hae Jin, Ryu, Yuhee, Choi, Sin Young, Kim, Gwi Ran, Kim, Hyung-Seok, Kee, Seung-Jung, Jeong, Myung Ho

“…We previously reported that gentisic acid attenuates cardiac hypertrophy and fibrosis in transverse aortic constriction (TAC)-induced cardiac hypertrophy…”
Get full text

Selective inhibition of histone deacetylase 8 improves vascular hypertrophy, relaxation, and inflammation in angiotensin II hypertensive mice by Kee, Hae Jin, Ryu, Yuhee, Seok, Young Mi, Choi, Sin Young, Sun, Simei, Kim, Gwi Ran, Jeong, Myung Ho

“…The dysregulation of histone deacetylase (HDAC) protein expression or its enzyme activity is implicated in a variety of diseases. Cardiac HDAC6 and HDAC8…”
Get full text

Gallic acid prevents isoproterenol-induced cardiac hypertrophy and fibrosis through regulation of JNK2 signaling and Smad3 binding activity by Ryu, Yuhee, Jin, Li, Kee, Hae Jin, Piao, Zhe Hao, Cho, Jae Yeong, Kim, Gwi Ran, Choi, Sin Young, Lin, Ming Quan, Jeong, Myung Ho

“…Gallic acid, a type of phenolic acid, has been shown to have beneficial effects in inflammation, vascular calcification, and metabolic diseases. The present…”
Get full text

Gallic acid attenuates hypertension, cardiac remodeling, and fibrosis in mice with N G-nitro-L-arginine methyl ester-induced hypertension via regulation of histone deacetylase 1 or histone deacetylase 2 by Jin, Li, Lin, Ming Quan, Piao, Zhe Hao, Cho, Jae Yeong, Kim, Gwi Ran, Choi, Sin Young, Ryu, Yuhee, Sun, Simei, Kee, Hae Jin, Jeong, Myung Ho

Get full text

Inhibition of class IIa histone deacetylase activity by gallic acid, sulforaphane, TMP269, and panobinostat by Choi, Sin Young, Kee, Hae Jin, Jin, Li, Ryu, Yuhee, Sun, Simei, Kim, Gwi Ran, Jeong, Myung Ho

“…Histone deacetylase (HDAC) inhibitors are gaining increasing attention as potential therapeutics for cardiovascular diseases as well as cancer. We recently…”
Get full text

Gentisic acid attenuates pressure overload‐induced cardiac hypertrophy and fibrosis in mice through inhibition of the ERK1/2 pathway by Sun, Simei, Kee, Hae Jin, Jin, Li, Ryu, Yuhee, Choi, Sin Young, Kim, Gwi Ran, Jeong, Myung Ho

“…We previously reported that gentisic acid (2,5‐dihydroxybenzoic acid) is the third most abundant phenolic component of Dendropanax morbifera branch extracts…”
Get full text

Gallic acid improves cardiac dysfunction and fibrosis in pressure overload-induced heart failure by Jin, Li, Sun, Simei, Ryu, Yuhee, Piao, Zhe Hao, Liu, Bin, Choi, Sin Young, Kim, Gwi Ran, Kim, Hyung-Seok, Kee, Hae Jin, Jeong, Myung Ho

“…Gallic acid is a trihydroxybenzoic acid found in tea leaves and some plants. Here, we report the effect of gallic acid on cardiac dysfunction and fibrosis in a…”
Get full text

Histone deacetylase and GATA-binding factor 6 regulate arterial remodeling in angiotensin II-induced hypertension by Kim, Gwi Ran, Cho, Soo-Na, Kim, Hyung-Seok, Yu, Seon Young, Choi, Sin Young, Ryu, Yuhee, Lin, Ming Quan, Jin, Li, Kee, Hae Jin, Jeong, Myung Ho

“…OBJECTIVE:Histone deacetylase (HDAC) inhibitors have been reported to improve essential and secondary hypertension. However, the specific HDAC that might serve…”
Get full text

Tubastatin A suppresses renal fibrosis via regulation of epigenetic histone modification and Smad3-dependent fibrotic genes by Choi, Sin Young, Ryu, Yuhee, Kee, Hae Jin, Cho, Soo-Na, Kim, Gwi Ran, Cho, Jae Yeong, Kim, Hyung-Seok, Kim, In-Kyeom, Jeong, Myung Ho

“…Abstract Inflammation and fibrosis are implicated in the pathogenesis of hypertensive kidney damage. We previously demonstrated that a nonspecific histone…”
Get full text

Gallic acid attenuates calcium calmodulin‐dependent kinase II‐induced apoptosis in spontaneously hypertensive rats by Jin, Li, Piao, Zhe Hao, Liu, Chun Ping, Sun, Simei, Liu, Bin, Kim, Gwi Ran, Choi, Sin Young, Ryu, Yuhee, Kee, Hae Jin, Jeong, Myung Ho

“…Hypertension causes cardiac hypertrophy and leads to heart failure. Apoptotic cells are common in hypertensive hearts. Ca2+/calmodulin‐dependent protein kinase…”
Get full text

Histone deacetylase inhibitor LMK235 attenuates vascular constriction and aortic remodelling in hypertension by Choi, Sin Young, Kee, Hae Jin, Sun, Simei, Seok, Young Mi, Ryu, Yuhee, Kim, Gwi Ran, Kee, Seung‐Jung, Pflieger, Marc, Kurz, Thomas, Kassack, Matthias U., Jeong, Myung Ho

“…Here, we report that LMK235, a class I and histone deacetylase (HDAC6)‐preferential HDAC inhibitor, reduces hypertension via inhibition of vascular contraction…”
Get full text

Class I HDACs specifically regulate E‐cadherin expression in human renal epithelial cells by Choi, Sin Y., Kee, Hae J., Kurz, Thomas, Hansen, Finn K., Ryu, Yuhee, Kim, Gwi R., Lin, Ming Q., Jin, Li, Piao, Zhe H., Jeong, Myung H.

“…Epithelial‐mesenchymal transition (EMT) and renal fibrosis are closely involved in chronic kidney disease. Inhibition of histone deacetylase (HDAC) has an…”
Get full text

Gallic acid attenuates pulmonary fibrosis in a mouse model of transverse aortic contraction-induced heart failure by Jin, Li, Piao, Zhe Hao, Sun, Simei, Liu, Bin, Ryu, Yuhee, Choi, Sin Young, Kim, Gwi Ran, Kim, Hyung-Seok, Kee, Hae Jin, Jeong, Myung Ho

“…Gallic acid, a trihydroxybenzoic acid found in tea and other plants, attenuates cardiac hypertrophy, fibrosis, and hypertension in animal models. However, the…”
Get full text

Gallic acid inhibits vascular calcification through the blockade of BMP2–Smad1/5/8 signaling pathway by Kee, Hae Jin, Cho, Soo-Na, Kim, Gwi Ran, Choi, Sin Young, Ryu, Yuhee, Kim, In Kyeom, Hong, Young Joon, Park, Hyung Wook, Ahn, Youngkeun, Cho, Jeong Gwan, Park, Jong Chun, Jeong, Myung Ho

“…Abstract Vascular calcification is associated with increased risk of morbidity and mortality in patients with cardiovascular diseases, chronic kidney diseases,…”
Get full text

Gallic acid attenuates hypertension, cardiac remodeling, and fibrosis in mice with NG-nitro-L-arginine methyl ester-induced hypertension via regulation of histone deacetylase 1 or histone deacetylase 2 by Jin, Li, Lin, Ming Quan, Piao, Zhe Hao, Cho, Jae Yeong, Kim, Gwi Ran, Choi, Sin Young, Ryu, Yuhee, Sun, Simei, Kee, Hae Jin, Jeong, Myung Ho

“…OBJECTIVE:Gallic acid, a natural chemical found in plants, has been reported to show antioxidant, anticancer, and anti-inflammatory effects. We investigated…”
Get full text

Gentisic acid attenuates pressure overload‐induced cardiac hypertrophy and fibrosis in mice through inhibition of the ERK 1/2 pathway by Sun, Simei, Kee, Hae Jin, Jin, Li, Ryu, Yuhee, Choi, Sin Young, Kim, Gwi Ran, Jeong, Myung Ho

“…We previously reported that gentisic acid (2,5‐dihydroxybenzoic acid) is the third most abundant phenolic component of Dendropanax morbifera branch extracts…”
Get full text

Dendropanax morbifera Prevents Cardiomyocyte Hypertrophy by Inhibiting the Sp1/GATA4 Pathway by Sun, Simei, Li, Tianyi, Jin, Li, Piao, Zhe Hao, Liu, Bin, Ryu, Yuhee, Choi, Sin Young, Kim, Gwi Ran, Jeong, Ji Eun, Wi, An Jin, Lee, Song Ju, Kee, Hae Jin, Jeong, Myung Ho

“…An extract of Dendropanax morbifera branch exerts antioxidant, anti-inflammatory, antithrombotic, and anticancer activities. The purpose of this study was to…”
Get more information