Search Results - "Ryu, Ji Kan"

Fibroblasts enable penile erection by Ryu, Ji-Kan, Koh, Gou Young

“…Perivascular fibroblasts may underlie erectile dysfunction…”
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Single-cell transcriptome analysis of cavernous tissues reveals the key roles of pericytes in diabetic erectile dysfunction by Bae, Seo-Gyeong, Yin, Guo Nan, Ock, Jiyeon, Suh, Jun-Kyu, Ryu, Ji-Kan, Park, Jihwan

“…Erectile dysfunction (ED) affects a significant proportion of men aged 40-70 and is caused by cavernous tissue dysfunction. Presently, the most common…”
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Pericyte-derived extracellular vesicle-mimetic nanovesicles ameliorate erectile dysfunction via lipocalin 2 in diabetic mice by Anita, Limanjaya, Yin, Guo Nan, Hong, Soon-Sun, Kang, Ju-Hee, Gho, Yong Song, Suh, Jun-Kyu, Ryu, Ji-Kan

“…Diabetes mellitus is one of the main causes of erectile dysfunction (ED). Men with diabetic ED do not respond well to oral phosphodiesterase-5 inhibitors owing…”
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Vasohibin-1 rescues erectile function through up-regulation of angiogenic factors in the diabetic mice by Song, Kang-Moon, Kim, Woo Jean, Choi, Min-Ji, Kwon, Ki-Dong, Limanjaya, Anita, Ghatak, Kalyan, Ock, Jiyeon, Yin, Guo Nan, Sato, Yasufumi, Hong, Soon-Sun, Ryu, Ji-Kan, Suh, Jun-Kyu

“…Neovascularization of the erectile tissue emerges as a beneficial curative approach to treat erectile dysfunction (ED). Here we for the first time report the…”
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Embryonic stem cell-derived extracellular vesicle-mimetic nanovesicles rescue erectile function by enhancing penile neurovascular regeneration in the streptozotocin-induced diabetic mouse by Kwon, Mi-Hye, Song, Kang-Moon, Limanjaya, Anita, Choi, Min-Ji, Ghatak, Kalyan, Nguyen, Nhat Minh, Ock, Jiyeon, Yin, Guo Nan, Kang, Ju-Hee, Lee, Man Ryul, Gho, Yong Song, Ryu, Ji-Kan, Suh, Jun-Kyu

“…Extracellular vesicles (EVs) have attracted particular interest in various fields of biology and medicine. However, one of the major hurdles in the clinical…”
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Melatonin and Exercise Counteract Sarcopenic Obesity through Preservation of Satellite Cell Function by Mankhong, Sakulrat, Kim, Sujin, Moon, Sohee, Lee, Jae-Seon, Cho, Eun-Jeong, Kwak, Hyo-Bum, Park, Dong-Ho, Ryu, Ji-Kan, Kang, Ju-Hee

“…Sarcopenic obesity (SO) is characterized by atrophic skeletal muscle impairment (sarcopenia) and obesity, which is associated with adverse outcomes of…”
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BMP2 restores erectile dysfunction through neurovascular regeneration and fibrosis reduction in diabetic mice by Kwon, Mi‐Hye, Rho, Beom Yong, Choi, Min‐Ji, Limanjaya, Anita, Ock, Jiyeon, Yin, Guo Nan, Jin, Suk‐Won, Suh, Jun‐Kyu, Chung, Doo Yong, Ryu, Ji‐Kan

“…Background The odds of erectile dysfunction are three times more prevalent in diabetes. Severe peripheral vascular and neural damage in diabetic patients…”
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Vactosertib, TGF-β receptor I inhibitor, augments the sensitization of the anti-cancer activity of gemcitabine in pancreatic cancer by Lee, Ji Eun, Lee, Pureunchowon, Yoon, Young-Chan, Han, Beom Seok, Ko, Soyeon, Park, Min Seok, Lee, Yun Ji, Kim, Sang Eun, Cho, Ye Jin, Lim, Joo Han, Ryu, Ji-Kan, Shim, Soyeon, Kim, Dae-Kee, Jung, Kyung Hee, Hong, Soon-Sun

“…Pancreatic ductal adenocarcinoma (PDAC) exhibits a pronounced extracellular matrix (ECM)-rich response, which is produced by an excessive amount of…”
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IGFBP5 antisense and short hairpin RNA (shRNA) constructs improve erectile function by inducing cavernosum angiogenesis in diabetic mice by Ock, Jiyeon, Suh, Jun‐Kyu, Hong, Soon‐Sun, Kang, Ju‐Hee, Yin, Guo Nan, Ryu, Ji‐Kan

“…Background The incidence of diabetic erectile dysfunction (ED) is rapidly increasing, and due to the severe angiopathy caused by diabetes, current drugs are…”
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Regenerative therapies as a potential treatment of erectile dysfunction by Chung, Doo Yong, Ryu, Ji-Kan, Yin, Guo Nan

“…Erectile dysfunction (ED) is the most common sexual dysfunction disease in adult males. ED can be caused by many factors, such as vascular disease, neuropathy,…”
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Pericyte-Derived Dickkopf2 Regenerates Damaged Penile Neurovasculature Through an Angiopoietin-1-Tie2 Pathway by Yin, Guo Nan, Jin, Hai-Rong, Choi, Min-Ji, Limanjaya, Anita, Ghatak, Kalyan, Minh, Nguyen Nhat, Ock, Jiyeon, Kwon, Mi-Hye, Song, Kang-Moon, Park, Heon Joo, Kim, Ho Min, Kwon, Young-Guen, Ryu, Ji-Kan, Suh, Jun-Kyu

“…Penile erection requires well-coordinated interactions between vascular and nervous system. Penile neurovascular dysfunction is a major cause of erectile…”
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Stromal Vascular Fraction From Adipose Tissue Forms Profound Vascular Network Through the Dynamic Reassembly of Blood Endothelial Cells by Koh, Young Jun, Koh, Bong Ihn, Kim, Honsoul, Joo, Hyung Joon, Jin, Ho Kyoung, Jeon, Jongwook, Choi, Chulhee, Lee, Dong Hun, Chung, Jin Ho, Cho, Chung-Hyun, Park, Won Seok, Ryu, Ji-Kan, Suh, Jun Kyu, Koh, Gou Young

“…OBJECTIVE—Tremendous efforts have been made to establish effective therapeutic neovascularization using adipose tissue-derived stromal vascular fraction (SVF),…”
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Selonsertib Inhibits Liver Fibrosis via Downregulation of ASK1/ MAPK Pathway of Hepatic Stellate Cells by Yoon, Young-Chan, Fang, Zhenghuan, Lee, Ji Eun, Park, Jung Hee, Ryu, Ji-Kan, Jung, Kyung Hee, Hong, Soon-Sun

“…Liver fibrosis constitutes a significant health problem worldwide due to its rapidly increasing prevalence and the absence of specific and effective…”
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Inhibition of Ninjurin 1 restores erectile function through dual angiogenic and neurotrophic effects in the diabetic mouse by Yin, Guo Nan, Choi, Min Ji, Kim, Woo Jean, Kwon, Mi-Hye, Song, Kang-Moon, Park, Jin-Mi, Das, Nando Dulal, Kwon, Ki-Dong, Batbold, Dulguun, Oh, Goo Taeg, Koh, Gou Young, Kim, Kyu-Won, Ryu, Ji-Kan, Suh, Jun-Kyu

“…Penile erection is a neurovascular phenomenon, and erectile dysfunction (ED) is caused mainly by vascular risk factors or diseases, neurologic abnormalities,…”
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Crystal structure of LRG1 and the functional significance of LRG1 glycan for LPHN2 activation by Yang, Jimin, Yin, Guo Nan, Kim, Do-Kyun, Han, Ah-reum, Lee, Dong Sun, Min, Kwang Wook, Fu, Yaoyao, Yun, Jeongwon, Suh, Jun-Kyu, Ryu, Ji-Kan, Kim, Ho Min

“…The serum glycoprotein leucine-rich ɑ-2-glycoprotein 1 (LRG1), primarily produced by hepatocytes and neutrophils, is a multifunctional protein that modulates…”
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Argonaute 2 Restores Erectile Function by Enhancing Angiogenesis and Reducing Reactive Oxygen Species Production in Streptozotocin (STZ)-Induced Type-1 Diabetic Mice by Liu, Fang-Yuan, Yin, Guo Nan, Ock, Jiyeon, Fridayana, Fitri Rahma, Niloofar, Lashkari, Huang, Yan, Vo, Minh Nhat, Suh, Jun-Kyu, Hong, Soon-Sun, Kang, Ju-Hee, Ryu, Ji-Kan

“…Severe vascular and nerve damage from diabetes is a leading cause of erectile dysfunction (ED) and poor response to oral phosphodiesterase 5 inhibitors…”
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Roles of Exosome-Like Vesicles Released from Inflammatory C2C12 Myotubes: Regulation of Myocyte Differentiation and Myokine Expression by Kim, Sujin, Lee, Min-Jae, Choi, Ji-Young, Park, Dong-Ho, Kwak, Hyo-Bum, Moon, Sohee, Koh, Je-Woo, Shin, Hun-Kyu, Ryu, Ji-Kan, Park, Chang-Shin, Park, Jai Hyung, Kang, Ju-Hee

“…Abstract Background/Aims: The complicated differentiation processes of cells in skeletal muscle against inflammation that induce muscle atrophy are not fully…”
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Latrophilin-2 is a novel receptor of LRG1 that rescues vascular and neurological abnormalities and restores diabetic erectile function by Yin, Guo Nan, Kim, Do-Kyun, Kang, Ji In, Im, Yebin, Lee, Dong Sun, Han, Ah-reum, Ock, Jiyeon, Choi, Min-Ji, Kwon, Mi-Hye, Limanjaya, Anita, Jung, Saet-Byel, Yang, Jimin, Min, Kwang Wook, Yun, Jeongwon, Koh, Yongjun, Park, Jong-Eun, Hwang, Daehee, Suh, Jun-Kyu, Ryu, Ji-Kan, Kim, Ho Min

“…Diabetes mellitus (DM) is a chronic metabolic disorder characterized by inappropriate hyperglycemia, which causes endothelial dysfunction and peripheral…”
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Intracavernous Delivery of Clonal Mesenchymal Stem Cells Restores Erectile Function in a Mouse Model of Cavernous Nerve Injury by Ryu, Ji‐Kan, Kim, Da‐Ham, Song, Kang Moon, Yi, TacGhee, Suh, Jun‐Kyu, Song, Sun U.

“…Recently, much attention has focused on stem cell therapy; bone marrow‐derived stem cells (BMSCs) are one of the most studied mesenchymal stem cells used in…”
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Efficacy of Low-Intensity Extracorporeal Shock Wave Treatment in Erectile Dysfunction Following Radical Prostatectomy: A Systematic Review and Meta-Analysis by Rho, Beom Yong, Kim, Si Hyeon, Ryu, Ji-Kan, Kang, Dong Hyuk, Kim, Jong Won, Chung, Doo Yong

“…Erectile dysfunction (ED) is a well-known complication of radical prostatectomy (RP). Oral 5-phosphodiesterase inhibitors are currently the most widely used…”
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