Search Results - "Ryu, Jae Ha"

Broussoflavonol B from Broussonetia kazinoki Siebold Exerts Anti-Pancreatic Cancer Activity through Downregulating FoxM1 by Jeong, Ji Hye, Ryu, Jae-Ha

“…Pancreatic cancer has a high mortality rate due to poor rates of early diagnosis. One tumor suppressor gene in particular, p53, is frequently mutated in…”
Get full text

Corylifol A from Psoralea corylifolia L. Enhances Myogenesis and Alleviates Muscle Atrophy by Han, Yeongeun, Lee, Hyejin, Li, Hua, Ryu, Jae-Ha

“…Inflammatory conditions caused by cancer, chronic diseases or aging can lead to skeletal muscle atrophy. We identified myogenic compounds from (PC), a…”
Get full text

Proton Implantation for Leaky-Wave Coupled Quantum Cascade Phase-Locked Laser Array by Zhang, Shuqi, Ryu, Jae Ha, Kirch, Jeremy D., Botez, Dan, Mawst, Luke J.

“…We demonstrate the effectiveness of current confinement via proton implantation for a three-element phase-locked array of ~ 5.3 μm-emitting quantum cascade…”
Get full text

Lignan from Alnus japonica Inhibits Adipocyte Differentiation via Cell Cycle and FOXO1 Regulation by Lee, Hyejin, Jeong, Ji Hye, Ryu, Jae-Ha

“…In the present study, we isolated a lignan ((-)-(2 ,3 )-1,4- -diferuloylsecoisolariciresinol, DFS) from and evaluated its antiobesity potential in vitro. We…”
Get full text

Anti-Inflammatory Compounds from Atractylodes macrocephala by Jeong, Dawoon, Dong, Guang-Zhi, Lee, Hwa Jin, Ryu, Jae-Ha

“…In relation to anti-inflammatory agents from medicinal plants, we have isolated three compounds from ; , 2-[(2 )-3,7-dimethyl-2,6-octadienyl]-6-methyl-2,…”
Get full text

ATM/CHK/p53 Pathway Dependent Chemopreventive and Therapeutic Activity on Lung Cancer by Pterostilbene by Lee, Hani, Kim, Yonghwan, Jeong, Ji Hye, Ryu, Jae-Ha, Kim, Woo-Young

“…Among the many stilbenoids found in a variety of berries, resveratrol and pterostilbene are of particular interest given their potential for use in cancer…”
Get full text

Isobavachalcone from Angelica keiskei Inhibits Adipogenesis and Prevents Lipid Accumulation by Lee, Hyejin, Li, Hua, Kweon, Minson, Choi, Youngsook, Kim, Min Jung, Ryu, Jae-Ha

“…We isolated isobavachalcone (IBC) from (AK) as an anti-obesity component. IBC dose-dependently inhibited 3T3-L1 adipocyte differentiation by down-regulating…”
Get full text

Structure–Activity Relationship of Phytoestrogen Analogs as ERα/β Agonists with Neuroprotective Activities by Cho, Hye Won, Gim, Hyo Jin, Li, Hua, Subedi, Lalita, Kim, Sun Yeou, Ryu, Jae-Ha, Jeon, Raok

“…A set of isoflavononid and flavonoid analogs was prepared and evaluated for estrogen receptor α (ERα) and ERβ transactivation and anti-neuroinflammatory…”
Get full text

Z-Ajoene Inhibits Growth of Colon Cancer by Promotion of CK1α Dependent β-Catenin Phosphorylation by Li, Hua, Jeong, Ji Hye, Kwon, Sung Won, Lee, Sang Kook, Lee, Hwa Jin, Ryu, Jae-Ha

“…Aberrant activation of a Wnt/β-catenin pathway results in nuclear accumulation of β-catenin in colon cancer. Inhibiting β-catenin is one strategy for treating…”
Get full text

Kazinol U inhibits melanogenesis through the inhibition of tyrosinase‐related proteins via AMP kinase activation by Lim, Jihyun, Nam, Sorim, Jeong, Ji Hye, Kim, Min Jung, Yang, Young, Lee, Myeong‐Sok, Lee, Hee Gu, Ryu, Jae‐Ha, Lim, Jong‐Seok

“…Background and Purpose Kazinol U is a prenylated flavan isolated from an extract of Broussonetia kazinoki Sieb (Moraceae). Kazinol U has shown cytoprotective…”
Get full text

A Chalcone from Ashitaba ( Angelica keiskei ) Stimulates Myoblast Differentiation and Inhibits Dexamethasone-Induced Muscle Atrophy by Kweon, Minson, Lee, Hyejin, Park, Cheol, Choi, Yung Hyun, Ryu, Jae-Ha

“…Ashitaba, Koidzumi (AK), as a traditional medicine in Korea, Japan, and China, has been known as an elixir of life having therapeutic potential. However, there…”
Get full text

Sesquiterpenes from Artemisia princeps regulate inflammatory responses in RAW 264.7 macrophages by Kim, Na Yeon, Kim, Sooji, Lee, Hwa Jin, Ryu, Jae-Ha

“…Four sesquiterpenoids were isolated from an ethyl acetate-soluble fraction of ethanolic extract: seco-tanapartholide B (5-epi-seco-tanapartholide A) ( ),…”
Get full text

Modulation of Inducible Nitric Oxide Synthase Expression in LPS-Stimulated BV-2 Microglia by Prenylated Chalcones from Cullen corylifolium (L.) Medik. through Inhibition of I-κBα Degradation by Kim, Do Hee, Li, Hua, Han, Yeong Eun, Jeong, Ji Hye, Lee, Hwa Jin, Ryu, Jae-Ha

“…The overproduction of nitric oxide (NO) and prostaglandin E₂ (PGE₂) by microglia may cause neurodegenerative diseases, such as Alzheimer's disease and…”
Get full text

Discovery of 5-Phenoxy-2-aminopyridine Derivatives as Potent and Selective Irreversible Inhibitors of Bruton's Tyrosine Kinase by Lee, Eun, Cho, Hyewon, Lee, Da Kyung, Ha, JuHyun, Choi, Byeong Jo, Jeong, Ji Hye, Ryu, Jae-Ha, Kang, Jong Soon, Jeon, Raok

“…As a member of the tyrosine protein kinase Tec (TEC) family, Bruton's tyrosine kinase (BTK) is considered a promising therapeutic target due to its crucial…”
Get full text

Bavachin from Psoralea corylifolia Improves Insulin-Dependent Glucose Uptake through Insulin Signaling and AMPK Activation in 3T3-L1 Adipocytes by Lee, Hyejin, Li, Hua, Noh, Minsoo, Ryu, Jae-Ha

“…The fruit of Psoralea corylifolia L. (Fabaceae) (PC), known as "Bo-Gol-Zhee" in Korea has been used as traditional medicine. Ethanol and aqueous extracts of PC…”
Get full text

Prenylated Polyphenols from Broussonetia kazinoki as Inhibitors of Nitric Oxide Production by Lee, Da Yeon, Lee, Hwa Jin, Ryu, Jae-Ha

“…Excessive nitric oxide (NO) production by macrophages has been involved in inflammatory diseases. Seven polyphenols ( - ) were isolated from and investigated…”
Get full text

Discovery of Tricyclic Pyranochromenone as Novel Bruton's Tyrosine Kinase Inhibitors with in Vivo Antirheumatic Activity by Cho, Hyewon, Lee, Eun, Kwon, Hye Ah, Seul, Lee, Jeon, Hui-Jeon, Yu, Ji Hoon, Ryu, Jae-Ha, Jeon, Raok

“…Bruton's tyrosine kinase (BTK) is an attractive target for treating patients with B cell malignancies and autoimmune diseases. Many BTK inhibitors have been…”
Get full text

Anti-inflammatory activity of sulfur-containing compounds from garlic by Lee, Da Yeon, Li, Hua, Lim, Hyo Jin, Lee, Hwa Jin, Jeon, Raok, Ryu, Jae-Ha

“…We identified four anti-inflammatory sulfur-containing compounds from garlic, and their chemical structures were identified as Z- and E-ajoene and oxidized…”
Get more information

Evodiamine selectively targets cancer stem-like cells through the p53-p21-Rb pathway by Han, Seula, Woo, Jong Kyu, Jung, Yuchae, Jeong, Dawoon, Kang, Minsook, Yoo, Young-Ji, Lee, Hani, Oh, Seung Hyun, Ryu, Jae-Ha, Kim, Woo-Young

“…In spite of the recent improvements, the resistance to chemotherapy/radiotherapy followed by relapse is the main hurdle for the successful treatment of breast…”
Get full text

A lignan from Alnus japonica inhibits glioblastoma tumorspheres by suppression of FOXM1 by Shim, Jin-Kyoung, Lim, Seung Hoon, Jeong, Ji Hye, Choi, Ran Joo, Oh, Yoojung, Park, Junseong, Choi, Sunghee, Hong, Junpyo, Kim, Seo Jin, Moon, Ju Hyung, Kim, Eui Hyun, Teo, Wan-Yee, Park, Bong Jin, Chang, Jong Hee, Ryu, Jae-Ha, Kang, Seok-Gu

“…Forkhead Box M1 (FOXM1) is known to regulate cell proliferation, apoptosis and tumorigenesis. The lignan, (−)-(2R,3R)-1,4-O-diferuloylsecoisolariciresinol…”
Get full text