Search Results - "Ryte, A S"
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Mechanism of Oligonucleotide Uptake by Cells: Involvement of Specific receptors?
Published in Proceedings of the National Academy of Sciences - PNAS (01-09-1989)“…We have investigated the interaction of oligonucleotides and their alkylating derivatives with mammalian cells. In experiments with L929 mouse fibroblast and…”
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Synthesis of alkylating oligonucleotide derivatives containing cholesterol or phenazinium residues at their 3′-terminus and their interaction with DNA within mammalian cells
Published in FEBS letters (28-08-1989)“…5′-[ 32P]-labelled alkylating decathymidylate [4-( N-2-chloroethyl) N-methylaminobenzyl]-5′-phosphamide derivatives containing cholesterol or phenazinium…”
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Interaction of cholesterol-conjugated alkylating oligonucleotide derivatives with cellular biopolymers
Published in FEBS letters (09-03-1992)“…Interactions of oligonucleotide derivatives with mammalian cells and cellular biopolymers have been investigated. The derivatives were oligonucleotides bearing…”
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Complementary addressed modification of nucleic acids with the alkylating derivatives of oligothymidylate ethyl phosphotriesters Effect of the phosphotriester fragments' configuration
Published in FEBS letters (15-08-1988)“…The alkylating derivatives of four individual diastereomers of the oligonucleotide [dTp(Et)] 3dTpU and two individual diastereomers of oligonucleotide…”
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Selective alkylation of poly(A) tracts of RNA inside the cell with the derivative of ethyl ester of oligothymidilate bearing 2-Chloroethylamino group
Published in FEBS letters (15-12-1980)Get full text
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Nucleotide and oligonucleotide derivatives as enzyme and nucleic acid targeted irreversible inhibitors. Biochemical aspects
Published in Advances in enzyme regulation (1985)“…Sequence specific modification of nucleic acids with reactive oligonucleotide derivatives, complementary addressed modification, can provide an efficient…”
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The effect of modification of terminal groups of oligonucleotides on their stability in mycoplasma culture
Published in Biopolimery i kletka (20-09-1991)“…The effect of modification of terminal groups of deoxyribooligonucleotides on their stability in culture medium and mycoplasma cells…”
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The efficient method for DNA encapsulation into reconstituted sendai virus envelopes
Published in Biopolimery i kletka (20-09-1988)“…The freezing-thawing method is used for encapsulation up to 17000 base pairs DNA into reconstituted Sendai virus envelopes (RSVE). It permits encapsulating up…”
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Sendai virus envelopes and erythrocyte ghosts as membrane vehicles for transport of the reactive oligonucleotide derivatives into the cells
Published in Biopolimery i kletka (20-07-1989)“…Poor penetration of oligonucleotide derivatives through mammalian cell membranes interferes with their action as inhibitors of cellular nucleic acid functions…”
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Uptake of oligonucleotide alkylating derivatives by the cells in the presence of substances stimulating transfection
Published in Biopolimery i kletka (20-07-1989)“…The effect of components facilitating transfection on the uptake of the alkylating 4-(N-2-chloroethyl-N-methylamino) -benzyl 5'-[…”
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