Search Results - "Ryskalin, Larisa"
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mTOR-Related Brain Dysfunctions in Neuropsychiatric Disorders
Published in International journal of molecular sciences (30-07-2018)“…The mammalian target of rapamycin (mTOR) is an ubiquitously expressed serine-threonine kinase, which senses and integrates several intracellular and…”
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The Autophagy Status of Cancer Stem Cells in Gliobastoma Multiforme: From Cancer Promotion to Therapeutic Strategies
Published in International journal of molecular sciences (05-08-2019)“…Glioblastoma multiforme (GBM) is the most common and aggressive primary brain tumor featuring rapid cell proliferation, treatment resistance, and tumor…”
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Phytochemicals Bridging Autophagy Induction and Alpha-Synuclein Degradation in Parkinsonism
Published in International journal of molecular sciences (03-07-2019)“…Among nutraceuticals, phytochemical-rich compounds represent a source of naturally-derived bioactive principles, which are extensively studied for potential…”
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The Multi-Faceted Effect of Curcumin in Glioblastoma from Rescuing Cell Clearance to Autophagy-Independent Effects
Published in Molecules (Basel, Switzerland) (20-10-2020)“…The present review focuses on the multi-faceted effects of curcumin on the neurobiology glioblastoma multiforme (GBM), with a special emphasis on autophagy…”
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Molecular Mechanisms Linking ALS/FTD and Psychiatric Disorders, the Potential Effects of Lithium
Published in Frontiers in cellular neuroscience (04-10-2019)“…Altered proteostasis, endoplasmic reticulum (ER) stress, abnormal unfolded protein response (UPR), mitochondrial dysfunction and autophagy impairment are…”
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mTOR-Dependent Cell Proliferation in the Brain
Published in BioMed research international (01-01-2017)“…The mammalian Target of Rapamycin (mTOR) is a molecular complex equipped with kinase activity which controls cell viability being key in the PI3K/PTEN/Akt…”
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The Effects of Amphetamine and Methamphetamine on the Release of Norepinephrine, Dopamine and Acetylcholine From the Brainstem Reticular Formation
Published in Frontiers in neuroanatomy (10-05-2019)“…Amphetamine (AMPH) and methamphetamine (METH) are widely abused psychostimulants, which produce a variety of psychomotor, autonomic and neurotoxic effects. The…”
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Ambiguous Effects of Autophagy Activation Following Hypoperfusion/Ischemia
Published in International journal of molecular sciences (13-09-2018)“…Autophagy primarily works to counteract nutrient deprivation that is strongly engaged during starvation and hypoxia, which happens in hypoperfusion…”
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Treatment of delayed union of the forearm with extracorporeal shockwave therapy: a case report and literature review
Published in Frontiers in endocrinology (Lausanne) (15-11-2023)“…Compared to other long bones, forearm fractures are particularly challenging due to the high rate of complications. These include malunion, delayed/nonunion,…”
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Neuroprotective Effects of Curcumin in Methamphetamine-Induced Toxicity
Published in Molecules (Basel, Switzerland) (24-04-2021)“…Curcumin (CUR), a natural polyphenol extracted from rhizome of the , has received great attention for its multiple potential health benefits as well as disease…”
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Prion Protein in Glioblastoma Multiforme
Published in International journal of molecular sciences (15-10-2019)“…The cellular prion protein (PrPc) is an evolutionarily conserved cell surface protein encoded by the gene. PrPc is ubiquitously expressed within nearly all…”
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Cell Clearing Systems Bridging Neuro-Immunity and Synaptic Plasticity
Published in International journal of molecular sciences (04-05-2019)“…In recent years, functional interconnections emerged between synaptic transmission, inflammatory/immune mediators, and central nervous system (CNS)…”
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Interdependency Between Autophagy and Synaptic Vesicle Trafficking: Implications for Dopamine Release
Published in Frontiers in molecular neuroscience (21-08-2018)“…Autophagy (ATG) and the Ubiquitin Proteasome (UP) are the main clearing systems of eukaryotic cells, in that being ultimately involved in degrading damaged and…”
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Molecular Mechanisms Underlying the Pain-Relieving Effects of Extracorporeal Shock Wave Therapy: A Focus on Fascia Nociceptors
Published in Life (Basel, Switzerland) (17-05-2022)“…In recent years, extracorporeal shock wave therapy (ESWT) has received increasing attention for its potential beneficial effects on various bone and…”
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Stoichiometric Analysis of Shifting in Subcellular Compartmentalization of HSP70 within Ischemic Penumbra
Published in Molecules (Basel, Switzerland) (11-06-2021)“…The heat shock protein (HSP) 70 is considered the main hallmark in preclinical studies to stain the peri-infarct region defined area penumbra in preclinical…”
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The Baseline Structure of the Enteric Nervous System and Its Role in Parkinson’s Disease
Published in Life (Basel, Switzerland) (22-07-2021)“…The gastrointestinal (GI) tract is provided with a peculiar nervous network, known as the enteric nervous system (ENS), which is dedicated to the fine control…”
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Early post-surgical rehabilitation and functional outcomes of a traumatic ulnar nerve injury: a pediatric case report
Published in Frontiers in neurology (07-02-2024)“…Peripheral nerve injuries (PNIs) of the upper limb are very common events within the pediatric population, especially following soft tissue trauma and bone…”
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Pain-Relieving Effects of Shockwave Therapy for Ledderhose Disease: An Ultrasound-Based Study of an Unusual Bilateral Case
Published in Life (Basel, Switzerland) (01-01-2024)“…Ledderhose disease (LD, or plantar fibromatosis) is a rare, nodular, hyperproliferative condition affecting the plantar aponeurosis of the foot. At present,…”
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The Autophagy-Related Organelle Autophagoproteasome Is Suppressed within Ischemic Penumbra
Published in International journal of molecular sciences (01-10-2021)“…The peri-infarct region, which surrounds the irreversible ischemic stroke area is named ischemic penumbra. This term emphasizes the borderline conditions for…”
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Lactoferrin Protects against Methamphetamine Toxicity by Modulating Autophagy and Mitochondrial Status
Published in Nutrients (25-09-2021)“…Lactoferrin (LF) was used at first as a vehicle to deliver non-soluble active compounds to the body, including the central nervous system (CNS). Nonetheless,…”
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