Search Results - "Ryoyama, K"

Selective toxicity of glycyrrhetinic acid against tumorigenic r/ m HM-SFME-1 cells is potentially attributed to downregulation of glutathione by Yamaguchi, H., Yu, T., Kidachi, Y., Akitaya, T., Yoshida, K., Kamiie, K., Noshita, T., Umetsu, H., Ryoyama, K.

“…Natural products from plants are expected to play significant roles in creating new, safe and improved chemopreventive and therapeutic antitumor agents…”
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Further cytological observation on 'activation' by superimposed antigen of inflammation-mediated macrophages by Hori, I, Ryoyama, K

“…Compact cell aggregates were induced by an injection of a superimposed antigen, sheep erythrocytes (SRBC) into PSK (a protein-bound polysaccharide)-'prepared'…”
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Anti-Tumor Activity of an Enzymatically Synthesized α-1,6 Branched α-1,4-Glucan, Glycogen by RYOYAMA, Kazuo, KIDACHI, Yumi, YAMAGUCHI, Hideaki, KAJIURA, Hideki, TAKATA, Hiroki

“…Oral administration of an enzymatically synthesized α-1,4:1,6-glycogen (ESG) at a dose of 50 μg/ml significantly prolonged the survival time of Meth A…”
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Machilin G and four neolignans from young fruits of Magnolia denudata show various degrees of inhibitory activity on nitric oxide (NO) production by Noshita, T.(Aomori Univ. (Japan)), Funayama, S, Hirakawa, T, Kidachi, Y, Ryoyama, K

“…Denudatin A and B, denudadione B, fargesone A and machilin G were isolated from Magnolia denudata. These compounds showed inhibitory effects on nitric oxide…”
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New cytotoxic phenolic derivatives from matured fruits of Magnolia denudata by Noshita, T.(Aomori Univ. (Japan)), Kiyota, H, Kidachi, Y, Ryoyama, K, Funayama, S, Hanada, K, Murayama, T

“…Magnolia species are widely cultivated in Japan as garden plants, and have been found to contain various compounds, including alkaloids, terpenoids, lignans,…”
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Selective sensitivity to wasabi-derived 6-(methylsulfinyl)hexyl isothiocyanate of human breast cancer and melanoma cell lines studied in vitro by Nomura, Takahiro, Shinoda, Shoko, Yamori, Takao, Sawaki, Saeko, Nagata, Ikuko, Ryoyama, Kazuo, Fuke, Yoko

“…Recently, attention has focused on the anticancer properties of an aromatic component 6-(methylsulfinyl)hexyl isothiocyanate (6-MITC) in a typical Japanese…”
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Studies on the Biological Properties of Coelomic Fluid of Sea Urchin. II. Naturally Occurring Hemagglutinin in Sea Urchin by Ryoyama, Kazuo

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The augmenting activity of 6-(Methylsulfinyl)hexyl isothiocyanate on cellular glutathione levels is less sensitive to thiol compounds than its cytotoxic activity by Kidachi, Y.(Aomori Univ. (Japan)), Noshita, T, Yamaguchi, H, Umetsu, H, Fuke, Y, Ryoyama, K

“…We analyzed the effects of thiol compounds on the biological activities of 6-(methylsulfinyl)hexyl isothiocyanate (6-MITC). Thiol compounds abolished the…”
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Appearance of a helper activity by mouse serum in cultured lymphoid cells by Ryoyama, K, Ryoyama, C

“…Manipulations which inhibit the development of non-specific suppressor T cells did not inhibit the development of a helper activity in culture. These…”
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Preventive effect of oral administration of 6-(methylsulfinyl)hexyl isothiocyanate derived from wasabi ( Wasabia japonica Matsum) against pulmonary metastasis of B16-BL6 mouse melanoma cells by Fuke, Yoko, Shinoda, Shoko, Nagata, Ikuko, Sawaki, Saeko, Murata, Mituyoshi, Ryoyama, Kazuo, Koizumi, Keiichi, Saiki, Ikuo, Nomura, Takahiro

“…Aim: Effect of oral administration of 6-(methylsulfinyl)hexyl isothiocyanate (6-MITC) or a 6-MITC-containing T-wasabi fraction from wasabi root ( Wasabia…”
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Enhancement of antileukemic effect in combination of 5-fluorouracil and OK-432 by Koshimura, S, Ryoyama, K

“…OK-432, a streptococcal preparation with potent antitumor activity, has been evaluated for its efficacy in experimental and clincal trials. This preparation,…”
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Cytotoxic sensitivity of the Yoshida sarcoma cell and its thio-TEPA-resistant subline against coelomic fluid preparation of the sea urchin in vitro by Ryoyama, K

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Increased synthesis of GFAP by TCDD in differentiation-disrupted SFME cells by Yamaguchi, Hideaki, Kidachi, Yumi, Ryoyama, Kazuo

“…The effects of 2,3,7,8-tetrachloro-dibenzo- p-dioxin (TCDD) on gene expression and synthesis of glial fibrillary acidic protein (GFAP) in…”
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Selective imbalances of cellular immune responses by adriamycin by Ehrke, M J, Ryoyama, K, Tomazic, V, Cohen, S A, Mihich, E

“…It has been demonstrated that spleen cells from mice treated with adriamycin not only develop an increased cell-mediated immune response during culture with…”
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Augmented gene expression of quinone reductase by 6-(methylsulfinyl)hexyl isothiocyanate through avoiding its cytotoxicity by Ryoyama, Kazuo, Mori, Naoto, Nara, Motoki, Kidachi, Yumi, Yamaguchi, Hideaki, Umetsu, Hironori, Fuke, Yoko

“…We examined both the induction of quinone reductase (QR) by 6-(methylsulfinyl)hexyl isothiocyanate and its cytotoxicity in Hepa1c1c7 cells, and compared the…”
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Effector molecules from antitumor macrophages induced with OK-432 and cyclophosphamide by RYOYAMA, K

“…The present study was designed to determine whether antitumor activity of macrophages induced with OK-432 and cyclophosphamide was mainly dependent on their…”
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Reduced antitumor and immune-adjuvant activities of the sub-cellular fractions from Group A Streptococcus by Ryoyama, K, Natsuume-Sakai, S, Hirota, H, Koshimura, S

“…The sub-cellular fractions from Group A streptococcus (Su-strain) were prepared, and their antitumor and biological activities were examined. The cell wall…”
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Studies on the properties of a streptococcal preparation OK-432 (NSC-B116209) as an immunopotentiator. I. Activation of serum complement components and peritoneal exudate cells by group A streptococcus by Sakai, S, Ryoyama, K, Koshimura, S, Migita, S

“…The inhibition of transplanted tumors in animals, which were previously injected with a streptococcal preparation, OK-432, has been suggestible to be induced…”
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EFFECT OF OK-432 ON IMMUNIZATION WITH MITOMYCIN-C-TREATED L1210 CELLS by RYOYAMA, Kazuo, MURAYAMA, Tsugiya, KOSHIMURA, Saburo

“…The pretreatment of B6D2F1 mice with OK-432 alone was not so effective to retard the growth of L1210 leukemia, and the leukemic cell was poorly immunogenic in…”
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Antitumor activity of protoplast membrane from group A streptococcus by Koshimura, S, Ryoyama, K, Ogawa, H, Yamamoto, A, Usami, H, Mitsui, H, Takagaki, Y

“…Cytoplasmic membrane of Group A streptococcus has been obtained by treatment of the cells with a phage-associated lytic enzyme to dissolve the streptococcal…”
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