Search Results - "Ryoo, Kanghyun"
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Spadin Modulates Astrocytic Passive Conductance via Inhibition of TWIK-1/TREK-1 Heterodimeric Channels
Published in International journal of molecular sciences (17-12-2020)“…Astrocytes, the most abundant cell type in the brain, are non-excitable cells and play critical roles in brain function. Mature astrocytes typically exhibit a…”
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2
TWIK-1/TASK-3 heterodimeric channels contribute to the neurotensin-mediated excitation of hippocampal dentate gyrus granule cells
Published in Experimental & molecular medicine (12-11-2018)“…Two-pore domain K + (K2P) channels have been shown to modulate neuronal excitability. The physiological role of TWIK-1, the first identified K2P channel, in…”
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3
Glutathione S-Transferase Mu Modulates the Stress-activated Signals by Suppressing Apoptosis Signal-regulating Kinase 1
Published in The Journal of biological chemistry (20-04-2001)“…Apoptosis signal-regulating kinase 1 (ASK1) is a mitogen-activated protein kinase kinase kinase that can activate the c-Jun N-terminal kinase and the p38…”
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4
Inhibition of Apoptosis Signal-regulating Kinase 1 by Nitric Oxide through a Thiol Redox Mechanism
Published in The Journal of biological chemistry (27-02-2004)“…Nitric oxide is an endogenous thiol-reactive molecule that modulates the functions of many regulatory proteins by a thiol-redox mechanism. NO has now been…”
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5
Heat Shock Protein Hsp72 Is a Negative Regulator of Apoptosis Signal-Regulating Kinase 1
Published in Molecular and Cellular Biology (01-11-2002)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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6
Negative Regulation of MEKK1-induced Signaling by Glutathione S-Transferase Mu
Published in The Journal of biological chemistry (15-10-2004)“…Mitogen-activated protein kinase/extracellular signal-regulated kinase kinase kinase 1 (MEKK1) is an important component in the stress-activated protein kinase…”
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7
Astrocytic NHERF ‐1 Increases Seizure Susceptibility by Inhibiting Surface Expression of TREK ‐1
Published in Glia (14-11-2024)“…ABSTRACT Mature hippocampal astrocytes exhibit a linear current‐to‐voltage (I‐V) K + membrane conductance called passive conductance. It is estimated to enable…”
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p57KIP2 Modulates Stress-activated Signaling by Inhibiting c-Jun NH2-terminal Kinase/Stress-activated Protein Kinase
Published in The Journal of biological chemistry (28-11-2003)“…p57 KIP2 , a member of the Cip/Kip family of enzymes that inhibit several cyclin-dependent kinases, plays a role in many biological events including cell…”
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9
Two-pore Domain Potassium Channels in Astrocytes
Published in Experimental neurobiology (01-10-2016)“…Two-pore domain potassium (K ) channels have a distinct structure and channel properties, and are involved in a background K current. The 15 members of the K…”
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10
Synapsins regulate BDNF-mediated synaptic potentiation and axon elongation by acting on membrane rafts
Published in The European journal of neuroscience (21-03-2017)“…In neurons, intracellular membrane rafts are essential for specific actions of brain-derived neurotrophic factor (BDNF), which include the regulation of axon…”
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11
TMEM16A expression in cholinergic neurons of the medial habenula mediates anxiety‐related behaviors
Published in EMBO reports (05-02-2020)“…TMEM16A, a Ca 2+ ‐activated Cl − channel, is known to modulate the excitability of various types of cells; however, its function in central neurons is largely…”
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12
Suppression of 14-3-3γ-mediated surface expression of ANO1 inhibits cancer progression of glioblastoma cells
Published in Scientific reports (23-05-2016)“…Anoctamin-1 (ANO1) acts as a Ca 2+ -activated Cl − channel in various normal tissues, and its expression is increased in several different types of cancer…”
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13
Synapsins regulate brain‐derived neurotrophic factor‐mediated synaptic potentiation and axon elongation by acting on membrane rafts
Published in The European journal of neuroscience (01-04-2017)“…In neurons, intracellular membrane rafts are essential for specific actions of brain‐derived neurotrophic factor (BDNF), which include the regulation of axon…”
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14
Surface expression of the Anoctamin-1 (ANO1) channel is suppressed by protein–protein interactions with β-COP
Published in Biochemical and biophysical research communications (24-06-2016)“…Anoctamin-1 (ANO1) is a Ca2+-activated chloride channel (CaCC) that plays important physiological roles in normal and cancerous tissues. However, the plasma…”
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15
RC3/neurogranin negatively regulates extracellular signal-regulated kinase pathway through its interaction with Ras
Published in Molecular and cellular biochemistry (01-04-2015)“…RC3/neurogranin is a postsynaptic protein and plays pivotal roles in spatial learning and emotional anxiety as well as synaptic plasticity. The expression…”
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Suppression of 14-3-3[gamma]-mediated surface expression of ANO1 inhibits cancer progression of glioblastoma cells
Published in Scientific reports (01-05-2016)“…Anoctamin-1 (ANO1) acts as a Ca2+ -activated Cl- channel in various normal tissues, and its expression is increased in several different types of cancer…”
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17
Identification of a Novel Antiapoptotic Protein That Antagonizes ASK1 and CAD Activities
Published in The Journal of cell biology (13-10-2003)“…Diverse stimuli initiate the activation of apoptotic signaling pathways that often causes nuclear DNA fragmentation. Here, we report a new antiapoptotic…”
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