Search Results - "Rymar, Vladimir"

A standardized accelerometry method for characterizing tremor: Application and validation in an ageing population with postural and action tremor by Gauthier-Lafreniere, Etienne, Aljassar, Meshal, Rymar, Vladimir V, Milton, John, Sadikot, Abbas F

“…Ordinal scales based on qualitative observation are the mainstay in the clinical assessment of tremor, but are limited by inter-rater reliability, measurement…”
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The netrin‐1 receptor DCC promotes the survival of a subpopulation of midbrain dopaminergic neurons: Relevance for ageing and Parkinson’s disease by Lo, Pik‐Shan, Rymar, Vladimir V., Kennedy, Timothy E., Sadikot, Abbas F.

“…Mechanisms that determine the survival of midbrain dopaminergic (mDA) neurons in the adult central nervous system (CNS) are not fully understood. Netrins are a…”
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The noradrenergic system is necessary for survival of vulnerable midbrain dopaminergic neurons: implications for development and Parkinson's disease by Hassani, Oum Kaltoum, Rymar, Vladimir V., Nguyen, Khanh Q., Huo, Lia, Cloutier, Jean-François, Miller, Freda D., Sadikot, Abbas F.

“…The cause of midbrain dopaminergic (mDA) neuron loss in sporadic Parkinson's disease (PD) is multifactorial, involving cell autonomous factors, cell-cell…”
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Serotonin4 (5-HT4) Receptor Agonists Are Putative Antidepressants with a Rapid Onset of Action by Lucas, Guillaume, Rymar, Vladimir V., Du, Jenny, Mnie-Filali, Ouissame, Bisgaard, Christina, Manta, Stella, Lambas-Senas, Laura, Wiborg, Ove, Haddjeri, Nasser, Piñeyro, Graciela, Sadikot, Abbas F., Debonnel, Guy

“…Current antidepressants are clinically effective only after several weeks of administration. Here, we show that serotonin4(5-HT4) agonists reduce immobility in…”
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Serotonin(4) (5-HT(4)) receptor agonists are putative antidepressants with a rapid onset of action by Lucas, Guillaume, Rymar, Vladimir V, Du, Jenny, Mnie-Filali, Ouissame, Bisgaard, Christina, Manta, Stella, Lambas-Senas, Laura, Wiborg, Ove, Haddjeri, Nasser, Piñeyro, Graciela, Sadikot, Abbas F, Debonnel, Guy

“…Current antidepressants are clinically effective only after several weeks of administration. Here, we show that serotonin(4) (5-HT(4)) agonists reduce…”
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Laminar fate of cortical GABAergic interneurons is dependent on both birthdate and phenotype by Rymar, Vladimir V., Sadikot, Abbas F.

“…Pioneering work indicates that the final position of neurons in specific layers of the mammalian cerebral cortex is determined primarily by birthdate…”
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The primate centromedian–parafascicular complex: Anatomical organization with a note on neuromodulation by Sadikot, Abbas F, Rymar, Vladimir V

“…Abstract In addition to the cerebral cortex, the striatum receives excitatory input from the thalamus. The centromedian (centre median, CM) and parafascicular…”
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Impaired TrkB Signaling Underlies Reduced BDNF-Mediated Trophic Support of Striatal Neurons in the R6/2 Mouse Model of Huntington's Disease by Nguyen, Khanh Q, Rymar, Vladimir V, Sadikot, Abbas F

“…The principal projection neurons of the striatum are critically dependent on an afferent supply of brain derived neurotrophic factor (BDNF) for neurotrophic…”
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Thalamostriatal degeneration contributes to dystonia and cholinergic interneuron dysfunction in a mouse model of Huntington's disease by Crevier-Sorbo, Gabriel, Rymar, Vladimir V, Crevier-Sorbo, Raphael, Sadikot, Abbas F

“…Huntington's disease (HD) is an autosomal dominant trinucleotide repeat disorder characterized by choreiform movements, dystonia and striatal neuronal loss…”
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The transcription factor Pitx3 is expressed selectively in midbrain dopaminergic neurons susceptible to neurodegenerative stress by Luk, Kelvin C., Rymar, Vladimir V., den Munckhof, Pepijn, Nicolau, Stefan, Steriade, Claude, Bifsha, Panojot, Drouin, Jacques, Sadikot, Abbas F.

“…The homeodomain transcription factor Pitx3 is critical for the survival of midbrain dopaminergic (mDA) neurons. Pitx3‐deficient mice exhibit severe but…”
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BAG3P215L/KO Mice as a Model of BAG3P209L Myofibrillar Myopathy by Robertson, Rebecca, Conte, Talita C., Dicaire, Marie-Josée, Rymar, Vladimir V., Sadikot, Abbas F., Bryson-Richardson, Robert J., Lavoie, Josée N., O'Ferrall, Erin, Young, Jason C., Brais, Bernard

“…BCL-2–associated athanogene 3 (BAG3) is a co-chaperone to heat shock proteins important in degrading misfolded proteins through chaperone-assisted selective…”
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Glutamate corelease promotes growth and survival of midbrain dopamine neurons by Fortin, Guillaume M, Bourque, Marie-Josée, Mendez, Jose Alfredo, Leo, Damiana, Nordenankar, Karin, Birgner, Carolina, Arvidsson, Emma, Rymar, Vladimir V, Bérubé-Carrière, Noémie, Claveau, Anne-Marie, Descarries, Laurent, Sadikot, Abbas F, Wallén-Mackenzie, Åsa, Trudeau, Louis-Éric

“…Recent studies have proposed that glutamate corelease by mesostriatal dopamine (DA) neurons regulates behavioral activation by psychostimulants. How and when…”
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p73 Regulates Neurodegeneration and Phospho-Tau Accumulation during Aging and Alzheimer's Disease by Wetzel, Monica K., Naska, Sibel, Laliberté, Christine L., Rymar, Vladimir V., Fujitani, Masashi, Biernaskie, Jeffrey A., Cole, Christy J., Lerch, Jason P., Spring, Shoshana, Wang, S.-H., Frankland, Paul W., Henkelman, R. Mark, Josselyn, Sheena A., Sadikot, Abbas F., Miller, Freda D., Kaplan, David R.

“…The genetic mechanisms that regulate neurodegeneration are only poorly understood. We show that the loss of one allele of the p53 family member, p73, makes…”
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Flow-based fiber tracking with diffusion tensor and q-ball data: Validation and comparison to principal diffusion direction techniques by Campbell, Jennifer S.W., Siddiqi, Kaleem, Rymar, Vladimir V., Sadikot, Abbas F., Pike, G. Bruce

“…In this study, we evaluate the performance of a flow-based surface evolution fiber tracking algorithm by means of a physical anisotropic diffusion phantom with…”
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Neurogenesis and stereological morphometry of calretinin-immunoreactive GABAergic interneurons of the neostriatum by Rymar, Vladimir V., Sasseville, Rachel, Luk, Kelvin C., Sadikot, Abbas F.

“…We determined the neurogenesis characteristics of a distinct subclass of rat striatum γ‐aminobutyric acidergic (GABAergic) interneurons expressing the…”
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Group I mGluR5 metabotropic glutamate receptors regulate proliferation of neuronal progenitors in specific forebrain developmental domains by Gandhi, Rina, Luk, Kelvin C, Rymar, Vladimir V, Sadikot, Abbas F

“…Major classical neurotransmitters including GABA and glutamate play novel morphogenic roles during development of the mammalian CNS. During forebrain…”
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p73 Is Required for Survival and Maintenance of CNS Neurons by Pozniak, Christine D, Barnabe-Heider, Fanie, Rymar, Vladimir V, Lee, Anna F, Sadikot, Abbas F, Miller, Freda D

“…Here, we show that the p53 family member, p73, is necessary for survival and long-term maintenance of CNS neurons, including postnatal cortical neurons. In…”
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Creation of Computerized 3D MRI-Integrated Atlases of the Human Basal Ganglia and Thalamus by Sadikot, Abbas F, Chakravarty, M Mallar, Bertrand, Gilles, Rymar, Vladimir V, Al-Subaie, Fahd, Collins, D Louis

“…Functional brain imaging and neurosurgery in subcortical areas often requires visualization of brain nuclei beyond the resolution of current magnetic resonance…”
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Morphine-induced changes in delta opioid receptor trafficking are linked to somatosensory processing in the rat spinal cord by Morinville, Anne, Cahill, Catherine M, Aibak, Haneen, Rymar, Vladimir V, Pradhan, Amynah, Hoffert, Cyrla, Mennicken, Françoise, Stroh, Thomas, Sadikot, Abbas F, O'Donnell, Dajan, Clarke, Paul B S, Collier, Brian, Henry, James L, Vincent, Jean-Pierre, Beaudet, Alain

“…An in vivo fluorescent deltorphin (Fluo-DLT) internalization assay was used to assess the distribution and regulation of pharmacologically available delta…”
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Defective Fas expression exacerbates neurotoxicity in a model of Parkinson's disease by Landau, Anne M, Luk, Kelvin C, Jones, Michelle-Lee, Siegrist-Johnstone, Rosmarie, Young, Yoon Kow, Kouassi, Edouard, Rymar, Vladimir V, Dagher, Alain, Sadikot, Abbas F, Desbarats, Julie

“…Fas (CD95), a member of the tumor necrosis factor-receptor superfamily, has been studied extensively as a death-inducing receptor in the immune system…”
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