Search Results - "Rykowski, Sebastian"

Design, Synthesis, and Evaluation of Novel 3-Carboranyl-1,8-Naphthalimide Derivatives as Potential Anticancer Agents by Rykowski, Sebastian, Gurda-Woźna, Dorota, Orlicka-Płocka, Marta, Fedoruk-Wyszomirska, Agnieszka, Giel-Pietraszuk, Małgorzata, Wyszko, Eliza, Kowalczyk, Aleksandra, Stączek, Paweł, Bak, Andrzej, Kiliszek, Agnieszka, Rypniewski, Wojciech, Olejniczak, Agnieszka B

“…We synthesized a series of novel 3-carboranyl-1,8-naphthalimide derivatives, mitonafide and pinafide analogs, using click chemistry, reductive amination and…”
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Cytotoxic effects of halophilic archaea metabolites on ovarian cancer cell lines by Kowalewicz-Kulbat, Magdalena, Krawczyk, Krzysztof T, Szulc-Kielbik, Izabela, Rykowski, Sebastian, Denel-Bobrowska, Marta, Olejniczak, Agnieszka B, Locht, Camille, Klink, Magdalena

“…Abstract Background Ovarian cancer is one of the most frequent and deadly gynaecological cancers, often resistant to platinum-based chemotherapy, the current…”
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Carboranyl-1,8-naphthalimide intercalators induce lysosomal membrane permeabilization and ferroptosis in cancer cell lines by Rykowski, Sebastian, Gurda-Woźna, Dorota, Fedoruk-Wyszomirska, Agnieszka, Orlicka-Płocka, Marta, Kowalczyk, Aleksandra, Stączek, Paweł, Denel-Bobrowska, Marta, Biniek-Antosiak, Katarzyna, Rypniewski, Wojciech, Wyszko, Eliza, Olejniczak, Agnieszka B.

“…The synthesis of carborane-1,8-naphthalimide conjugates and evaluation of their DNA-binding ability and anticancer activity were performed. A series of…”
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Design of DNA Intercalators Based on 4-Carboranyl-1,8-Naphthalimides: Investigation of Their DNA-Binding Ability and Anticancer Activity by Rykowski, Sebastian, Gurda-Woźna, Dorota, Orlicka-Płocka, Marta, Fedoruk-Wyszomirska, Agnieszka, Giel-Pietraszuk, Małgorzata, Wyszko, Eliza, Kowalczyk, Aleksandra, Stączek, Paweł, Biniek-Antosiak, Katarzyna, Rypniewski, Wojciech, Olejniczak, Agnieszka B

“…In the present study, we continue our work related to the synthesis of 1,8-naphthalimide and carborane conjugates and the investigation of their anticancer…”
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PPE51 Is Involved in the Uptake of Disaccharides by Mycobacterium tuberculosis by Korycka-Machała, Małgorzata, Pawełczyk, Jakub, Borówka, Paulina, Dziadek, Bożena, Brzostek, Anna, Kawka, Malwina, Bekier, Adrian, Rykowski, Sebastian, Olejniczak, Agnieszka B, Strapagiel, Dominik, Witczak, Zbigniew, Dziadek, Jarosław

“…We have recently found that selected -disaccharides possess bactericidal effects against but not against or S . Here, we selected spontaneous mutants…”
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Naphthalimides Selectively Inhibit the Activity of Bacterial, Replicative DNA Ligases and Display Bactericidal Effects against Tubercle Bacilli by Korycka-Machala, Malgorzata, Nowosielski, Marcin, Kuron, Aneta, Rykowski, Sebastian, Olejniczak, Agnieszka, Hoffmann, Marcin, Dziadek, Jaroslaw

“…The DNA ligases, enzymes that seal breaks in the backbones of DNA, are essential for all organisms, however bacterial ligases essential for DNA replication use…”
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(1–4)-Thiodisaccharides as anticancer agents. Part 5. Evaluation of anticancer activity and investigation of mechanism of action by Sarnik, Joanna, Gajek, Arkadiusz, Toma, Monika, Pawelczyk, Jakub, Rykowski, Sebastian, Olejniczak, Agnieszka, Sliwinski, Tomasz, Bielski, Roman, Witczak, Zbigniew J., Poplawski, Tomasz

“…[Display omitted] (1–4)-Thiodisaccharides, thiosugars with the 1–4-thio bridge, were recently shown to induce oxidative stress, as well as, apoptosis in cancer…”
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Synthesis and in vitro cytotoxic activity of dye-linker-macrocycle conjugates with variable linker length and components by Tomczyk, Mateusz D., Matczak, Karolina, Skonieczna, Magdalena, Chulkin, Pavel, Denel-Bobrowska, Marta, Różycka, Daria, Rykowski, Sebastian, Olejniczak, Agnieszka B., Walczak, Krzysztof

“…[Display omitted] •The structure–activity relationship was established for multiple series of conjugates.•The biological activity of the conjugates was…”
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Synthesis of naphthalimide-carborane and metallacarborane conjugates: Anticancer activity, DNA binding ability by Nekvinda, Jan, Różycka, Daria, Rykowski, Sebastian, Wyszko, Eliza, Fedoruk-Wyszomirska, Agnieszka, Gurda, Dorota, Orlicka-Płocka, Marta, Giel-Pietraszuk, Małgorzata, Kiliszek, Agnieszka, Rypniewski, Wojciech, Bachorz, Rafał, Wojcieszak, Jakub, Grüner, Bohumir, Olejniczak, Agnieszka B.

“…[Display omitted] •A series of naphthalimide-carborane/metallacarborane conjugates were synthesized.•First example of X-ray analysis of naphthalimide-carborane…”
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