Search Results - "Rye, Daphne"
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Switch-like Responses of Two Cholesterol Sensors Do Not Require Protein Oligomerization in Membranes
Published in Biophysical journal (24-03-2015)“…Many cellular processes are sensitive to levels of cholesterol in specific membranes and show a strongly sigmoidal dependence on membrane composition. The…”
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A cholesterol-binding bacterial toxin provides a strategy for identifying a specific Scap inhibitor that blocks lipid synthesis in animal cells
Published in Proceedings of the National Academy of Sciences - PNAS (13-02-2024)“…Lipid synthesis is regulated by the actions of Scap, a polytopic membrane protein that binds cholesterol in membranes of the endoplasmic reticulum (ER). When…”
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Journal Article