Search Results - "Ryckelynck, M."

Combi-seq for multiplexed transcriptome-based profiling of drug combinations using deterministic barcoding in single-cell droplets by Mathur, L., Szalai, B., Du, N. H., Utharala, R., Ballinger, M., Landry, J. J. M., Ryckelynck, M., Benes, V., Saez-Rodriguez, J., Merten, C. A.

“…Anti-cancer therapies often exhibit only short-term effects. Tumors typically develop drug resistance causing relapses that might be tackled with drug…”
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Transient compartmentalization of RNA replicators prevents extinction due to parasites by Matsumura, Shigeyoshi, Kun, Ádám, Ryckelynck, Michael, Coldren, Faith, Szilágyi, András, Jossinet, Fabrice, Rick, Christian, Nghe, Philippe, Szathmáry, Eörs, Griffiths, Andrew D.

“…The appearance of molecular replicators (molecules that can be copied) was probably a critical step in the originz of life. However, parasitic replicators…”
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Fluorescence-activated droplet sorting (FADS): efficient microfluidic cell sorting based on enzymatic activity by Baret, Jean-Christophe, Miller, Oliver J, Taly, Valerie, Ryckelynck, Michaël, El-Harrak, Abdeslam, Frenz, Lucas, Rick, Christian, Samuels, Michael L, Hutchison, J Brian, Agresti, Jeremy J, Link, Darren R, Weitz, David A, Griffiths, Andrew D

“…We describe a highly efficient microfluidic fluorescence-activated droplet sorter (FADS) combining many of the advantages of microtitre-plate screening and…”
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Multi-step microfluidic droplet processing: kinetic analysis of an in vitro translated enzyme by Mazutis, Linas, Baret, Jean-Christophe, Treacy, Patrick, Skhiri, Yousr, Araghi, Ali Fallah, Ryckelynck, Michael, Taly, Valérie, Griffiths, Andrew D

“…Microdroplets in water-in-oil emulsions can be used as microreactors with volumes 10(3) to 10(9) times smaller than the smallest working volumes in a…”
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tRNA-balanced expression of a eukaryal aminoacyl-tRNA synthetase by an mRNA-mediated pathway by Frugier, Magali, Ryckelynck, Michaël, Giegé, Richard

“…Aminoacylation of transfer RNAs is a key step during translation. It is catalysed by the aminoacyl‐tRNA synthetases (aaRSs) and requires the specific…”
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tRNAs and tRNA mimics as cornerstones of aminoacyl-tRNA synthetase regulations by Ryckelynck, Michaël, Giegé, Richard, Frugier, Magali

“…Structural plasticity of transfer RNA (tRNA) molecules is essential for interactions with their biological partners in aminoacylation reactions and during…”
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An Intricate RNA Structure with two tRNA-derived Motifs Directs Complex Formation between Yeast Aspartyl-tRNA Synthetase and its mRNA by Ryckelynck, Michaël, Masquida, Benoit, Giegé, Richard, Frugier, Magali

“…Accurate translation of genetic information necessitates the tuned expression of a large group of genes. Amongst them, controlled expression of the enzymes…”
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Yeast tRNA(Asp) charging accuracy is threatened by the N-terminal extension of aspartyl-tRNA synthetase by Ryckelynck, Michaël, Giegé, Richard, Frugier, Magali

“…This study evaluates the role of the N-terminal extension from yeast aspartyl-tRNA synthetase in tRNA aspartylation. The presence of an RNA-binding motif in…”
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Yeast tRNA super(Asp) Charging Accuracy Is Threatened by the N-terminal Extension of Aspartyl-tRNA Synthetase by Ryckelynck, M, Giege, R, Frugier, M

“…This study evaluates the role of the N-terminal extension from yeast aspartyl-tRNA synthetase in tRNA aspartylation. The presence of an RNA-binding motif in…”
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