Search Results - "Ryberg, Line A"

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  1. 1

    Oligomerization of a Glucagon-like Peptide 1 Analog: Bridging Experiment and Simulations by Frederiksen, Tine M., Sønderby, Pernille, Ryberg, Line A., Harris, Pernille, Bukrinski, Jens T., Scharff-Poulsen, Anne M., Elf-Lind, Maria N., Peters, Günther H.

    Published in Biophysical journal (15-09-2015)
    “…The glucagon-like peptide 1 (GLP-1) analog, liraglutide, is a GLP-1 agonist and is used in the treatment of type-2 diabetes mellitus and obesity. From a…”
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    Journal Article
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    Substrates and Cyclic Peptide Inhibitors of the Oligonucleotide‐Activated Sirtuin 7 by Bolding, Julie E., Nielsen, Alexander L., Jensen, Iben, Hansen, Tobias N., Ryberg, Line A., Jameson, Samuel T., Harris, Pernille, Peters, Günther H. J., Denu, John M., Rogers, Joseph M., Olsen, Christian A.

    Published in Angewandte Chemie International Edition (04-12-2023)
    “…The sirtuins are NAD+‐dependent lysine deacylases, comprising seven isoforms (SIRT1–7) in humans, which are involved in the regulation of a plethora of…”
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    Journal Article
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    Investigations of Albumin–Insulin Detemir Complexes Using Molecular Dynamics Simulations and Free Energy Calculations by Ryberg, Line A, Sønderby, Pernille, Bukrinski, Jens T, Harris, Pernille, Peters, Günther H. J

    Published in Molecular pharmaceutics (06-01-2020)
    “…Insulin detemir is a lipidated insulin analogue that obtains a half-life extension by oligomerization and reversible binding to human serum albumin. In the…”
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  6. 6

    Solution structures of long‐acting insulin analogues and their complexes with albumin by Ryberg, Line A., Sønderby, Pernille, Barrientos, Fabian, Bukrinski, Jens T., Peters, Günther H. J., Harris, Pernille

    “…The lipidation of peptide drugs is one strategy to obtain extended half‐lives, enabling once‐daily or even less frequent injections for patients. The half‐life…”
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    Journal Article
  7. 7

    Substrates and Cyclic Peptide Inhibitors of the Oligonucleotide‐Activated Sirtuin 7 by Bolding, Julie E., Nielsen, Alexander L., Jensen, Iben, Hansen, Tobias N., Ryberg, Line A., Jameson, Samuel T., Harris, Pernille, Peters, Günther H. J., Denu, John M., Rogers, Joseph M., Olsen, Christian A.

    Published in Angewandte Chemie (04-12-2023)
    “…The sirtuins are NAD+‐dependent lysine deacylases, comprising seven isoforms (SIRT1–7) in humans, which are involved in the regulation of a plethora of…”
    Get full text
    Journal Article