Search Results - "Rybalchenko, K."

Anti-Inflammatory Effects of Protein Kinase Inhibitor Pyrrol Derivate by Ogloblya, Olexandr V., Kotlyar, Iryna P., Yena, Maryna S., Kuznietsova, Halyna M., Rybalchenko, Volodymyr K.

“…In our previous studies we showed antitumor and anti-inflammatory activities of protein kinases inhibitor pyrrol derivate…”
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The effect of Amaranth oil on monolayers of artificial lipids and hepatocyte plasma membranes with adrenalin-induced stress by Yelisyeyeva, O.P., Semen, K.O., Ostrovska, G.V., Kaminskyy, D.V., Sirota, T.V., Zarkovic, N., Mazur, D., Lutsyk, O.D., Rybalchenko, K., Bast, A.

“…•Prooxidant activity of Amaranth oil is revealed in adrenalin autooxidation reaction.•Amaranth oil modulates the physical chemical properties of…”
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Effects of 5-Amyno-4-(1,3-benzothyazol-2-yn)-1-(3-methoxyphenyl)-1,2-dihydro-3H-pyrrol-3-one Intake on Digestive System in a Rat Model of Colon Cancer by Rybalchenko, Volodymyr K., Kotlyar, Iryna P., Luzhenetska, Valentyna K., Kuznietsova, Halyna M.

“…Introduction. Pyrrol derivate 5-amyno-4-(1,3-benzothyazol-2-yn)-1-(3-methoxyphenyl)-1,2-dihydro-3H-pyrrol-3-one (D1) has shown antiproliferative activities in…”
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Effect of pyrrole derivatives on manifestations of inflammation in rats with chronic ulcerative colitis under prednisolone treatment by Kotlyar, I. P., Kuznietsova, H. M., Rybalchenko, V. K.

“…Background. Previously, we have detected the antitumor and anti-inflammatory activities of pyrrole-derived protein kinase inhibitors - MI-1…”
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Cytotoxic action of maleimide derivative 1-(4-Cl-benzyl)-3-chloro-4-(CF(3)-phenylamino)-1H-pyrrole-2,5-dione toward mammalian tumor cells and its capability to interact with DNA by Finiuk, N. S., Ivasechko, I. I., Klyuchivska, O. Yu, Kuznietsova, H. M., Rybalchenko, V. K., Stoika, R. S.

“…Development of chemical compounds capable to supress tumor progression is a perspective strategy of cancer treatment. Heterocyclic compounds possess a broad…”
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Inhibitor of protein kinases 1-(4-chlorobenzyl)-3-chloro-4-(3-trifluoromethylphenylamino)-1Н-pyrrole-2,5-dione induces DNA damage and apoptosis in human colon carcinoma cells by Finiuk, N. S., Klyuchivska, O. Yu, Kuznietsova, H. M., Vashchuk, S. P., Rybalchenko, V. K., Stoika, R. S.

“…Background. The heterocyclic scaffolds are in the list of key structural blocks used at synthesis of novel biologically active compounds. Materials and…”
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In vitro and in vivo toxicity of pristine C60 fullerene aqueous colloid solution by Prylutska, Svitlana V., Grebinyk, Anna G., Lynchak, Oksana V., Byelinska, Iryna V., Cherepanov, Vsevolod V., Tauscher, Eric, Matyshevska, Olga P., Prylutskyy, Yuriy I., Rybalchenko, Volodymyr K., Ritter, Uwe, Frohme, Marcus

“…Toxicity of the C 60 fullerene aqueous colloid solution in vitro and in vivo experiments was studied. C 60 fullerene in the concentration range of 3.6-144…”
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INFLUENCE OF C60-FULLERENE AQUEOUS COLLOID SOLUTION ON LIVER AND PANCREAS MORPHOLOGICAL STATE AND BLOOD AMINOTRANSFERASES OF RATS WITH EXPERIENCED ACUTE CHOLANGITIS by Dziubenko, N V, Kuznietsova, H M, Lynchak, O V, Rybalchenko, V K

“…Aim of the work was to investigate the suspended C60-fulleren effect on liver and pancreas state under intraperitoneal and intragastrial administration on rat…”
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Conceptual model of management the vital state plant eсomorрhs by the criteria of adaptation mechanisms by T. Z. Moskalets, V. K. Rybalchenko

“…On the basis of representatives of the tribe Triticеae (Triticum аestivum L., T. trispecies Shulind, Secale cereale L.) we have developed a conceptual model of…”
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Comparative Analysis of the Antineoplastic Activity of C60 Fullerene with 5-Fluorouracil and Pyrrole Derivative In Vivo by Lynchak, O. V., Prylutskyy, Yu I., Rybalchenko, V. K., Kyzyma, O. A., Soloviov, D., Kostjukov, V. V., Evstigneev, M. P., Ritter, U., Scharff, P.

“…The antitumor activity of pristine C 60 fullerene aqueous solution (C 60 FAS) compared to 5-fluorouracil (5-FU) and pyrrole derivative…”
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Comparative Analysis of the Antineoplastic Activity of C 60 Fullerene with 5-Fluorouracil and Pyrrole Derivative In Vivo by Lynchak, O V, Prylutskyy, Yu I, Rybalchenko, V K, Kyzyma, O A, Soloviov, D, Kostjukov, V V, Evstigneev, M P, Ritter, U, Scharff, P

“…The antitumor activity of pristine C fullerene aqueous solution (C FAS) compared to 5-fluorouracil (5-FU) and pyrrole derivative 1-(4-Cl-benzyl)-3-Cl-4-(CF…”
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Water-soluble C60 fullerenes reduce manifestations of acute cholangitis in rats by Kuznietsova, H. M., Lynchak, O. V., Dziubenko, N. V., Osetskyi, V. L., Ogloblya, O. V., Prylutskyy, Yu I., Rybalchenko, V. K., Ritter, U., Scharff, P.

“…Sclerosing cholangitis is the liver disease of uncertain etiology, extremely unfavorable prognosis and lack of effective medication therapy. Therefore, the…”
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Impact of dihydropyrrol derivative on the normal colonic mucosa of DMH-induced colon cancer rats compared with 5-fluorouracil by Kuznietsova, H M, Ogloblya, O V, Rybalchenko, V K

“…To compare the effects of cytostatic compound dihydropyrrol derivative (D1, 5-amyno-4-(1,3-benzothyazol-2-yl)-1-(3-methoxyphenyl)-1,2-dihydro-3Н-pyrrol-3-one)…”
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Synthesis and biological activity of 4-amino-3-chloro-1H-pyrrole-2,5-diones by Kuznietsova, Halyna M., Hurmach, Vasyl V., Bychko, Andriy V., Tykhoniuk, Olena I., Milokhov, Demyd S., Khilya, Olga V., Volovenko, Yulian M., Rybalchenko, Volodymyr K.

“…4-Amino-3-chloro-1 H -pyrrole-2,5-dione derivatives were designed and synthesized as potential tyrosine kinase inhibitors. One of them has been shown to…”
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INFLUENCE OF NEUROTROPIC AND METABOLIC DRUGS ON STRUCTURAL AND FUNCTIONAL STATE OF LIPID MATRIX OF THE CELL MEMBRANE by Seba, M. V., Khomenko, M. O., Nosevych, D. K., Golubev, M. I., Kaplunenko, V. G., Byelinska, I. V., Rybalchenko, V. K.

“…Lately, more and more often to stimulate the reproductive function of animals people use biochemical products, which are based on neurotropic and metabolic…”
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Effect of С60 fullerenes on the intensity of colon damage and hematological signs of ulcerative colitis in rats by Byelinska, I.V., Kuznietsova, H.M., Dziubenko, N.V., Lynchak, O.V., Rybalchenko, T.V., Prylutskyy, Yu.I., Kyzyma, O.A., Ivankov, O., Rybalchenko, V.K., Ritter, U.

“…The application of pristine С60 fullerene aqueous colloid solution (C60FAS; 0.5 mg/kg body weight) for rats experienced acute colitis, either intraperitoneally…”
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RNA interference of genes of ubiquitn and proteasome β7 subunit in cardiomyocytes culture by Kyrychenko, V. O., Nagibin, V. S., Tumanovska, L. V., Rybalchenko, V. K., Dosenko, V. E., Moibenko, O. O.

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In vitro and in vivo toxicity of pristine C 60 fullerene aqueous colloid solution by Prylutska, Svitlana V., Grebinyk, Anna G., Lynchak, Oksana V., Byelinska, Iryna V., Cherepanov, Vsevolod V., Tauscher, Eric, Matyshevska, Olga P., Prylutskyy, Yuriy I., Rybalchenko, Volodymyr K., Ritter, Uwe, Frohme, Marcus

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Effect of maleimide derivative on the morpho-functional state of the kidney in experimental colon carcinogenesis in rats by Kharchuk, I V, Filins'ka, O M, Iablons'ka, S V, Rybal'chenko, V K

“…The effect of long-term administration of the novel maleimide derivative with antiproliferative activity on kidney morpho-functional state in experimental…”
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Models of Nanocomplexes Based on C60 Fullerene for Creation of Anticancer and Anti-Inflammatory Agents

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