Search Results - "Rybak, L.P"

Expression of the kidney injury molecule 1 in the rat cochlea and induction by cisplatin by Mukherjea, D., Whitworth, C.A., Nandish, S., Dunaway, G.A., Rybak, L.P., Ramkumar, V.

“…Cisplatin is a widely used chemotherapeutic agent whose dose-limiting side effects include ototoxicity and nephrotoxicity. Recent evidence indicates that…”
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Responses of antioxidant system to acute and trained exercise in rat heart subcellular fractions by Somani, S.M., Frank, S., Rybak, L.P.

“…The effects of acute and trained exercise on antioxidant enzymes (AOE), glutathione (GSH), and malondialdehyde (MDA) were compared in rat heart subcellular…”
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Effect of exercise training on antioxidant system in brain regions of rat by Rybak, L.P., Somani, S.M., Ravi, R.

“…The purpose of this investigation was to determine whether any alterations in antioxidant enzyme activities and levels of glutathione (GSH) in brain regions…”
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Ototoxicity by Rybak, L.P., Ramkumar, V.

“…This paper reviews intriguing recent findings on the mechanisms of drug induced hearing loss caused by two major classes of therapeutic agents: the…”
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Dose response of ethanol on antioxidant defense system of liver, lung, and kidney in rat by Scott, R.B, Reddy, K.S, Husain, K, Schlorff, E.C, Rybak, L.P, Somani, S.M

“…This study investigated the alterations in levels of glutathione, lipid peroxidation, and antioxidant enzyme activity in the liver, lung, and kidney of rats…”
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Noise in animal facilities: why it matters by Turner, Jeremy G, Bauer, Carol A, Rybak, Leonard P

“…Environmental noise can alter endocrine, reproductive and cardiovascular function, disturb sleep/wake cycles, and can mask normal communication between…”
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Carboplatin-induced oxidative stress in rat cochlea by Husain, K., Whitworth, C., Somani, S.M., Rybak, L.P.

“…Carboplatin is currently being used in the clinic against a variety of human cancers. However, high dose carboplatin chemotherapy resulted in ototoxicity in…”
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Time response of carboplatin-induced hearing loss in rat by Husain, K., Scott, B., Whitworth, C., Rybak, L.P.

“…Carboplatin is currently being used as an anticancer drug against human cancers. However, high dose of carboplatin chemotherapy resulted in hearing loss in…”
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Dose response of carboplatin-induced hearing loss in rats: antioxidant defense system by HUSAIN, K, SCOTT, R. B, WHITWORTH, C, SOMANI, S. M, RYBAK, L. P

“…Carboplatin, a platinum-containing anticancer drug, is currently being used against a variety of cancers. However, a single high dose of carboplatin is…”
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Hearing: the effects of chemicals by Rybak, L P

“…Recent studies of human beings exposed to environmental chemicals, as well as experimental animal studies, have identified a number of chemical agents that are…”
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Comparative acute ototoxicity of loop diuretic compounds by Rybak, L P, Whitworth, C, Scott, V

“…A microelectrode was used to measure endocochlear potentials (EP) in adult chinchillas and to study the effects of a series of loop diuretics. EP was measured…”
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Kinocilia in the developing stria vascularis of the rat pup by WHITWORTH, C, WEBERG, A, WAGAHOFF, D, RYBAK, L. P

“…The mammalian stria vascularis undergoes certain developmental changes in the postnatal rat. The present study was designed to examine the ultrastructure of…”
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Nature of blood-labyrinth barrier in experimental conditions by Juhn, S K, Rybak, L P, Prado, S

“…The blood-labyrinth barrier is concept that has evolved based on marked difference in chemical composition between perilymph and blood. Studies reported here…”
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Organic acids do not alter the cochlear effects of ethacrynic acid by Rybak, L P, Whitworth, C, Scott, V

“…Previous studies have shown a reduction of the ototoxicity of furosemide in chinchillas pretreated with organic acid transport inhibitors. The current studies…”
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Effects of organic acids on stria vascularis ultrastructure and function in the chinchilla by RYBAK, L. P, WEBERG, A, WHITWORTH, C, SCOTT, V

“…The purpose of this study was to compare the effects of several organic acids (probenecid, sodium salicylate and penicillin G) on the endocochlear potential…”
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In situ real-time sequential potentiometric determinations of potassium concentrations from three cochlear regions in noise-exposed rats by MA, Y. L, GERHARDT, K. J, RYBAK, L. P, CURTIS, L. M, RAREY, K. E

“…Double-barrelled potassium selective microelectrodes (K-ISME) were used in situ for real-time sequential determinations of potassium concentrations (CK+) in…”
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Quinine reduces noxious cochlear effects of furosemide and ethacrynic acid by Rybak, L P, Whitworth, C

“…Endocochlear potential (EP) and eighth nerve action potential (AP) were measured in chinchillas. We investigated the interaction of quinine with the loop…”
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4-Methylthiobenzoic Acid Protection against Cisplatin Nephrotoxicity: Antioxidant System by Husain, K., Morris, C., Whitworth, C., Trammel, G.L., Rybak, L.P., Somani, S.M.

“…This study investigates the changes in renal antioxidant system after cisplatin administration and the nephroprotection with 4-methylthiobenzoic acid (MTBA)…”
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