Search Results - "Ryan E, Morgan"

A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development by Morgan, Ryan E, van Staden, Carlo J, Chen, Yuan, Kalyanaraman, Natarajan, Kalanzi, Jackson, Dunn, 2nd, Robert T, Afshari, Cynthia A, Hamadeh, Hisham K

“…The bile salt export pump (BSEP) is expressed at the canalicular domain of hepatocytes, where it serves as the primary route of elimination for monovalent bile…”
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Gastrointestinal complications in pediatric lung transplant recipients: Incidence, risk factors, and effects on patient outcomes by Klouda, Timothy, Ryan E, Morgan, Leonard, Jessica Brie, Freiberger, Dawn, Midyat, Levent, Dahlberg, Suzanne, Rosen, Rachel, Visner, Gary

“…Background Gastrointestinal (GI) complications in lung transplant recipients can occur any time during the post‐operative period, leading to prolonged…”
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Characteristics and use of patient-reported outcomes of clinical trials for high-risk neurological medical devices that received FDA premarket approval from 2001 to 2022 by Ryan, Morgan E, Srivastava, Siddharth, Wan, Lin, Yang, Guang, Zhang, Bo

“…Neurological medical devices have revolutionized the management of neurological disorders, providing diagnostic, therapeutic, and monitoring solutions…”
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A multi-center preclinical study of gadoxetate DCE-MRI in rats as a biomarker of drug induced inhibition of liver transporter function by Karageorgis, Anastassia, Lenhard, Stephen C, Yerby, Brittany, Forsgren, Mikael F, Liachenko, Serguei, Johansson, Edvin, Pilling, Mark A, Peterson, Richard A, Yang, Xi, Williams, Dominic P, Ungersma, Sharon E, Morgan, Ryan E, Brouwer, Kim L R, Jucker, Beat M, Hockings, Paul D

“…Drug-induced liver injury (DILI) is a leading cause of acute liver failure and transplantation. DILI can be the result of impaired hepatobiliary transporters,…”
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Interference with Bile Salt Export Pump Function Is a Susceptibility Factor for Human Liver Injury in Drug Development by Morgan, Ryan E., Trauner, Michael, van Staden, Carlo J., Lee, Paul H., Ramachandran, Bharath, Eschenberg, Michael, Afshari, Cynthia A., Qualls, Charles W., Lightfoot-Dunn, Ruth, Hamadeh, Hisham K.

“…The bile salt export pump (BSEP) is an efflux transporter, driving the elimination of endobiotic and xenobiotic substrates from hepatocytes into the bile. More…”
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Relationship between long-acting reversible contraception and acne in a cohort of adolescents and young adults by Boos, Markus D, Ryan, Morgan E, Milliren, Carly, Golub, Sarah, Maslyanskaya, Sofya, Escovedo, Michelle, DiVasta, Amy, Pitts, Sarah

“…The use of progestin-only long-acting reversible contraception (LARC) may be a risk factor for acne. Few studies have focused primarily on the effects of…”
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Continuation rates of hormonal intrauterine devices in adolescents and young adults when placed for contraceptive and non-contraceptive indications by Shim, Jessica Y, Ryan, Morgan E, Milliren, Carly E, Maslyanskaya, Sofya, Borzutzky, Claudia, Golub, Sarah, Pitts, Sarah, DiVasta, Amy D

“…This study aimed to estimate and compare continuation rates of hormonal intrauterine devices (IUDs) when placed for contraceptive or menstrual management…”
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Long-acting reversible contraception in gender-diverse adolescents and young adults: Outcomes from a multisite collaborative by Abernathey, Liz, Ryan, Morgan E., Golub, Sarah, Ahrens, Kym, Milliren, Carly E., Borzutzky, Claudia, Maslyanskaya, Sofya, DiVasta, Amy D., Pitts, Sarah

“…This study aimed to describe the clinical experience of gender-diverse adolescents and young adults receiving long-acting reversible contraception (LARC). This…”
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Delays to care in infantile epileptic spasms syndrome: Racial and ethnic inequities by Abath, Christina Briscoe, Gupta, Nishtha, Hadjinicolaou, Aristides, Donatelli, Stephanie, Singh, Avantika, Merchant, Sabrina, Ryan, Morgan E., Soby, Meghann, Ryan, Christopher, Nelson, Adrianne Katrina, Maldonado Pacheco, John E., Zhang, Bo, Williams, David N., Yuskaitis, Christopher J., Harini, Chellamani

“…Objective Non‐Hispanic (NH) Black children are less likely to receive a standard treatment course for infantile epileptic spasms syndrome (IESS) than White/NH…”
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Mimics of Pediatric Small Vessel Primary Angiitis of the Central Nervous System by Stredny, Coral M., Blessing, Melissa M., Yi, Vivian, Ryan, Morgan E., Zhang, Bo, Solomon, Isaac H., Prabhu, Sanjay P., Alexandrescu, Sanda, Gorman, Mark P.

“…Objective Small vessel primary angiitis of the central nervous system is a rare and often severe disease characterized by central nervous system‐restricted…”
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An International Pediatric-Onset Opsoclonus-Myoclonus Ataxia Syndrome Registry and Clinical Research Network: Development, Progress, and Vision by Kerr, Lauren M., Ryan, Morgan E., Lim, Ming, Hearn, Sarah, Klein, Andrea, Deiva, Kumaran, Hopkins, Sarah E., Bacchus, Micky K., Sokol, Elizabeth A., Waanders, Angela J., Mitchell, Wendy G., Khakoo, Yasmin, Lotze, Timothy E., Zhang, Bo, Gorman, Mark P.

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Intravital Multiphoton Microscopy with Fluorescent Bile Salts in Rats as an In Vivo Biomarker for Hepatobiliary Transport Inhibition by Ryan, Jennifer, Morgan, Ryan E, Chen, Yuan, Volak, Laurie P, Dunn, 2nd, Robert T, Dunn, Kenneth W

“…The bile salt export pump (BSEP) is expressed at the canalicular domain of hepatocytes, where it mediates the elimination of monovalent bile salts into the…”
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A clinical flow cytometric biomarker strategy: validation of peripheral leukocyte phospholipidosis using Nile red by Halstead, Bartley W., Zwickl, Craig M., Morgan, Ryan E., Monteith, David K., Thomas, Craig E., Bowers, Rita K., Berridge, Brian R.

“…Phospholipidosis, or intracellular accumulation of phospholipids, is caused by specific classes of xenobiotics. This phenomenon represents a challenge for risk…”
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In vitro assays and biomarkers for drug-induced phospholipidosis by Monteith, David K, Morgan, Ryan E, Halstead, Bartley

“…Drug-induced phospholipidosis is the cytoplasmic accumulation of phospholipids as a result of xenobiotic exposure. This accumulation results in a unique…”
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30. Intrauterine Device Experiences in Gender Diverse Adolescents and Young Adults: A Multisite Study by Abernathey, Liz, Ryan, Morgan E., Pitts, Sarah, DiVasta, Amy, Ahrens, Kym, Maslyanskaya, Sofya, Milliren, Carly, Escovedo, Michelle, Golub, Sarah

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125. Long-acting Reversible Contraception in Gender Diverse Adolescents and Young Adults: Outcomes from a Multi-site Collaborative by Abernathey, Liz, Golub, Sarah, Ahrens, Kym, Ryan, Morgan E., Milliren, Carly, Maslyanskaya, Sofya, Borzutzky, Claudia, DiVasta, Amy, Pitts, Sarah

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4. Continuation Rates of Intrauterine Devices in Adolescents and Young Adults when placed for Contraceptive and Non-Contraceptive Indications by Shim, Jessica Y., Ryan, Morgan E., Milliren, Carly E., Pitts, Sarah, DiVasta, Amy D., Maslyanskaya, Sofya, Borzutzky, Claudia, Golub, Sarah

“…The intrauterine device (IUD) is a long-acting reversible contraceptive with potential non-contraceptive benefits. Adolescents and young adults (AYA) may seek…”
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83. Long-acting Reversible Contraception in Gender Diverse Adolescents and Young Adults: Outcomes from a Multi-site Collaborative by Abernathey, Liz, Golub, Sarah, Ahrens, Kym, Ryan, Morgan E., Milliren, Carly E., DiVasta, Amy D., Pitts, Sarah, Maslyanskaya, Sofya, Borzutzky, Claudia

“…To our knowledge, no studies have specifically sought to understand the use of long-acting reversible contraception (LARC) by gender diverse adolescents and…”
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Susceptibility of pine plantations to attack by the pine shoot beetle (Tomicus piniperda L.) in southern Ontario by Morgan, Ryan E

“…Tomicus piniperda (L.) (Coleoptera: Scolytidae), was discovered in Ohio in 1992 and spread throughout southern Ontario, Quebec, and the United States. The…”
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Susceptibility of pine plantations to attack by the pine shoot beetle (Tomicus piniperda L.) in southern Ontario by Morgan, Ryan E

“…Tomicus piniperda (L.) (Coleoptera: Scolytidae), was discovered in Ohio in 1992 and spread throughout southern Ontario, Quebec, and the United States. The…”
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