Search Results - "Ryan, W J"
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A Model To Estimate Carbon Dioxide Injectivity and Storage Capacity for Geological Sequestration in Shale Gas Wells
Published in Environmental science & technology (04-08-2015)“…Recent studies suggest the possibility of CO2 sequestration in depleted shale gas formations, motivated by large storage capacity estimates in these…”
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Tryptophan C-mannosylation is critical for Plasmodium falciparum transmission
Published in Nature communications (29-07-2022)“…Tryptophan C-mannosylation stabilizes proteins bearing a thrombospondin repeat (TSR) domain in metazoans. Here we show that Plasmodium falciparum expresses a…”
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Numerical Modeling of Gas and Water Flow in Shale Gas Formations with a Focus on the Fate of Hydraulic Fracturing Fluid
Published in Environmental science & technology (05-12-2017)“…Hydraulic fracturing in shale gas formations involves the injection of large volumes of aqueous fluid deep underground. Only a small proportion of the injected…”
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Correction to A Model To Estimate Carbon Dioxide Injectivity and Storage Capacity for Geological Sequestration in Shale Gas Wells
Published in Environmental science & technology (18-08-2020)Get full text
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Publisher Correction: Tryptophan C-mannosylation is critical for Plasmodium falciparum transmission
Published in Nature communications (23-08-2022)Get full text
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The myelin water imaging transcriptome: myelin water fraction regionally varies with oligodendrocyte-specific gene expression
Published in Molecular brain (23-07-2024)“…Identifying sensitive and specific measures that can quantify myelin are instrumental in characterizing microstructural changes in neurological conditions…”
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Platelet derived growth factor receptor β (PDGFRβ) is a host receptor for the human malaria parasite adhesin TRAP
Published in Scientific reports (31-05-2021)“…Following their inoculation by the bite of an infected Anopheles mosquito, the malaria parasite sporozoite forms travel from the bite site in the skin into the…”
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Plasmodium falciparum Liver Stage Infection and Transition to Stable Blood Stage Infection in Liver-Humanized and Blood-Humanized FRGN KO Mice Enables Testing of Blood Stage Inhibitory Antibodies (Reticulocyte-Binding Protein Homolog 5) In Vivo
Published in Frontiers in immunology (14-03-2018)“…The invention of liver-humanized mouse models has made it possible to directly study the preerythrocytic stages of . In contrast, the current models to…”
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Epitope-coated polymer particles elicit neutralising antibodies against Plasmodium falciparum sporozoites
Published in npj vaccines (29-11-2021)“…The current Malaria RTS,S vaccine is based on virus-like particles (VLPs) comprising the NANP repetitive epitopes from the cicumsporozoite protein (CSP) of…”
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Delta-9-tetrahydrocannabinol disrupts hippocampal neuroplasticity and neurogenesis in trained, but not untrained adolescent Sprague-Dawley rats
Published in Brain research (22-02-2014)“…Abstract Cannabis is the most widely used illicit drug, and disruption of learning and memory are commonly reported consequences of cannabis use. We have…”
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Infrastructure to enable deployment of carbon capture, utilization, and storage in the United States
Published in Proceedings of the National Academy of Sciences - PNAS (18-09-2018)“…In February 2018, the United States enacted significant financial incentives for carbon capture, utilization, and storage (CCUS) that will make capture from…”
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Plasmodium yoelii S4/CelTOS is important for sporozoite gliding motility and cell traversal
Published in Cellular microbiology (01-04-2018)“…Gliding motility and cell traversal by the Plasmodium ookinete and sporozoite invasive stages allow penetration of cellular barriers to establish infection of…”
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An Opsonic Phagocytosis Assay for Plasmodium falciparum Sporozoites
Published in Clinical and vaccine immunology (01-02-2017)“…Plasmodium falciparum malaria remains the deadliest parasitic disease worldwide. Vaccines targeting the preerythrocytic sporozoite and liver stages have the…”
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Shale Gas Well, Hydraulic Fracturing, and Formation Data to Support Modeling of Gas and Water Flow in Shale Formations
Published in Water resources research (01-04-2018)“…The potential for shale gas development and hydraulic fracturing to cause subsurface water contamination has prompted a number of modeling studies to assess…”
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Strategic Carbon Dioxide Infrastructure to Achieve a Low-Carbon Power Sector in the Midwestern and South-Central United States
Published in Environmental science & technology (16-11-2021)“…Large-scale carbon capture, utilization, and storage (CCUS) requires development of critical infrastructure to connect capture locations to geological storage…”
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Flp/ FRT -mediated disruption of ptex150 and exp2 in Plasmodium falciparum sporozoites inhibits liver-stage development
Published in Proceedings of the National Academy of Sciences - PNAS (09-07-2024)“…causes severe malaria and assembles a protein translocon (PTEX) complex at the parasitophorous vacuole membrane (PVM) of infected erythrocytes, through which…”
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Immunization of Malaria-Preexposed Volunteers With PfSPZ Vaccine Elicits Long-Lived IgM Invasion-Inhibitory and Complement-Fixing Antibodies
Published in The Journal of infectious diseases (23-04-2018)“…We show that functional antisporozoite IgM antibodies are induced in Tanzanian volunteers immunized with radiation attenuated, aseptic, purified, cryopreserved…”
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Complete attenuation of genetically engineered Plasmodium falciparum sporozoites in human subjects
Published in Science translational medicine (04-01-2017)“…Immunization of humans with whole sporozoites confers complete, sterilizing immunity against malaria infection. However, achieving consistent safety while…”
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An expanding toolkit for preclinical pre-erythrocytic malaria vaccine development: bridging traditional mouse malaria models and human trials
Published in Future microbiology (01-12-2016)“…Malaria remains a significant public health burden with 214 million new infections and over 400,000 deaths in 2015. Elucidating relevant parasite biology can…”
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Targeting the Extrinsic Pathway of Hepatocyte Apoptosis Promotes Clearance of Plasmodium Liver Infection
Published in Cell reports (Cambridge) (31-03-2020)“…Plasmodium sporozoites infect the liver and develop into exoerythrocytic merozoites that initiate blood-stage disease. The hepatocyte molecular pathways that…”
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