Search Results - "Ryan, Timothy M"

Gracility of the modern Homo sapiens skeleton is the result of decreased biomechanical loading by Ryan, Timothy M., Shaw, Colin N.

“…The postcranial skeleton of modern Homo sapiens is relatively gracile compared with other hominoids and earlier hominins. This gracility predisposes…”
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Anatomical basis and physiological role of cerebrospinal fluid transport through the murine cribriform plate by Norwood, Jordan N, Zhang, Qingguang, Card, David, Craine, Amanda, Ryan, Timothy M, Drew, Patrick J

“…Cerebrospinal fluid (CSF) flows through the brain, transporting chemical signals and removing waste. CSF production in the brain is balanced by a constant…”
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Improved radiation dose efficiency in solution SAXS using a sheath flow sample environment by Kirby, Nigel, Cowieson, Nathan, Hawley, Adrian M., Mudie, Stephen T., McGillivray, Duncan J., Kusel, Michael, Samardzic-Boban, Vesna, Ryan, Timothy M.

“…Radiation damage is a major limitation to synchrotron small‐angle X‐ray scattering analysis of biomacromolecules. Flowing the sample during exposure helps to…”
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Exploring sexual dimorphism of the modern human talus through geometric morphometric methods by Sorrentino, Rita, Belcastro, Maria Giovanna, Figus, Carla, Stephens, Nicholas B, Turley, Kevin, Harcourt-Smith, William, Ryan, Timothy M, Benazzi, Stefano

“…Sex determination is a pivotal step in forensic and bioarchaeological fields. Generally, scholars focus on metric or qualitative morphological features, but in…”
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Gourds and squashes (Cucurbitaspp.) adapted to megafaunal extinction and ecological anachronism through domestication by Kistler, Logan, Newsom, Lee A., Ryan, Timothy M., Clarke, Andrew C., Smith, Bruce D., Perry, George H.

“…The genusCucurbita(squashes, pumpkins, gourds) contains numerous domesticated lineages with ancient New World origins. It was broadly distributed in the past…”
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New species from Ethiopia further expands Middle Pliocene hominin diversity by Haile-Selassie, Yohannes, Gibert, Luis, Melillo, Stephanie M., Ryan, Timothy M., Alene, Mulugeta, Deino, Alan, Levin, Naomi E., Scott, Gary, Saylor, Beverly Z.

“…Middle Pliocene hominin species diversity has been a subject of debate over the past two decades, particularly after the naming of Australopithecus…”
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Does skeletal anatomy reflect adaptation to locomotor patterns? cortical and trabecular architecture in human and nonhuman anthropoids by Shaw, Colin N., Ryan, Timothy M.

“…Although the correspondence between habitual activity and diaphyseal cortical bone morphology has been demonstrated for the fore‐ and hind‐limb long bones of…”
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Unique suites of trabecular bone features characterize locomotor behavior in human and non-human anthropoid primates by Ryan, Timothy M, Shaw, Colin N

“…Understanding the mechanically-mediated response of trabecular bone to locomotion-specific loading patterns would be of great benefit to comparative mammalian…”
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South-to-north migration preceded the advent of intensive farming in the Maya region by Kennett, Douglas J., Lipson, Mark, Prufer, Keith M., Mora-Marín, David, George, Richard J., Rohland, Nadin, Robinson, Mark, Trask, Willa R., Edgar, Heather H. J., Hill, Ethan C., Ray, Erin E., Lynch, Paige, Moes, Emily, O’Donnell, Lexi, Harper, Thomas K., Kate, Emily J., Ramos, Josue, Morris, John, Gutierrez, Said M., Ryan, Timothy M., Culleton, Brendan J., Awe, Jaime J., Reich, David

“…The genetic prehistory of human populations in Central America is largely unexplored leaving an important gap in our knowledge of the global expansion of…”
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Trabecular Bone Structure in the Humeral and Femoral Heads of Anthropoid Primates by Ryan, Timothy M., Walker, Alan

“…The functional significance of three‐dimensional trabecular bone architecture in the primate postcranial skeleton has received significant interest over the…”
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Protic Ionic Liquid Cation Alkyl Chain Length Effect on Lysozyme Structure by Han, Qi, Broomhall, Hayden C, Vieira Veríssimo, Nathalia, Ryan, Timothy M, Drummond, Calum J, Pereira, Jorge F B, Greaves, Tamar L

“…Solvents that stabilize protein structures can improve and expand their biochemical applications, particularly with the growing interest in biocatalytic-based…”
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The influence of mobility strategy on the modern human talus by Sorrentino, Rita, Stephens, Nicholas B., Carlson, Kristian J., Figus, Carla, Fiorenza, Luca, Frost, Stephen, Harcourt‐Smith, William, Parr, William, Saers, Jaap, Turley, Kevin, Wroe, Stephen, Belcastro, Maria G., Ryan, Timothy M., Benazzi, Stefano

“…Objectives The primate talus is known to have a shape that varies according to differences in locomotion and substrate use. While the modern human talus is…”
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Morphometric analysis of the hominin talus: Evolutionary and functional implications by Sorrentino, Rita, Carlson, Kristian J., Bortolini, Eugenio, Minghetti, Caterina, Feletti, Francesco, Fiorenza, Luca, Frost, Stephen, Jashashvili, Tea, Parr, William, Shaw, Colin, Su, Anne, Turley, Kevin, Wroe, Stephen, Ryan, Timothy M., Belcastro, M. Giovanna, Benazzi, Stefano

“…The adoption of bipedalism is a key benchmark in human evolution that has impacted talar morphology. Here, we investigate talar morphological variability in…”
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Growth and development of trabecular structure in the calcaneus of Japanese macaques (Macaca fuscata) reflects locomotor behavior, life history, and neuromuscular development by Saers, Jaap P. P., Gordon, Adam D., Ryan, Timothy M., Stock, Jay T.

“…Bone structure dynamically adapts to its mechanical environment throughout ontogeny by altering the structure of trabecular bone, the three‐dimensional…”
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Using point clouds to investigate the relationship between trabecular bone phenotype and behavior: An example utilizing the human calcaneus by DeMars, Lily J. D., Stephens, Nicholas B., Saers, Jaap P. P., Gordon, Adam, Stock, Jay T., Ryan, Timothy M.

“…Objectives The objective of this study is to demonstrate a new method for analyzing trabecular bone volume fraction and degree of anisotropy in three…”
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The Primate Semicircular Canal System and Locomotion by Spoor, Fred, Garland, Theodore, Krovitz, Gail, Ryan, Timothy M., Silcox, Mary T., Walker, Alan

“…The semicircular canal system of vertebrates helps coordinate body movements, including stabilization of gaze during locomotion. Quantitative phylogenetically…”
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Trabecular Bone Structure in the Distal Femur of Humans, Apes, and Baboons by Sukhdeo, Simone, Parsons, Jacob, Niu, Xiaoyue Maggie, Ryan, Timothy M.

“…ABSTRACT Trabecular bone structure has been used to investigate the relationship between skeletal form and locomotor behavior on the premise that trabecular…”
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Complex variation of trabecular bone structure in the proximal humerus and femur of five modern human populations by Doershuk, Lily J., Saers, Jaap P. P., Shaw, Colin N., Jashashvili, Tea, Carlson, Kristian J., Stock, Jay T., Ryan, Timothy M.

“…Objective This project investigates trabecular bone structural variation in the proximal humerus and femur of hunter‐gatherer, mixed‐strategy agricultural,…”
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Combinations of trabecular and cortical bone properties distinguish various loading modalities between athletes and controls by Saers, Jaap P. P., DeMars, Lily J., Stephens, Nicholas B., Jashashvili, Tea, Carlson, Kristian J., Gordon, Adam D., Shaw, Colin N., Ryan, Timothy M., Stock, Jay T.

“…Objectives Variation in trabecular and cortical bone properties is often used to infer habitual behavior in the past. However, the structures of both types of…”
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Utility of an improved model of amyloid-beta (Aβ₁₋₄₂) toxicity in Caenorhabditis elegans for drug screening for Alzheimer's disease by McColl, Gawain, Roberts, Blaine R, Pukala, Tara L, Kenche, Vijaya B, Roberts, Christine M, Link, Christopher D, Ryan, Timothy M, Masters, Colin L, Barnham, Kevin J, Bush, Ashley I, Cherny, Robert A

“…The definitive indicator of Alzheimer's disease (AD) pathology is the profuse accumulation of amyloid-ß (Aß) within the brain. Various in vitro and cell-based…”
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